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Field Trial Determining the Strain Survival Variability of Salmonella Spp e Coli 0157 STEC Non-0157 and Generic E Coli in Manure Amended Agricultural Soils

Department of Health and Human Services, Food and Drug Administration | Published March 14, 2016  -  Deadline March 29, 2016
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Synopsis - Notice of Intent to Sole Source This synopsis is hereby issued in accordance with FAR Part 5.203 in response to the mandatory requirement for a 15 day notification. The purpose of this synopsis is to announce the Food and Drug Administration's intent to negotiate a Firm Fixed Price sole source contract with Virginia Tech Eastern Shore Agricultural Research and Extension Center (ESAREC), located at 33446 Research Drive, Painter, VA 23420 for the purpose investigating the impact of pathogen strain on the survival of Salmonella spp., Escherichia coli (E.coli) 0157, Shiga toxin-producing E. coli (STEC) non-0157, and generic Escherichia coli in manure amended soils under greenhouse conditions. The Government intends to negotiate solely with VIRGINIA TECH EASTERN SHORE AGRICULUTRAL RESEARCH AND EXTENSION CENTER per FAR 6.302-1, as no other source of supplies will satisfy agency requirements. -Previous field trails performed by ESAREC involved testing for Sen in water, amended soil, and poultry facilities. Continuity of methods and accessibility to facilities is required for the current sampling and testing results to be validly coupled and statistically analyzed. -The outbreak strain of SeN has been isolated from the Virginia Tech Eastern Shore Agricultural Research and Extension Center (ESAREC) environment by the FDA over the past three seasons, particularly in the farm ponds.-There is no other location in the USA where Salmonella enterica Newport (SeN) has been found and confirmed to be endemic in the environment of tomato growth. Doing this field trail in another location would necessitate introducing SeN into the environment. ESAREC will provide the Government with the following services at an anticipated total cost of $ 181,209.00:Conduct greenhouse experiments to collect data on the survival dynamics of; -15 strains of Salmonella, inoculated into raw poultry manure, amended into two types of soil, and subjected to simulated rain. -4 strains of generic E. Coli, 10 strains of E. coli 0157, and 4 strains of STEC non-0157, inoculated into raw cattle manure, amended into two types of soil, and subjected to rain. -Provide raw data and statistical analysis to characterize how survival dynamics varies among the strains evaluated. THIS NOTICE IS NOT A REQUEST FOR COMPETITIVE PROPOSALS, however, interested firms may submit a capability statement in response to the above requirement with pricing information by March 29th, 2016 @ 4:30 PM Local Time to Christopher McGucken, Contract Specialist, Phone: (240) 402-7599, Email: Christopher.McGucken@fda.hhs.gov. A determination not to open competition based responses to this notice is solely within the discretion of the Government.

eSync Training Monitoring Application

Department of Health and Human Services, Health Resources and Services Administration | Published September 11, 2016  -  Deadline September 21, 2016
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eSync Training Monitoring Application subscription for hosting, configuration, and support of the application under CoSo FedRAMP environment. eSync application will allow all end-users to leverage video integration seamlessly. The eSync’s application gives the Super Review Administrator (RA) full control of 15 simultaneous meetings ensuring the quality assurance of each meeting.

Sample Collection and Microbial Analysis of FDA Priority Tree Fruit Commodities and Their Production Environments

Department of Health and Human Services, Food and Drug Administration | Published August 4, 2016  -  Deadline August 19, 2016
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FDA-NOI –1164936 Synopsis – Notice of Intent to Sole Source   This synopsis is hereby issued in accordance with FAR Part 5.203 in response to the mandatory requirement for a 15 day notification. The purpose of this synopsis is to announce that the Food and Drug Administration’s intents to negotiate a Firm Fixed Price sole source contract with Pennsylvania State Fruit Research and Extension Center located at 290 University Dr., P.O. Box 330 Biglerville, PA 17307-0330.   The Government intends to negotiate solely with Pennsylvania State University per FAR 6.302-1, as no other source of supplies will satisfy agency requirements.   The FDA’s intent is to obtain a multiple year award (a minimum of 3 years) for environmental surveillance data on the incidence and prevalence of L. monocytogenes in stone and apple fruit production environments. Because the huge variation of weather from year to year, a single year of data would not be representative or reliable enough to be the basis of any public health policy decisions.   Pennsylvania State University has a long history of research, facilities and resources which includes a large scale orchard, including many different fruits, which is very unique for research. There are also nearby large fruit orchards that are representative of regular fruit production within the United States. Multiyear sampling of representative commercial orchards, fruit packing, and storage facilities is critical to determine if L. monocytogenes distribution within the orchards can be tied to commercial packinghouses and downstream food distribution systems.   THIS NOTICE IS NOT A REQUEST FOR COMPETITIVE PROPOSALS, however, interested firms may submit a capability statement in response to the above requirement with reference to FDA-NOI-1164936 and pricing information by August 19th, 2016 @ 2:30 PM EST to Naomi Carter, Contract Specialist, Email: Naomi.Carter@fda.hhs.gov. A determination not to open competition based responses to this notice is solely within the discretion of the GovernmentFDA-NOI -1164936Synopsis - Notice of Intent to Sole Source This synopsis is hereby issued in accordance with FAR Part 5.203 in response to the mandatory requirement for a 15 day notification. The purpose of this synopsis is to announce that the Food and Drug Administration's intents to negotiate a Firm Fixed Price sole source contract with Pennsylvania State Fruit Research and Extension Center located at 290 University Dr., P.O. Box 330 Biglerville, PA 17307-0330. The Government intends to negotiate solely with Pennsylvania State University per FAR 6.302-1, as no other source of supplies will satisfy agency requirements. The FDA's intent is to obtain a multiple year award (a minimum of 3 years) for environmental surveillance data on the incidence and prevalence of L. monocytogenes in stone and apple fruit production environments. Because the huge variation of weather from year to year, a single year of data would not be representative or reliable enough to be the basis of any public health policy decisions. Pennsylvania State University has a long history of research, facilities and resources which includes a large scale orchard, including many different fruits, which is very unique for research. There are also nearby large fruit orchards that are representative of regular fruit production within the United States. Multiyear sampling of representative commercial orchards, fruit packing, and storage facilities is critical to determine if L. monocytogenes distribution within the orchards can be tied to commercial packinghouses and downstream food distribution systems. THIS NOTICE IS NOT A REQUEST FOR COMPETITIVE PROPOSALS, however, interested firms may submit a capability statement in response to the above requirement with reference to FDA-NOI-1164936 and pricing information by August 19th, 2016 @ 2:30 PM EST to Naomi Carter, Contract Specialist, Email: Naomi.Carter@fda.hhs.gov. A determination not to open competition based responses to this notice is solely within the discretion of the Government.  

Pragmatic Data HL7 Data Exchange and Elist software license and maintenance; and professional services

Department of Health and Human Services, Food and Drug Administration | Published July 15, 2016  -  Deadline August 1, 2016
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The U.S. Food and Drug Administration intends to negotiate and award on a sole source basis to Pragmatic Data, Inc, under the authority 41 U.S.C. 253(c) (1), as set forth in FAR 6.302-1. This acquisition is in support of the FDA's HL7 data exchange services and automated drug registration and listing system (eLIST). HL7 data exchange service is essential for the processing of HL7 data files. HL7 data exchange services require a perpetual license for the Pragmatic Data Integrator, Adverse Event Modules, Review and Edit, and PRPPLR modules in order to continue using the HL7 date exchange services to meet various requirements. FDA also requires an annual license for the Pragmatic Data Edit and Review module for processing many types of SPL files and various other HL7 standardized data. In addition, FDA is renewing the license for the Pragmatic Data HL7 exchange standard testing and evaluation environment software to allow continued testing HL7 data exchange standards. The eLIST system supports the FDA's regulation for industry to submit timely product content of labeling, facility, registration and listing information in an electronic format. FDA has procured Regulatory Business Data Management Database (RBDMD) and integrated services (including PRPLLR) software licenses. Annual maintenance for these licenses is required to continue eList regulatory operations. The purpose of this requirement is to obtain perpetual licenses for pragmatic data integrator, adverse event modules, review and edit, and PRPLLR modules; continued annual software license and maintenance for the pragmatic review and edit module with Xforms and adverse events; annual license for the pragmatic testing environment and professional services support for the implementation and use of the eLIST system. Pragmatic Data is the only source for the software and there are no authorized resellers or 3rd parties that can provide pragmatic licenses and maintenance; and professional services. The NAICS code is 541512 and the size standard is $27.5M. This notice is not a request for competitive quotations. However, any firm that believes it can meet these requirements may submit a written response via email to Danielle Pena at the email address below by 10:00 AM Eastern Time on August 1, 2016. Supporting evidence must be furnished in sufficient detail to demonstrate the ability to comply with the above requirement. Information received will be considered; however, a determination by the Government not to compete the proposed acquisition based on responses to this notice is solely within the discretion of the Government. If no responses are received, the FDA will proceed with the sole source award to Pragmatic Data, 8839 Rexford Rd, Indianapolis, IN 46260. No phones calls will be accepted. If you have any questions regarding this announcement, please contact Danielle Peña at danielle.pena@fda.hhs.gov.

Small Rural Hospital Transition Project

Department of Health and Human Services, Health Resources and Services Administration | Published May 17, 2016  -  Deadline June 23, 2016
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The Health Resources and Services Administration (HRSA) is issuing the Request for Quotation (RFQ) under the referenced number. Your organization is invited to submit a quote in accordance with the requirements set forth in the attached solicitation. The period of performance is for a base year of 12 months with four (4), 12 month option years, if exercised. This is 100% Small Business Set-Aside. A Firm-Fixed Price type purchase order shall be issued. The NAICS Code for this procurement is 541990 and the PSC Code is R425. Questions or issues for which you require clarification or correction by the Government must be furnished electronically via email to Ms. LaTarsha Rogers at lrogers@hrsa.gov. In order to allow a reply to be provided to all prospective Offerors before submission of their price quote, your questions must be received no later than 9:00 AM Eastern Standard Time (EST) on Tuesday, June 7, 2016. Questions received after the due date and time shall not be considered. NO EXCEPTIONS. Your proposal must be signed by an official authorized to bind your organization and submitted to LaTarsha Rogers by email in PDF format at lrogers@hrsa.gov, no later than Thursday, June 23, 2016 at 9:00 am Eastern Standard Time (EST). You must also request a delivery receipt to ensure timely receipt of proposals. The purpose of this procurement is to provide on-site technical assistance to nine (9) small rural hospitals. The technical assistance services shall prepare nine (9) small rural hospitals for transitioning to the new health care environment. Eligible hospitals must be located in a rural (non-metro) persistent poverty county or a rural census tract of a metro persistent poverty county as defined by FORHP and have 49 staffed beds or less as reported on the hospital's most recently filed Medicare Cost Report.

Intent to Sole Source: Migtation of Current GovNet-NG Application and Database

Department of Health and Human Services, Program Support Center | Published April 1, 2015  -  Deadline April 3, 2015
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Pursuant to the authority of FAR 13.106-1(b)(1)(i), the Contracting Officer may solicit from one source if the Contracting Officer determines that the circumstances of the contract action deem only one source is reasonably available. The Department of Health and Human Services (DHHS), Program Support Center (PSC), Financial Management Services (FMS), intends to sole source to: Starry Associates, Inc. 175 Admiral Cochrane Drive Suite 100 Annapolis, MD 21401-7316 PSC/FMS requires migration of their current GovNet-NG application and database from the existing servers with Windows 2003 operating system to the new servers with Windows 2012-R2 operating systems in response to the Department of Health and Human Services (DHHS) Information Technology (IT) mandate to have all servers upgraded to Windows 2012 by July, 14, 2015. Migration of the GovNet-NG application will involve reinstalling all components of the application. Oracle database and Glassfish servers will be installed on the new virtual server environment. Starry Associates' web-enabled system addresses the need for a data and report repository offering a complete, accurate, and customized inquiries and reports. GovNet-NG was developed and customized to meet PSC/FMS requirements for full data repository, data warehouse, and report repository. GovNet-NG contains substantial security measures to ensure that each user gains access to only that portion of the data they are given authorization to view. In addition, GovNet-NG's ability to access data online has significantly reduced the cost of printing out specific reports and having those reports mailed. This is not a solicitation for competitive proposal. No solicitation document is available. All responsible sources that have determined that they can provide the same services may submit product information and a capabilities statement addressing their specific abilities regarding this requirement. The email subject line must reference PSC150337. All responses are due by April 3, 2015, 2:00 PM Eastern Time and can be sent to Zipora Chepkoit at Zipora.Chepkoit@psc.hhs.gov. A determination by the Government not to compete this proposed contract base upon responses to this notice is solely within the discretion of the Government.

Cartagenia BENCH Lab NGS/Bench Connector

Department of Health and Human Services, National Institutes of Health | Published December 11, 2014  -  Deadline December 19, 2014
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THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (BRAND-NAME-Cartagenia Inc.). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR A PROPOSAL. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. INTRODUCTION: The National Institute of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI) Office of Acquisition (OA) on behalf of the National Human Genome Research Institute, (NHGRI), intends to negotiate and award a purchase order on a noncompetitive sole source basis to Cartagenia, 485 Massachusetts Avenue, Suite 300, Cambridge, MA 02139-0418 to provide THIS IS A FOLLOW-ON REQUIREMENT IT SECURITY PROVISIONS AND 508 COMPLIANCE LANGUAGE IS ALREADY OBTAINED FROM PREVIOUS CONTRACT. Procurement: 1. Add Amazon Web Services; 2. Set-up new dedicated private cloud, VPN and firewall and adapt Bench Connector to new environment;and 3. Support Assistance for Bench NGS and Bench Connector optimization in the UDPics environment (for 60-Days). BACKGROUND: The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency conducting and supporting medical discoveries that improve people's health and save lives. The National Human Genome Research Institute (NHGRI), National Institutes of Health Undiagnosed Disease Program (UDP) is a pilot program designed to address the needs of persons with debilitating medical conditions for which no diagnosis has been found despite an extensive workup. The goals of the UDP include finding accurate diagnoses and discovering new diseases that provide insight into human physiology and genetics. The multi- user nature of NIH's UDP Translational Laboratory, along with its dynamic process structures, engenders a deep set of requirements for any candidate data and project management system. UDP continues to work in conjunction with Cartagenia to continue providing Bench NGS and Bench Connector services and support to NHGRI UDP LIMS System. Cartagenia is the sole provider of the BENCH platform of software that the UDP laboratory has used for the past year. This software platform is unique that it offers a standardized data interpretation from both high-throughput Next Generation Sequencing and microarray data for its analysis and has been modified to fit NHGRI needs. The BENCH platform has the ability to detect structural and molecular variation measured by different technologies that includes copy number variation, loss of heterozygosity, single nucleotide polymorphisms, insertions and deletions, and variant classification status (benign, pathogenic, etc.) Objectives: Cartagenia Bench platform software is required by the Undiagnosed Diseases laboratory to reliably and systematically sift through large lists of patient genome variants derived from next generation sequencing and SNP microarray data in order to make informed calls on variants that are potentially deleterious and the cause of the unique disorders seen in admitted Undiagnosed Diseases Program patients. The intramural NIH Undiagnosed Diseases Program (UDP) has been given the additional mandates of founding and training extramural UDP sites and providing classes for analysis of next generation sequencing data and SNP chips. To this end, the UDP requires a mechanism by which it can uniformly provide mentoring and a common database for analysis of genomic and sequence variants. Period of Performance: Twelve (12) months from the date of award. JUSTIFICATION: The Cartagenia BENCH Communication Module (BCM) has already been integrated into the UDP LIMs system. In conjunction with NIH Security Standards, Cartagenia shall supply the hosting of Amazon Web Services. Additionally, they shall develop and set up the newly dedicated UDP private cloud, VPN and firewall in order to meet the specifics of the UDP LIMs system. Finally, Cartagenia shall provide the optimization of both BENCH NGS and BENCH Connector to this new environment. These integration services are an integral part of the LIMS development and connectivity that will allow the transfer of data from the Cartagenia software to other analysis software, to collaborators and to generate necessary reports. Cartagenia is the sole provider of the BENCH platform software and is the only provider of the BENCH Communication Module as well as the LIMs Integration services that will accompany the module. REGULATORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13.106-1(b) Soliciting from a single source, only one responsible source and no other supplies or services will satisfy agency requirements. ADDITIONAL INFORMATION Industry Classification (NAICS) Code is 541511, Custom Programming Services, small business size standard is $25.5M. The acquisition is being conducted under FAR Part 13, simplified acquisition procedures, therefore the requirements of FAR Part 6 B Competitive Requirements are not applicable (FAR Part 6.001). The resultant Contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 05-78 (November 25, 2014). This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by December 19, 2014 and must reference synopsis number HHS-NIH-NHLBI-CSB-(HG)-2015-042-DLM, may be submitted to the National, Heart, Lung and Blood Institute, Office of Acquisition, COAC Services Branch, 6701 Rockledge Drive, Suite 6149, Bethesda, Maryland 20892-7902, Attention: Dorothy Maxwell. Response may be submitted electronically to maxwelld@mail.nih.gov. Faxes will not be accepted. Responses will only be accepted if dated and signed by an authorized company representative. "All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency."

FDA CDER Portes O&M SAS Drug Development Software Maintenance

Department of Health and Human Services, Food and Drug Administration | Published April 13, 2016  -  Deadline April 27, 2016
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The U.S. Food and Drug Administration intends to award a contract for operations and maintenance support of the Portes system to Executive Information Systems (EIS), 6901 Rockledge Drive, Suite 600, Bethesda, MD 20827. Portes uses COTS software to create an environment where authorized users and software tools can access application studies after they have been processed by the SAS Drug Development (SDD) software. The software tools interface with Portes via an Application Programming Interface built into the SDD COTS product. The Portes system is implemented within the FDA's Information System Architecture (ISA) as evidenced by the Authority to Operate (ATO) designation that was granted by the FDA in 2014. In order to fully support Portes operational and maintenance needs, the FDA requires application support in the test/pre-production/production environments; upgrade existing SDD from the current version of 3.5 to the most up to date version 4.x to comply with FDA IT standards for server infrastructure; and, SDD software maintenance. EIS's GSA Federal Supply Schedule includes the required professional services to support the application support and upgrade; however, EIS's FSS does not include the SDD software maintenance. EIS is the only SAS authorized GSA FSS reseller to the US Government of SAS professional services performed by SAS personnel based on an exclusive arrangement for resale on Government schedule contracts. For administrative convenience, the FDA intends to add the SDD software maintenance to the resultant EIS Federal Supply Schedule order in accordance with the procedures set forth in 8.402(f). The Government intends to solicit and negotiate with only one source under the authority of FAR 6.302-1. Interested entities may identify their interest and capability to respond to the requirement or submit quotation no later than 5pm Eastern Time on Wednesday, April 27th. This notice is not a request for quotation. Any vendor that believes it can provide the above stated requirements can provide supporting documents demonstrating their capability and specifications statement. The FDA will review all responses received; however, the Government retains the sole discretion not to further compete the proposed acquisition based on responses to this notice. Information can be sent to Danielle Pena at Danielle.Pena@fda.hhs.gov. No telephone requests will be accepted.

RSA Software and Tokens

Department of Health and Human Services, Program Support Center | Published July 8, 2015  -  Deadline July 13, 2015
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(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is OS154232. (iii) This solicitation and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-82 (iv) The corresponding NAICS code is 423430 (v) List of contract line item number(s) and items, quantities and units of measure PART # DESCRIPTION (Reference License # 99768790) QTY Unit Price Total Price AUT0000250EE1 1MO MNT AUTH MGR ENT PER U F/QTY 155-250 1920 AUT0000250Y2EE1 1MO EXTD MNT AM 6/7 ENT ENH 1920 SID820-8-60-36-A 36MO SECURID SW TOKEN SEEDS PER USER FOR QTYS BETWEEN 10-250 10 SID700-6-60-36-50 50PK RSA SID 700 3YR TOKEN AUTHENTICATOR 3 PS-BAS-SID-GCURR GETCURRENT SID SVR AND APPL 1 Total Price (vi) Description of Requirement - The US Department of Health and Human Services (DHHS), Office of the Secretary (OS), Assistant Secretary for Administration (ASA), Office of the Chief Information Officer (OCIO), requires the renewal of its annual maintenance subscription for RSA software and tokens. RSA Tokens are used for two-factor authentication in the OS network environment for systems that cannot use PIV card authentication. (vii) Delivery and these services are to be for 12 months from award date. (viii) The provision at FAR 52.212-1, Instructions to Offerors - Commercial Items (APR 2014), applies to this acquisition. (ix) The provision at FAR 52.212-2, Evaluation - Commercial Items (OCT 2014), applies to this acquisition. The Government will award a contract resulting from this synopsis/solicitation to the responsible offeror who provides the lowest price and is technically acceptable (LPTA). (x) Offerors are to include a completed copy of the provision at FAR 52.212-3, Offeror Representations and Certifications - Commercial Items (DEC 2014), with its offer or acknowledge its listing in the System for Award Management (SAM) website. (xi) The clause at FAR 52.212-4, Contract Terms and Conditions - Commercial Items (DEC 2014), applies to this acquisition. (xii) The clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders -- Commercial Items (May 2015), applies to this acquisition. The Contracting Officer has indicated the following clauses listed in paragraph (b) as applicable and are hereby incorporated by reference: (4) 52.204-10, Reporting Executive Compensation and First-Tier Subcontract Awards (JUL 2013); (8) 52.209-6, Protecting the Government's Interest When Subcontracting with Contractors Debarred, Suspended, or Proposed for Debarment (AUG 2013); (25) 52.222-3, Convict Labor (JUN 2003); (27) 52.222-21, Prohibition of Segregated Facilities (FEB 1999); (28) 52.222-26, Equal Opportunity (MAR 2007); (30) 52.222-36, Equal Opportunity for Workers with Disabilities; (39) 52.223-18, Encouraging Contractor Policies to Ban Text Messaging While Driving (AUG 2011); (43) 52.225-13, Restrictions on Certain Foreign Purchases (JUN 2008); and (49) 52.232-33, Payment by Electronic Funds Transfer - System for Award Management (JUL 2013). (xiii) Brand Name Justification The US Department of Health and Human Services (DHHS), Office of the Secretary (OS), Assistant Secretary for Administration (ASA), Office of the Chief Information Officer (OCIO), has a need to renew its annual maintenance subscription for RSA software and tokens. RSA Tokens are used for two-factor authentication in the OS network environment for systems that cannot use PIV card authentication. RSA authentication is already being used within OS infrastructure and is compatible with TIC'S systems, Federal Information Security Management Act (FISMA) policies, standards, and mandates, and Office of Management and Budget (OMB) requirements. RSA license is brand specific and only RSA brand maintenance may be used; no other brand of maintenance is applicable. (xiv) DPAS - N/A (xv) Quotes are due on July 13, 2015 at 12:00 PM ET, electronically to the attention of Zipora Chepkoit at Zipora.chepkoit@psc.hhs.gov. (xvi) Contact Zipora Chepkoit, Contract Specialist at Zipora.chepkoit@psc.hhs.gov or 301-443-2342 regarding the solicitation. Any inquiries must be emailed to the Contract Specialist, with "OS154232 - Inquiries" in the subject line no later than July 9, 2015 at 12:00PM ET.

CTP Public Education Campaigns Support Services

Department of Health and Human Services, Food and Drug Administration | Published May 5, 2016
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This is a PRE-SOLICITATION NOTICE to announce the anticipated release of the solicitation for CTP Public Education Campaigns Support Services on or about May 20, 2016. This requirement is being competed on a full and open basis. The North American Industry Classification System (NAICS) Code is 541810 - Advertising Agencies. The associated size standard to qualify as a small business under this NAICS code is up to $15 million as measured by total revenues, but excluding funds received in trust for an unaffiliated third party, such as bookings or sales subject to commissions. The commissions received are included in revenues. To reduce the public health burden of tobacco use in the U.S. and educate the public-especially young people-about the dangers of tobacco use, FDA's Center for Tobacco Products (CTP) is developing and implementing a number of public education campaigns. Evidence from controlled field experiments and population studies shows that paid media campaigns are a proven strategy in preventing and reducing population-level tobacco use and have contributed to significant declines in tobacco use over the past several decades. However, the paid media campaigns of today must navigate a dynamic, competitive media environment to find and motivate hard-to-reach audiences who aren't particularly interested in the topic of tobacco to begin with.As a whole, CTP's tobacco public health education campaign program seeks to achieve the following objectives:• Awareness of and receptivity to campaign messages • Increased knowledge of health risks associated with tobacco product use• Increased perceived risks of tobacco product use• Decreased appeal of tobacco products • Reduced susceptibility to tobacco initiation• Pro-health changes in normative beliefs about tobacco product use• Self-efficacy to quit smoking • Increased intention to quit• Decreased intention to initiate The purpose of this acquisition is to provide the FDA Center for Tobacco Products with a mechanism to assist in a full range of activities associated with planning, developing, producing, and delivering consumer-based communication programs, strategies, and materials for multiple multichannel public health education campaigns targeting both national and niche audiences with unique combinations of geographic, demographic, psychographic, socioeconomic, and cultural factors. The Contractor shall provide comprehensive campaign services for multiple public education campaigns targeting audiences as small as 300,000 people to as large as 10 million people, to include, but not limited to, financing and placing media buys up to $70 million.FDA's first national youth tobacco prevention campaign-"The Real Cost"-launched in February 2014. For the first two years, campaign advertising focused solely on at-risk youth ages 12-17 who are open to smoking or already experimenting with cigarettes. In April 2016, FDA expanded "The Real Cost" to include advertising targeted to rural male youth ages 12-17 at risk of smokeless tobacco use. FDA's second youth tobacco prevention campaign-"Fresh Empire"-launched nationally in October 2015 and targets at-risk multicultural (i.e., African American, Hispanic, Asian/Pacific Islander, mixed race) youth ages 12-17 who identify with Hip Hop culture. FDA's most recent tobacco prevention campaign - This Free Life - launched in May 2016 and targets LGBT young adults ages 18-24 who are occasional smokers. The Office is also in the process of developing a tobacco prevention campaign targeting American Indian/Alaska Native youth and a public education campaign to educate adult consumers about the dangers of tobacco products in the point-of-sale environment.The development of campaigns will include detailed market segmentation and the identification of at-risk and underserved populations with regard to tobacco initiation, including risk and protective factors, and tobacco cessation. Unique characteristics, experiences, norms, values, behaviors, and beliefs of targeted audiences, and relevant historical, environmental, and social forces must be taken into consideration in the development and execution of a targeted creative strategy to improve public health.The government requires integration of public education messages across traditional platforms and the use of new media, paid media, partnership, and community-level strategies to achieve the desired effect on intended audiences. An important aspect of campaign communication efforts will be the use of innovative and emerging digital technologies, including mobile, to reach young and diverse audiences. In addition to traditional paid and new media, the government requires community outreach to localize and amplify messages in ways that resonate with intended audiences.Continuing campaign activities will likely include, but are not limited to, complex strategic planning and program management; conducting extensive formative research with target audiences; developing, testing and producing integrated advertising, social media, Web sites and content; planning, negotiating and buying paid media across a range of platforms to ensure the best value to the government; holding local and regional events; developing partnerships with corporations, state and local agencies, federal partners, and non-governmental organizations; working with community-level groups and coalitions; outreach to the entertainment industry; and tracking and evaluating paid media and digital tactics for ongoing, real-time campaign refinement.Pursuant to FAR Parts 15 and 16.5, FDA anticipates the award of a single Indefinite Delivery/Indefinite Quantity (IDIQ) contract allowing for cost plus fixed fee (CPFF) task orders.Small Business Participation will be a weighted evaluation factor for this procurement. The Government will evaluate the extent to which offerors commit and identify small businesses in their proposals. Additionally, small businesses are encouraged to enter teaming arrangements and/or form joint ventures with other small businesses to respond to this solicitation.The Solicitation will be made available on hhtp://www.fbo.gov.Questions or comments MUST be submitted IN WRITING to nicole.stevenson@fda.hhs.gov. NO PHONE CALLS WILL BE ACCEPTED.

Procurement of CISCO Nexus Hardware and Technical Support

Department of Health and Human Services, Program Support Center | Published June 1, 2015  -  Deadline June 5, 2015
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(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is OS152106. (iii) This solicitation and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-82 (iv) The corresponding NAICS code is 423430 (v) List of contract line item number(s) and items, quantities and units of measure Description Quantity Unit Price Total Price Nexus 5596UP, 48 FC transceiver, 48p storage license 2 ONSITE 24X7X4 Nexus 5596UP, 48 FC transceiver , 48p storage 2 Nexus 5500 Storage License, 48 Ports 2 Nexus 5596 Chassis Accessory Kit 2 8 Gbps Fibre Channel SW SFP+, LC 96 Nexus 5500 PS, 1100W, Front to Back Airflow 4 Nexus 5000 Base OS Software Rei6.0(2)N1(2) 2 Power Cord Jumper, C13-C14 Connectors, 2 Meter Length 4 Nexus 5596UP Fan Module 8 Nexus 5500 Unified Mod 16p 10GE Eth/FCoE OR 16p 8/4/2/1G FC 2 1OOOBASE-T SFP 20 Nexus 5500 Module 4 ports QSFP+ 2 40GBASE-CR4 Passive Copper Cable, 5m 2 40GBASE-CR4 Passive Copper Cable, 3m 2 Nexus 5500 Unified Mod 16p 10GE Eth/FCoE OR 16p 8/4/2/1G FC 2 10GBASE-SR SFP Module 20 TOTAL PRICE (vi) Description of Requirement - The Department of Health and Human Services (DHHS), Office of the Secretary (OS), requires hardware to replace End-of-Life hardware in the CISCO Nexus for the Email Environment. This hardware is to upgrade CISCO in the current Information Technology Infrastructure Operations (ITIO) Enterprise Email System environment to ensure a stable and available server infrastructure for ITIO support services. (vii) Delivery and these services are to be for 12 months from award date. (viii) The provision at FAR 52.212-1, Instructions to Offerors - Commercial Items (APR 2014), applies to this acquisition. (ix) The provision at FAR 52.212-2, Evaluation - Commercial Items (OCT 2014), applies to this acquisition. The Government will award a contract resulting from this synopsis/solicitation to the responsible offeror who provides the lowest price and is technically acceptable (LPTA). (x) Offerors are to include a completed copy of the provision at FAR 52.212-3, Offeror Representations and Certifications - Commercial Items (DEC 2014), with its offer or acknowledge its listing in the System for Award Management (SAM) website. (xi) The clause at FAR 52.212-4, Contract Terms and Conditions - Commercial Items (DEC 2014), applies to this acquisition. (xii) The clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders -- Commercial Items (May 2015), applies to this acquisition. The Contracting Officer has indicated the following clauses listed in paragraph (b) as applicable and are hereby incorporated by reference: (4) 52.204-10, Reporting Executive Compensation and First-Tier Subcontract Awards (JUL 2013); (8) 52.209-6, Protecting the Government's Interest When Subcontracting with Contractors Debarred, Suspended, or Proposed for Debarment (AUG 2013); (25) 52.222-3, Convict Labor (JUN 2003); (27) 52.222-21, Prohibition of Segregated Facilities (FEB 1999); (28) 52.222-26, Equal Opportunity (MAR 2007); (30) 52.222-36, Equal Opportunity for Workers with Disabilities; (39) 52.223-18, Encouraging Contractor Policies to Ban Text Messaging While Driving (AUG 2011); (43) 52.225-13, Restrictions on Certain Foreign Purchases (JUN 2008); and (49) 52.232-33, Payment by Electronic Funds Transfer - System for Award Management (JUL 2013). (xiii) Brand Name Justification The Department of Health and Human Services (DHHS), Office of the Secretary (OS), Information Technology Infrastructure Operations (ITIO) has over 600 pieces of Cisco equipment installed throughout the Information Technology Infrastructure (ITI) network (ITIOnet) as well as the HHS backbone network (HHSnet) for network support; network access control devices, routers, switches, etc.. The integration of the network equipment is unified and proprietary to Cisco, hence, the features and/or protocols have been developed by Cisco and the use of non-cisco equipment would not be unified and would require special integration as well as a significant amount of testing and certification before it could be utilized in ITIOnet or HHSnet. Only Cisco equipment meets HHS requirements for a secure network solution. Cisco routers and switches form the foundation of the network infrastructure and they work together to ensure a high level of security, intelligence, and adaptability. Cisco catalyst switches are self-defending, utilizing built-in mechanisms. Security functions are integrated into the infrastructure to help control user access to the network and to various services to help protect against network threats such as worms, viruses, and denial-of-service attacks, and to help ensure privacy in communications. Cisco Catalyst switches offer integrated security solutions for all networks without compromising performance. While Cisco supports industry standards, OS finds it necessary to incorporate several Cisco proprietary features into their networking solutions, including hardware and technical support to meet the requirements of our complex network. (xiv) DPAS - N/A (xv) Quotes are due on June 5, 2015 at 12:00 PM ET, electronically to the attention of Zipora Chepkoit at Zipora.chepkoit@psc.hhs.gov. (xvi) Contact Zipora Chepkoit, Contract Specialist at Zipora.chepkoit@psc.hhs.gov or 301-443-2342 regarding the solicitation. Any inquiries must be emailed to the Contract Specialist, with "OS152106 - Inquiries" in the subject line no later than June 2, 2015 at 3:00PM ET.

Automation Upgrade for Hermes WiScan System

Department of Health and Human Services, National Institutes of Health | Published August 3, 2015  -  Deadline August 18, 2015
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Automation Upgrade for Hermes WiScan System HHS-NIH-NIDA-SSSA-PSOL-15-436 This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. This acquisition is being conducted in accordance with the procedures of FAR Part 13--Simplified Acquisition Procedures, FAR Subpart 13.5--Test Program for Certain Commercial Items, and FAR Part 12--Acquisition of Commercial Items. The solicitation number is HHS-NIH-NIDA-(SSSA)-PSOL-15-436 and the solicitation is issued as a PRE-SOLICITATION, NOTICE OF INTENT, to award a contract on a noncompetitive basis to Idea-Bio Medical LTD, 2 Bergman Rehovot, Israel 007670502. This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13--Simplified Acquisition Procedures, Subpart 13.5--Test Program for Certain Commercial Items, and Subpart 6.302-1, Only one responsible source and no other supplies or services will satisfy agency requirements, and is expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13--Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6--Competition Requirements. The non-competitive determination is based upon the market research conducted as prescribed in FAR Part 10--Market Research, specifically the results of market research concluded no other source of supply or service has access to the proprietary DNA samples that are required in this acquisition. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-80, dated March 2, 2015. The associated NAICS code for this requirement is 333314, Optical Instrument and Lens Manufacturing, size standard 500 employees. The National Institutes of Health National Center for the Advancement of Translational Science performs numerous High Throughput Assays annually. The cumulative experience of NCATS demonstrated a need for a group to consolidate assay development, assay miniaturization applicability and adaptation to evaluate qHTS feasibility, and validation of promising new assay technologies that had previously been done piecewise by different project teams who divided project workflow between data production and these experimental evaluations. The assay development technology laboratory will unburden separate project teams from these tasks, while maintaining full system compatibility with the automated robotic qHTS facility, such that assay development and promising assay technologies can be immediately implemented in large scale drug discovery campaigns with confidence that the assays and novel technology works in the high-density formats used by the qHTS facility. This request is required for this Laboratory in order to develop and deploy new technology and assays for the screening of rare and neglected disease targets. The requirement consists of providing an Automation Upgrade for Hermes WiScan System Project Requirements: Specifically, the NCATS requires the following: 1. AUTOMATION a. IDEA Bio-Medical's Hermes WiScan system is offered with an optional Automation package, enabling the system to work in a robotic environment. The above quotation reflects pricing for the package itself, as well as for software and hardware integration support to enable system compatibility with a robotic environment: b. Automation package: i. - Remote accessibility ii. o Protocols (applications and screening parameters) execution and management iii. - External loader compatibility (robot/manipulator) 1. Communication channel for control by external equipment 2. Loading door with automatic opening/closing synchronized with external equipment 3. Nest compatibility iv. - External loader (robot/manipulator) integration 1. Full integration support (does not include drivers, only APIs) 2. Driver Development a. - Development of API wrapper (local driver) to integrate with external scheduler b. - Implementation of customer automation protocol c. - Automation protocol tester for preliminary remote integration d. - Integration of automation protocol with Hermes driver e. - Robotic arm protocol development f. - Robotic arm protocol integration and testing g. - Full system integration and testing 3. Robotic Integration - Enabling robotic arm access to Hermes WiScan system for plate loading and unloading - Designing robotic arm movement and plate control - External stage for plate positioning - Integrating robotic arm into robot configuration - Testing and adjusting for optimal performance 4. OBJECT MAPPING Enhances throughput of high magnification screens by enabeling recognition of islands of interest in low magnification (using automatic image analysis to recognize the features of interest), and imaging of those islands in higher magnification. The objects of interest are detected based on their features as detected at the low magnification image and are imaged using the high magnification objective. The object mapping package includes also automatic objective exchanger for up to 3 objectives. This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Respondents that believe that they are manufacturers or authorized resellers of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order. The following FAR provisions shall apply to this solicitation: 52.212-1, Instructions to Offerors--Commercial Items, 52.212-2, Evaluation--Commercial Items. Evaluation factors that will be used to evaluate the offer most advantageous to the Government, price and other factors considered, include ability to meet the technical requirements stated in this pre-solicitation and on basis of best value to the government. Offerors must include a completed copy of the provision at 52.212-3, Offeror Representations and Certifications Commercial Items, with their offer. The Clause at 52.212-4, Contract Terms and Conditions Commercial Items, applies to this acquisition and the Clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items applies to this acquisition. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency. All responses must be received by August 18, 2014 at 4:00 pm, Eastern Standard Time (EST) and must reference solicitation number HHS-NIH-NIDA-SSSA-PSOL-15-436. Responses may be submitted electronically to amcgee@mail.nih.gov and to NIDASSSAPurchaseRequ@mail.nih.gov or by U.S. mail to the National Institute of Drug Abuse (NIDA), Station Support / Simplified Acquisition Branch (SS/SA), 31 Center Drive, Building 31, Room 1B59, Bethesda, Maryland 20892-2080, Attention: Andrea McGee. Fax responses will be accepted at (301) 480-1358. For information regarding this solicitation, contact Andrea McGee by email at amcgee@mail.nih.gov or by phone at (301) 435-8781.

Social Media Outreach to Balck and Latino Community

Department of Health and Human Services, Program Support Center | Published August 11, 2015  -  Deadline August 26, 2015
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Notice of Intent to Sole Source: Pursuant to the authority of FAR 13.106-1(b)(1)(i), the Contracting Officer may solicit from one source if the Contracting Officer determines that the circumstances of the contract action deem only one source is reasonably available. The Department of Health and Human Services (DHHS), Program Support Center (PSC), Acquisition Management Services (AMS) on behalf of PSC, Substance Abuse and Mental Health Services Administration (SAMHSA) intends to sole source to: BlackDoctor.org 116 W. Illinois St. 3rd Floor Chicago, Illinois 60610 The Substance Abuse and Mental Health Services Administration (SAMHSA) is interested in contracting with BlackDoctor.org to develop a communication strategy and evidence-based messages that are culturally competent and relevant to African-American and Hispanic/Latino minority communities. In today's communication and social media environment cultural and linguistic social media messages impact people of color when language, images, messages and medium are consistent with the worldview and culture of the audience. These developed communication models and associated messages such as blogs, drop-in articles, tweets and best practices for engagement will be maintained in a library that will be disseminated across State Mental Health authorities. State Mental Health authorities and their provider communities can use these communication strategies and messages to increase mental health literacy, accessing care and information about recovery, resiliency, peer/family support and prevention strategies that are culturally competent. BlackDoctor.org (BDO) is the world's largest and most comprehensive online health resource specifically targeted to African Americans with a monthly reach of 15.5 million. BDO's mission is to provide and be a trusted, daily resource for healthier, happier living, and daily medicine for life. BDO understands that the uniqueness of Black culture - heritage and tradition - plays a role in their health. BDO recognizes the challenges, barriers and disparities, the African American community experiences with accessing and receiving health and behavioral health care services and treatment. It provides an online resource and tools for African-Americans accessibility to innovative new approaches to the health information needed in everyday language. Their resources include health news and features on the latest health topics and tips; nearly 100 health channels; community blogs from health writers and doctors; and searchable directory of doctors, primary care physicians, and specialist. Additionally, it provides essential, but difficult to find, health resources for families, including free referrals to top Black physicians and health articles that focus on both culturally accurate content and general health topics. BlackDoctor.org launched LatinoDoctors.org in 2014 which serves as a crucial resource that provides similar services for the Hispanic/Latino community. LatinoDoctors.org, now DailyVitamina.org, is similar to BDO, having the same mission of providing culturally competent and linguistic relevant comprehensive health information to the Hispanic/Latino community. Their website, social media, and daily news stories are distributed to over 100 health channels in both English and Spanish. BDO has multiple outlets to reach its audience from an online Daily Newsletter with over 350,000 opt-in subscribers and over 12.1 million Facebook followers. In 2013, Blackdoctors.org partnered with SAMHSA during Recovery Month, producing Facebook messages reaching over 687,000 people of which 3,234 clicked through to healthcare.gov. Their four national recovery month tweets reached over 9,000 BDO followers. BDO's expertise has been recognized through various awards and recognitions to includes the 2006 Web Award for Health Care Standard of Excellence; being featured in multiple publications across the nation, including The New York Times, Washington Post, USA Today, Atlanta Constitution, Dallas News, Self Magazine and Jet Magazine and its strategic partnerships with the National Medical Association and the National Black Church Initiative The above experience and reach demonstrates that BlackDoctor.org is the only company capable of researching and creating effective web-based messages around behavioral health literacy, accessing care and information about recovery, resiliency, peer/family support and prevention strategies that are culturally competent. They have the necessary resources and relationships within the African-American and Hispanic/Latino communities to fulfill. This is not a solicitation for competitive proposal. No solicitation document is available. All responsible sources that have determined that they can provide the same services may submit product information and a capabilities statement addressing their specific abilities regarding this requirement. The email subject line must reference SAM156095. All responses are due by August 26, 2015, 8:00 AM Eastern Time and can be sent to Flora Gomes at flora.gomes@psc.hhs.gov. A determination by the Government not to compete this proposed contract base upon responses to this notice is solely within the discretion of the government.

Bromium Annual Maintenance

Department of Health and Human Services, Program Support Center | Published April 8, 2015  -  Deadline April 13, 2015
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(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is OS150950. (iii) This solicitation and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-80. (iv) This is a Small Business Set Aside. The corresponding NAICS code is 511210 with a size standard of $38.5M. (v) List of contract line item number(s) and items, quantities and units of measure: Period of Performance- 6/1/2015-5/31/2016 Quantity Description 250 Bromium vSentry Annual Maintenance 1 Bromium LAVA 5000 Annual Maintenance (vi) Description of Requirements - Bromium Annual Maintenance (vii) Delivery and all services are to be no later than 30 days after the issuance of award. Please see shipping locations for a listing of cities where units are to be shipped along with quantities. (viii) The provision at FAR 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition (ix) The Government will award a contract resulting from this synopsis/solicitation to the responsible offeror who provides the lowest price and is technically acceptable. (LPTA). (x) Offerors are to include a completed copy of the provision at FAR 52.212-3, Offeror Representations and Certifications - Commercial Items, with its offer or acknowledge its listing in Online Representations and Certifications Application (ORCA). (xi) The clause at FAR 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. (xii) The clauses at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items, Alternate II, applies to this acquisition. The Contracting Officer has indicated the following clauses listed in paragraph (b) as applicable and are hereby incorporated by reference: (1) 52.203-6, Restrictions on Subcontractor Sales to the Government (Sept 2006), with Alternate I (Oct 1995) (41 U.S.C. 253g and 10 U.S.C. 2402); (4) 52.204-10, Reporting Executive Compensation and First-Tier Subcontract Awards (Jul 2010) (Pub. L. 109-282) (31 U.S.C. 6101 note); (6) 52.209-6, Protecting the Government's Interest When Subcontracting with Contractors Debarred, Suspended, or Proposed for Debarment. (Dec 2010) (31 U.S.C. 6101 note); (8) 52.209-10, Prohibition on Contracting with Inverted Domestic Corporations (section 740 of Division C of Pub. L. 111-117, section 743 of Division D of Pub. L. 111-8, and section 745 of Division D of Pub. L. 110-161). (19) 52.219-28; (26) 52.222-3, Convict Labor (June 2003) (E.O. 11755); (27) 52.222-19, Child Labor-Cooperation with Authorities and Remedies (Jul 2010) (E.O. 13126); (28) 52.222-21, Prohibition of Segregated Facilities (Feb 1999); (29) 52.222-26, Equal Opportunity (Mar 2007) (E.O. 11246); (30) 52.222-35, Equal Opportunity Veterans; (31) 52.222-36, Affirmative Action for Workers with Disabilities (Jun 1998) (29 U.S.C. 793); (32) 52.222-37, Employment Reports on Veterans; (38) 52.223-18, Encouraging Contractor Policies to Ban Text Messaging While Driving (AUG 2011) (E.O. 13513). 39) 52.225-1, Buy American Act-Supplies (Feb 2009) (41 U.S.C. 10a-10d). (42) 52.225-13, Restrictions on Certain Foreign Purchases (June 2008) (E.O.'s, proclamations, and statutes administered by the Office of Foreign Assets Control of the Department of the Treasury); (47) 52.232-33, Payment by Electronic Funds Transfer-Central Contractor Registration (Oct 2003) (31 U.S.C. 3332). (50) 52.239-1, Privacy or Security Safeguards (Aug 1996) (5 U.S.C. 552a). (xv) Brand Justification: Bromium vSentry software creates a specific environment isolated down to the hardware which mimics a singular system which prevents the malware from escaping. The software provides a micro virtualization (also referred to as a hardware isolation virtualization) capability which uses hardware level isolation to stop targeted attacks including zero day exploits, commonly considered undetectable, from successfully penetrating Department systems. The software utilizes micro-virtualization for the most common untrusted tasks and threat vectors, including browsing the internet, downloading documents, opening email attachments, and launching files from authorized USB/removable storage devices. This software is currently in use by the Department and a transition to another system could cause a loss or damage to data. (xvi) DPAS - N/A (xvii) Quotes are due Monday, April 13, 2015, 10:00 AM Eastern Time, electronically to the Contract Specialist at Robert.Bowman@psc.hhs.gov. Late quotes will not be accepted. (xviii) Contact Mr. Robert Bowman, Contract Specialist, at Robert.Bowman@psc.hhs.gov regarding the solicitation. Any inquiries must be emailed to the Contract Specialist, with "OS150950- Inquiries" in the subject line, no later than 2 PM Eastern Time on Thursday, April 9, 2014.

Assays

Department of Health and Human Services, National Institutes of Health | Published May 29, 2015  -  Deadline June 9, 2015
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SOLICITATION NUMBER: HHS-NIH-NIDA-SSSA-NOI-15-284 TITLE: Assays INTRODUCTION This is a pre-solicitation non-competitive (notice of intent) synopsis to award a contract without providing for full or open competition (including brand-name). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL. A SOLICITATION WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institute on Drug Abuse (NIDA), Consolidated Station Support and Simplified Acquisitions (CSS/SA) Branch intends to negotiate and award a purchase order to CISBIO USA for small molecules without providing for full and open competition (including brand-name). NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE This acquisition is unrestricted. The associated NAICS code 325414 with a size standard of 500 employees. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the through Federal Acquisition Circular (FAC) 2005-80 effective April 10, 2015. This acquisition is for a commercial item or service and is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures. This acquisition is NOT expected to exceed the simplified acquisition threshold. STATUTORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1. DESCRIPTION OF REQUIREMENT Purpose and Objectives: The purpose of this requirement is to acquire the purchase of proprietary custom antibodies, buffers, and blocking reagents required for our approved assay project. Project Description: The Tox21 group of National Center for Advancing Translational Sciences (NCATS), Division of Preclinical Innovation (DPI) requires a reagent named "HTRF® Phospho-H2A.X (S139) Assay" to run H2A.X assay against Tox21 Library collections. This will be used to screen the Tox21 10K library with an assay for DNA damage. The assay works by detecting the phosphorylation of histone H2AX by labeling antibodies with donor and acceptor fluors (europium cryptate and d2) to enable homogenous detection in a high throughput environment using Cisbio's HTRF technology. Currently, the only technology available for pH2AX detection is immunofluorescence, which requires many incubation and wash steps. HTRF® is a homogeneous and non radio-isotopic technology. This HTRF technology has been developed and also successfully used for our online validation for this homogenous (no wash steps) DNA damage detection assay that was just approved by our review group. When DNA double strand breaks occur, histone H2AX is phosphorylated and moves to the site of the damage. This assay will be used to CHO cells as a marker for DNA damage. Homogenous assays, like HTRF, are key to efficient and effective screening. Our Tox21 research group, as well as other NCATS Biology groups, has used this Cisbio HTRF technology for several large screens in 1536 well format, with high reproducibility and low false positives, compared to other technologies. For example, the HTRF TNF alpha assay was used to screen the LOPAC and FDA libraries in 1536 well format with great success. We will use this assay to screen compounds from EPA/NTP/FDA. This is the Tox21 collaboration work between NCGC and NTP/EPA/FDA. Specifically, NCATS requires the following: Histone2 HTRF assay 10K tests Qty. 10 Delivery/Period of Performance: 30 Days ARO CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME) DETERMINATION The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted. Specifically, CISBIO is the only vendor in the current market place that can provide the unique services required by the of National Center for Advancing Translational Sciences. In accordance with FAR part 10, extensive market research was conducted to reach this determination. Specifically, a small business sources sought notice was posted to FedBizOpps referencing the above detailed requirements and no responses were received. Therefore, only CISBIO USA is capable of meeting the needs of this requirement. The intended source is: Cisbio USA 135 South Road Bedford, MA 01730 CLOSING STATEMENT THIS SYNOPSIS IS NOT A REQUEST FOR COMPETITIVE PROPOSALS. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses shall be submitted no later than June 9, 2015 at 4:30pm EST. Responses may be submitted electronically to amcgee@nih.gov or by U.S. mail to the National Institute of Drug Abuse (NIDA), Station Support / Simplified Acquisition Branch (SS/SA), Attention: Andrea McGee. Fax responses will not be accepted.

Qty of 2 - LNX-EP-100-M1 LiveNX Enterprise 100 Support with 1 Year Maintenance and Qty of 2 - LNX-EP-25-M1 LiveNX Enterprise 25 support with 1 Year Maintenance

Department of Health and Human Services, Program Support Center | Published August 8, 2016  -  Deadline August 16, 2016
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(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is OS178600. The solicitation is issued as a Request for Quote (RFQ). (iii) This solicitation and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-78. (iv) The corresponding NAICS code is 511210 and the small business size standard is $38.5 million. (v) List of contract line item number(s) and items, quantities and units of measure - Qty 2 - LNX-EP-100-M1 LiveNX Enterprise 100 Support and Maintenance 1 Year TermQty 2 - LNX-EP-25-M1 LiveNX Enterprise 25 Support and Maintenance 1 Year Term (vi) Description of Requirement - The US Department of Health and Human Services (HHS), Office of the Secretary (OS), Assistant Secretary for Administration (ASA), Office of the Chief Information Officer (OCIO) Information Technology Infrastructure and Operations (ITIO), has a need for Live Action software technical support and software updates. (vii) This (name of requirement) shall be available at the dates below - Base Period: 08/23/2016-08/22/2017 (viii) The provision at FAR 52.212-1, Instructions to Offerors - Commercial Items (APR 2014), applies to this acquisition. (ix) The provision at FAR 52.212-2, Evaluation - Commercial Items (OCT 2014), applies to this acquisition. The Government will award a contract resulting from this synopsis/solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. (x) Offerors are to include a completed copy of the provision at FAR 52.212-3, Offeror Representations and Certifications - Commercial Items (DEC 2014), with its offer or acknowledge its listing in the System for Award Management (SAM) website. (xi) The clause at FAR 52.212-4, Contract Terms and Conditions - Commercial Items (MAY 2015), applies to this acquisition. (xii) The clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items (DEC 2014), applies to this acquisition. The Contracting Officer has indicated the following clauses listed in paragraph (b) as applicable and are hereby incorporated by reference: (4) 52.204-10, Reporting Executive Compensation and First-Tier Subcontract Awards (JUL 2013); (8) 52.209-6, Protecting the Government's Interest When Subcontracting with Contractors Debarred, Suspended, or Proposed for Debarment (AUG 2013); (25) 52.222-3, Convict Labor (JUN 2003); (27) 52.222-21, Prohibition of Segregated Facilities (FEB 1999); (28) 52.222-26, Equal Opportunity (MAR 2007); (30) 52.222-36, Equal Opportunity for Workers with Disabilities; (39) 52.223-18, Encouraging Contractor Policies to Ban Text Messaging While Driving (AUG 2011); (43) 52.225-13, Restrictions on Certain Foreign Purchases (JUN 2008); and (49) 52.232-33, Payment by Electronic Funds Transfer - System for Award Management (JUL 2013). (xiii) Brand Name Justification - The US Department of Health and Human Services (HHS), Office of the Secretary (OS), Assistant Secretary for Administration (ASA), Office of the Chief Information Officer (OCIO) Information Technology Infrastructure and Operations (ITIO), has a need to renew its currently used Live Action software technical support and software updates for the ITIO Network Team in conjunction with the Enterprise Cisco hardware. LiveAction allows ITIO to monitor, adjust, and provide a higher quality of service on the Enterprise Network. LiveAction is the Cisco Intelligent WAN management platform and is used specifically with Cisco Network Equipment. The Enterprise Network in ITIO and HHS-Net all run on Cisco Networking equipment. Live Actio is used specifically with Cisco equipment for Network Performance Management and Quality of Service (QoS) control in our Cisco Enterprise Network. Video conferencing, streaming video presentations, document storage, Email, all take up network bandwidth. In order to properly transmit this traffic, QoS is needed to ensure network bandwidth is made available. Live Action gives us the ability to monitor and provide the bandwidth that is required. This product was previously evaluated against other vendors and products, and was purchased based on meeting the Government's needs. Many other brands were evaluated, discussed, and Live Action was finally selected as the best solution for the Government's needs. ITIO maintains a large Cisco environment not only for their customers but also for the DHHS National Backbone Network. Being able to provide consistent quality of service for Network Traffic is critical to the ITIO mission. (xiv) The clauses at FAR 52.217-9, Option to Extend the Term of the Contract (MAR 2000); FAR 52.232-40, Providing Accelerated Payment to Small Business Subcontractors (DEC 2013); HHSAR 352.203-70, Anti-Lobbying (MAR 2012); and HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity Investigations (JAN 2010), apply to this acquisition. (xv) DPAS - N/A (xvi) Quotes are due on August 16, at 10:00 AM Eastern Standard Time, electronically to the Contract Specialist at azeb.mengistu@psc.hhs.gov. (xvii) Questions regarding the solicitation are due directly to Azeb Mengistu, Contract Specialist, at Azeb.Mengistu@psc.hhs.gov by August 09, 2016 at NOON. Any inquiries must be emailed to the Contract Specialist, with "OS178600 - Inquiries" in the subject line.

High Performance Robotic Workstation for NCATS

Department of Health and Human Services, National Institutes of Health | Published September 10, 2015  -  Deadline September 17, 2015
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High Performance Robotic Workstation for NCATS Competitive Combined Synopsis/Solicitation HHS-NIH-NIDA-SSSA-CSS-15-862 INTRODUCTION This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. This acquisition is being conducted in accordance with the procedures of FAR Part 13--Simplified Acquisition Procedures, FAR Subpart 13.5--Test Program for Certain Commercial Items, and FAR Part 12--Acquisition of Commercial Items. The solicitation number is HHS-NIH-NIDA-SSSA-CSS-15-862 and the solicitation is issued as a request for quotation (RFQ). NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 334516 with a Size Standard of 500 Employees. SET-ASIDE STATUS This acquisition is unrestricted and available for full and open competition. ACQUISITION AUTHORITY This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, FAR Subpart 13.5--Test Program for Certain Commercial Items, and FAR Part 12-Acquisition of Commercial Items, and IS expected to exceed the simplified acquisition threshold. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-84, dated September 3, 2015. The resultant contract will include all applicable provisions and clauses in effect through this date. DESCRIPTION OF REQUIREMENT Background The National Institute of Health (NIH) National Center for the Advancement of Translational Science (NCATS) performs numerous high throughput assays annually and has a need to consolidate assay development, miniaturization applicability, and adaptation. To meet this need, NCATS is creating a facility to provide a collaborative instrumentation resource for NCATS researchers. NCATS requires a high performance robotic workstation to be utilized in this facility. Purpose The purpose of this requirement is acquisition of a high performance robotic workstation to facilitate assay development and technology evaluation projects. The equipment shall be used as a collaborative resource to provide extramural and intramural NCATS researchers with access to assay development support. Project Requirements The NCATS robotic workstation requires one (1) high performance robotic arm with four (4) ambient storage hotels, one (1) incubator and one (1) software scheduler as follows: A. The high performance robotic arm with four ambient storage hotels must meet the following requirements: 1. The robotic arm must offer a 360 degree rotation, 4-axis Selective Compliance Articulated Robot Arm (SCARA) with integrated vision-assisted teaching and barcode reading. 2. The robotic arm must be equipped with a location verification procedure that inspects all nest locations prior to a run and automatically correct minor location discrepancies. 3. The robotic arm must handle most Society for Biomolecular Sciences (SBS) conforming plates in either portrait or landscape orientation and have plate detection during grip. 4. The robotic arm must have an integrated emergency stop and be in accordance with Category 3 safety standards. 5. The robotic arm must have collision detection and recovery and be able to retain control of the plate when the arm loses power. 6. The robotic arm must be able to access microplates via random access storage or via sequential access storage. 7. The robotic arm must have a radius (reach) of at least +/- 597 mm with an overall height of less than or equal to 800 mm and a payload of 250 g. 8. The robotic arm must be able to operate in an environment between 15 °C - 40 °C. 9. The robotic arm must have the proven ability to lid/de-lid plates with stainless steel assay plate lids. 10. The ambient storage hotels must allow random access storage and retrieval for at least 15 plates/hotel. 11. The ambient storage system must allow for expansion with a maximum capacity of 180 plates. 12. The ambient storage hotels must be able to store plates with stainless steel assay plate lids. B. The incubator must meet the following requirements: 1. The incubator must allow storage for up to 280 microplates. 2. The incubator must have an access time of 5 - 9 seconds. This is imperative in high throughput screening as each plate is usually accessed multiple times throughout the course of an assay. 3. The incubator must use a sterilized internal water source and micro particle filter technology to minimize contamination risk. 4. The incubator must have a temperature range of 8 °C - 50 °C with humidity capable up to 98%. 5. The incubator must have a barcode reader that allows for random access storage. 6. The incubator must have a backlit LCD display with read-out messaging and warning alerts should optimum conditions falter. 7. The incubator must have a standard transfer station with a sensor for plate detection. 8. The incubator must have a small access opening to limit temperature fluctuations resulting in excellent temperature stability. 9. The incubator must have the ability to incubate plates with stainless steel assay plate lids. C. The scheduling software must meet the following requirements: 1. The scheduling software must have drivers readily available for over 200 instruments to ensure compatibility with commonly used laboratory equipment. 2. The scheduling software must have the ability to run more than 40 robots or plate movers simultaneously as well as over 50 instruments on a single license. 3. The scheduling software must be able to simulate a run and forecast how long it will take based on batch size within five minutes on a per-step basis and within one hour on a per-run basis. 4. The scheduling software must be able to run continuously for at least a 2 week period without the need for stopping or reinitializing the system. 5. The scheduling software must be able to continuously add plates/new methods to a live running system without pausing the current run. 6. The scheduling software must have robust error monitoring, recovery and control. This includes active deadlock management and resolution capability, operator contact via email/text on system errors and easy to read options for each and every error condition. 7. The scheduling software must include an intuitive graphical drag and drop workflow designer capable of defining processes with variable based decision steps and integrated data events. 8. This scheduling software must provide a common teach environment that supports multiple robots from multiple vendors which means unlimited potential for upgrades and expansion. 9. The scheduling software must have the ability to schedule variable based decision steps and integrate data events that would induce a dynamic change to the workflow. 10. The scheduling software must contain a software developer's kit that allows users to integrate new instruments and support complete systems with standardized software and hardware tools. 11. The scheduling software must allow the user to run multiple methods simultaneously and interleave the methods for most efficient use of instruments and throughput of samples. 12. The scheduling software must have "attended" and "un-attended" operation modes, which provides situation dependent automatic responses to continue the run in case of missing sample, barcodes and instrument failures. Delivery Requirements/Period of Performance The Contractor shall deliver and install the required equipment within ninety (90) days after receipt of order. Delivery shall be on a F.O.B Destination basis. The equipment shall be delivered between the hours of 8:00 AM to 5:00 PM, Rockville, MD local prevailing time, Monday through Friday. Contract Type The Government intends to issue a firm fixed price contract for this requirement. Invoicing shall be on a NET30 basis after goods are accepted. Milestone invoicing may be considered. Question and Answer Period Interested contractors may submit questions relating to this requirement. Questions shall be submitted to the contract specialist, Lauren Phelps, via email at lauren.phelps@nih.gov by or before 09/14/2015 at 12:00 PM Noon EST. Late questions shall not be accepted. Questions will be anonymized and answered and the answers will be provided as soon as possible after the question deadline via solicitation amendment. Should no questions be received, no amendment shall be posted. APPLICABLE CLAUSES AND PROVISIONS The following FAR clauses and provisions shall apply to this solicitation: 1. All Offerors MUST be actively registered in the System for Award Management (SAM) www.sam.gov. 2. The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items (April 2014), applies to this acquisition. 3. FAR clause 52.212-2, Evaluation - Commercial Items (October 2014) applies to this acquisition. 4. A completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items (March 2015), is required with any offer submitted. This requirement may be met by completion of the provision in the System for Award Management. 5. FAR clauses 52.212-4, Contract Terms and Conditions - Commercial Items (May 2015) and 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items (May 2015) apply to this acquisition. 6. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. In addition, the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." EVALUATION CRITERIA FAR clause 52.212-2, Evaluation - Commercial Items applies to this acquisition and the specific evaluation criteria to be included in paragraph (a) of that provision are as follows: The Government will award a contract resulting from this solicitation on the basis of lowest price technically acceptable. Technical acceptability shall be based on the following: 1. The Contractor must meet or exceed each of the project requirements detailed in this solicitation. 2. The Contractor must be able to meet or exceed the delivery schedule requirement (delivery and installation within 90 days or less). RESPONSE FORMAT Responses to this solicitation must include clear and convincing evidence of the offeror's capability of fulfilling the requirement as it relates to the technical evaluation criteria. The offeror must submit 1) a technical response and 2) a separate price quotation. The technical response should be prepared in reference to the evaluation criteria identified in this solicitation and may be up to twenty single-sided pages. The price quotation must include the requirements listed above as well as associated pricing. Contractors must provide their Company Name, Dun & Bradstreet Number (DUNS), Taxpayer Identification Number (TIN), Business Size, Physical Address, and Point of Contact Information in their responses. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." NOTE Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. CLOSING STATEMENT All responses must be received by the closing date of this announcement and must reference solicitation number HHS-NIH-NIDA-SSSA-CSS-15-862. Responses shall be submitted electronically via email to Lauren Phelps, Contract Specialist, at lauren.phelps@nih.gov.

Thermo Matrix 2D barcoded tubes

Department of Health and Human Services, National Institutes of Health | Published August 17, 2015  -  Deadline August 31, 2015
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Thermo Matrix 2D barcoded tubes HHS-NIH-NIDA-SSSA-PSOL-15-600 This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. This acquisition is being conducted in accordance with the procedures of FAR Part 13--Simplified Acquisition Procedures, FAR Subpart 13.5--Test Program for Certain Commercial Items, and FAR Part 12--Acquisition of Commercial Items. The solicitation number is HHS-NIH-NIDA-(SSSA)-PSOL-15-600 and the solicitation is issued as a PRE-SOLICITATION, NOTICE OF INTENT, to award a contract on a noncompetitive basis Nalge NUNC International, 75 Panorama Creek Drive, Rochester, NY 14625. This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13--Simplified Acquisition Procedures, Subpart 13.5--Test Program for Certain Commercial Items, and Subpart 6.302-1, Only one responsible source and no other supplies or services will satisfy agency requirements, and is expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13--Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6--Competition Requirements. The non-competitive determination is based upon the market research conducted as prescribed in FAR Part 10--Market Research, specifically the results of market research concluded no other source of supply or service has access to the requirement in this acquisition. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-82, dated August 3, 2015. The associated NAICS code for this requirement is 326160, Plastics Bottle Manufacturing, size standard 500 employees. Project Background: The National Center for Advancing Translational Science (NCATS), part to the National Institutes of Health, works to catalyze innovative methods and technologies that will accelerate bringing diagnostics and therapeutics to patients. The NCATS Therapeutics for Rare and Neglected Diseases (TRND) Section specially focuses on rare and neglected diseases. The NCATS Chemical Genomics Center (NCGC) is tasked with identifying and developing novel small molecule leads against a wide spectrum of human disease targets, which it accomplishes by screening thousands of small molecules in collaboration with both intra-and extramural researchers. A In pursuit of this goal, the Center has a strong internal transdisciplinary team of scientists who continually discover novel small molecules for application against a wide range of human diseases. Discovering probe molecules that could serve as starting points for therapeutics in rare cancers is of great interest within NCATS. NCATS has several projects that address many aspects of oncology mechanisms and approaches to discovering novel, effective small molecules. The services requested here are fee for service testing that will provide insight on efficacy across many cancers and will help progress and provide critical scientific guidance on projects that NCATS has been working on for many years. Purpose and Objectives: The purpose of this acquisition is to provide the National Center for Advancing Translational Sciences (NCATS with bulk barcoded tubes to be used by NCATS Compound Management that stores liquid compound stocks. The Thermo Matrix 2D barcoded tubes (part 3711) are used to store our liquid compound stocks. Each tube is individually barcoded with a unique identifier that can be read by a specialized scanner. Compound Management has developed a system in conjunction with our Analytical Chemistry system around the physical handling and data processing around these Thermo Matrix tubes. The caps (part 4465) are used to seal the tubes and prevent sample leakage and slow the ingress of water and air from entering the tubes. NCATS uses a device called the Tube Auditor to visually determine the volume of sample in each tube. The device takes a picture of the tubes and locates the meniscus. It then uses the predefined settings of that tube to report the volume based on the height of the meniscus. The Tube Auditor can visualize different tube types, but a mixed environment of tubes will prevent an accurate volume determination. Project Requirements: Specifically, the NCATS requires the following: Part no. 4465, CapMat Sepra Seal Preslit Qty 98 Cases Part no. 3711, Tube NS Latch 1.4ml Qty 98 Cases This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Respondents that believe that they are manufacturers or authorized resellers of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order. The following FAR provisions shall apply to this solicitation: 52.212-1, Instructions to Offerors--Commercial Items, 52.212-2, Evaluation--Commercial Items. Evaluation factors that will be used to evaluate the offer most advantageous to the Government, price and other factors considered, include ability to meet the technical requirements stated in this pre-solicitation and on basis of best value to the government. Offerors must include a completed copy of the provision at 52.212-3, Offeror Representations and Certifications Commercial Items, with their offer. The Clause at 52.212-4, Contract Terms and Conditions Commercial Items, applies to this acquisition and the Clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items applies to this acquisition. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency. All responses must be received by August 31, 2015 at 4:00 pm, Eastern Standard Time (EST) and must reference solicitation number HHS-NIH-NIDA-SSSA-PSOL-15-600. Responses may be submitted electronically to amcgee@mail.nih.gov and to NIDASSSAPurchaseRequ@mail.nih.gov or by U.S. mail to the National Institute of Drug Abuse (NIDA), Station Support / Simplified Acquisition Branch (SS/SA), 31 Center Drive, Building 31, Room 1B59, Bethesda, Maryland 20892-2080, Attention: Andrea McGee. Fax responses will be accepted at (301) 480-1358. For information regarding this solicitation, contact Andrea McGee by email at amcgee@mail.nih.gov or by phone at (301) 435-8781.

Procurement of F5-BIG-IP 2000 Series Appliances

Department of Health and Human Services, Program Support Center | Published July 22, 2015  -  Deadline July 27, 2015
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(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is AHR156070 (iii) This solicitation and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-82 (iv) The corresponding NAICS code is 423430 (v) List of contract line item number(s) and items, quantities and units of measure Description of the F5 Networks Units Unit Price Total Price Local Traffic Manager 2000s 8gb Mem F5-BIG-LTM-2000S 2 BIG-IP Service Premium Cat Hw53 F5-SVC-BIG-PRE-HW53 2 BIG-IP Add-On Access Policy Mgr Lics 2000S Base 100 ccu: F5-ADDBIGAPM-2000S-B 2 BIG-IP Service: Premium CAT SW12 F5-SVC-BIG-PRE-SW12-EDI 2 Phone Support Standard Hourly (M-F 8AM-6PM): F5-CST-S 32 BIG-IP TRAINING: Edge Gateway And Access F5-TRG-BIG-EGWAPM 1 Total Price (vi) Description of Requirement - The Department of Health and Human Services (DHHS), Agency of Healthcare for Research and Quality (AHRQ), requires F5-BIG-IP 2000 Series Appliances. AHRQ uses these appliances to build secure, dynamic infrastructures that meet the increasing demands of mobile workers, applications, and network traffic while addressing evolving compliance requirements, and enhancing security of the Enterprise Virtual Desktop Infrastructure (VDI). (vii) Delivery of these services is from 9/01/2015 through 8/31/2016. (viii) The provision at FAR 52.212-1, Instructions to Offerors - Commercial Items (APR 2014), applies to this acquisition. (ix) The provision at FAR 52.212-2, Evaluation - Commercial Items (OCT 2014), applies to this acquisition. The Government will award a contract resulting from this synopsis/solicitation to the responsible offeror who provides the lowest price and is technically acceptable (LPTA). (x) Offerors are to include a completed copy of the provision at FAR 52.212-3, Offeror Representations and Certifications - Commercial Items (DEC 2014), with its offer or acknowledge its listing in the System for Award Management (SAM) website. **Contractor Shall Fill out the Attached Deviation and Return it with any Subsequent Quotes ** Class Deviation to Implement Appropriations Provisions Related to Suspension and Debarment and Tax Delinquencies. ALTERNATE PROVISION: Contractor Tax Liability or Felony Conviction The Consolidated and Further Continuing Appropriations Act, 2015 Pub. L 113-235, Division E, Sections 744 and 745 prohibits covered agencies from using funds to enter into contracts with corporations that have unpaid federal tax delinquencies or certain felony convictions unless certain conditions are met. a. The Offeror represents that - 1. It is [ ] is not [ ] a corporation that was convicted of a felony criminal violation under a Federal or State law within the preceding 24 months. 2. It is [ ] is not [ ] a corporation that has any unpaid Federal tax liability that has been assessed, for which all judicial and administrative remedies have been exhausted or have lapsed, and that is not being paid in a timely manner pursuant to an agreement with the authority responsible for collecting the tax liability. (xi) The clause at FAR 52.212-4, Contract Terms and Conditions - Commercial Items (DEC 2014), applies to this acquisition. (xii) The clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders -- Commercial Items (May 2015), applies to this acquisition. The Contracting Officer has indicated the following clauses listed in paragraph (b) as applicable and are hereby incorporated by reference: (4) 52.204-10, Reporting Executive Compensation and First-Tier Subcontract Awards (JUL 2013); (8) 52.209-6, Protecting the Government's Interest When Subcontracting with Contractors Debarred, Suspended, or Proposed for Debarment (AUG 2013); (25) 52.222-3, Convict Labor (JUN 2003); (27) 52.222-21, Prohibition of Segregated Facilities (FEB 1999); (28) 52.222-26, Equal Opportunity (MAR 2007); (30) 52.222-36, Equal Opportunity for Workers with Disabilities; (39) 52.223-18, Encouraging Contractor Policies to Ban Text Messaging While Driving (AUG 2011); (43) 52.225-13, Restrictions on Certain Foreign Purchases (JUN 2008); and (49) 52.232-33, Payment by Electronic Funds Transfer - System for Award Management (JUL 2013). (xiii) Full Text Clause and Provision (i) FAR 52.203-98, Prohibition on Contracting with Entities that Require Certain Internal Confidentiality Agreements - Representation (FEB 2015) (DEVIATION 2015-02) (a) In accordance with section 743 of Division E, Title VII, of the Consolidated and Further Continuing Resolution Appropriations Act, 2015 (Pub. L. 113-235), Government agencies are not permitted to use funds appropriated (or otherwise made available) under that or any other Act for contracts with an entity that requires employees or subcontractors of such entity seeking to report fraud, waste, or abuse to sign internal confidentiality agreements or statements prohibiting or otherwise restricting such employees or subcontractors from lawfully reporting such waste, fraud, or abuse to a designated investigative or law enforcement representative of a Federal department or agency authorized to receive such information. (b) The prohibition in paragraph (a) of this provision does not contravene requirements applicable to Standard Form 312, Form 4414, or any other form issued by a Federal department or agency governing the nondisclosure of classified information. (c) Representation. By submission of its offer, the Offeror represents that it does not require employees or subcontractors of such entity seeking to report fraud, waste or abuse to sign internal confidentiality agreements or statements prohibiting or otherwise restricting such employees or subcontractors from lawfully reporting such waste, fraud, or abuse to a designated investigative or law enforcement representative of a Federal department or agency authorized to receive such information. (ii) FAR 52.203-99, Prohibition on Contracting with Entities that Require Certain Internal Confidentiality Agreements (FEB 2015) (DEVIATION 2015-02) (a) The Contractor shall not require employees or subcontractors seeking to report fraud, waste, or abuse to sign or comply with internal confidentiality agreements or statements prohibiting or otherwise restricting such employees or subcontractors from lawfully reporting such waste, fraud, or abuse to a designated investigative or law enforcement representative of a Federal department or agency authorized to receive such information. (b) The contractor shall notify employees that the prohibitions and restrictions of any internal confidentiality agreements covered by this clause are no longer in effect. (c) The prohibition in paragraph (a) of this clause does not contravene requirements applicable to Standard Form 312, Form 4414, or any other form issued by a Federal department or agency governing the nondisclosure of classified information. (d)(1) In accordance with section 743 of Division E, Title VII, of the Consolidated and Further Continuing Resolution Appropriations Act, 2015 (Pub. L. 113-235), use of funds appropriated (or otherwise made available) under that or any other Act may be prohibited, if the Government determines that the Contractor is not in compliance with the provisions of this clause. (2) The Government may seek any available remedies in the event the contractor fails to comply with the provisions of this clause. (xiv) Brand Name Justification The Department of Health and Human Services (DHHS), Agency of Healthcare for Research and Quality (AHRQ), uses the F5 BIG IP product to build secure, dynamic infrastructures that meet the increasing demands of mobile workers, applications, and network traffic while addressing evolving compliance requirements, and enhancing security of the Enterprise Virtual Desktop Infrastructure (VDI) F5 BIG IP products and their protection is the preferred solution for Load Balancing and Traffic Management for VMware Horizon View VDI solution that AHRQ using. F5 BIG IP provides continuous updates for product's defenses with the latest software version. The maintenance software is required to update the existing software for bug and security fixes, upgrade, hardware repair, and tech support for existing hardware and software installations. F5 BIG IP provides intelligent load balancing and traffic management as well as advanced application security, acceleration, and optimization. BIG IP consolidates services in one easy to manage device that helps AHRQ simplify system management, scale without disruption, and significantly reduce infrastructure. Utilizing other non-F5 BIG IP brands would create an undue burden and an increased risk on AHRQ and the ability to support the environment. (xv) DPAS - N/A (xvi) Quotes are due on July 27, 2015 at 12:00 PM ET, electronically to the attention of Zipora Chepkoit at Zipora.chepkoit@psc.hhs.gov. (xvii) Contact Zipora Chepkoit, Contract Specialist at Zipora.chepkoit@psc.hhs.gov or 301-443-2342 regarding the solicitation. Any inquiries must be emailed to the Contract Specialist, with "AHR156070- Inquiries" in the subject line no later than July 24, 2015 at 12:00 P.M ET.

ImageXpress Micro Confocal High Content Imaging Systems or Equal

Department of Health and Human Services, National Institutes of Health | Published August 3, 2016  -  Deadline August 31, 2016
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This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is HHS-NIH-NIDA-SSSA-CSS-2016-585 and the solicitation is issued as a Request for Quotation (RFQ). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5- Simplified Procedures for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is expected to exceed the simplified acquisition threshold. (iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-89 dated 07-14-2016.. (iv) The associated NAICS code 334516 and the small business size standard is 1000 . This requirement is full and open with no set aside restrictions. (v) The purpose of this acquisition is to purchase two ImageXpress Micro Confocal High Content Imaging Systems or equal. The Probe Development group is part of The National Center for Advancing Translational Sciences (NCATS). The Probe Development group utilizes 3D bioprinting techniques to generate tissues which will be used to perform studies into causes and treatments of various diseases. This approach can provide data more relevant to the whole body response than traditional studies which use two dimensional cell cultures. Initial research is being performed to advance fabrication techniques and protocols. 3D bioprinting is an additive manufacturing technique to build three dimensional live tissue structures that mimic natural in vitro live tissue. Live cells are harvested and dispensed into spatially controlled patterns in a layer by layer approach to generate three dimensional arrangements. The created structures undergo further biological treatment until they form tissue like morphology. The tissues may subsequently be used for therapeutic and research purposes. As part of the tissue development, verification and testing processes, tissues will be analyzed using High Content Imaging. Tissues take weeks to develop. As a tissue develops, it must be measured and monitored to track its development and record any relevant data. In order to measure fluorescence and colorimetric data in tissues, we require a High Content Imaging System. After tissue development, tissues will be screened for response to drugs. The High Content Imaging System will be essential to efficiently obtain data from our screens, and provide results from our assays (vi) ImageXpress Micro Confocal High Content Imaging System.The systems must meet the following requirements in order to achieve the results desired in accordance with the programs mission.o ImageXpress Micro Confocal High Content Screening System which includes: 10X Plan Apo 0.5 NA objective, MetaXpress Imaging and Analysis software, Windows 7 64-Bit Acquisition computer with MDCStore database and Microsoft SQL Express (10GB size-limited database), Toolkit with slide holder and bead plate 1 year warranty covering parts & labor. o ImageXpress Confocal Research Option. Includes: 8 position filter wheel, 5 position dichroc wheel, dual disk unit allowing selection between 3 modes of A) 60 micron pinhole disk for your basic confocal requirements B) 42 micron pinhole disk for high resolution confocal imaging) and C) widefield (not-confocal) imaging mode.o IMAGEXPRESS MICRO CONFOCAL: ENVIRONMENT CONTROL AND TRANSMITTED LIGHT WITH PHASE CONTRAST COMBINATION, 120VAC Includes: 20x Ph1 S Plan Fluor ELWD ADM 0.45 NA Objective.o 27 INCH Monitor; 2560 X 1140 with >3 USB PORTs and multiple video INPUTSo STANDARD, MICROSOFT SQL SERVER, 64 Bit License. Includes Licensing for 5 Device CAL ( Client Access License) Pleas refer to the attachjed statement of work for the complete details and required specifications. (vii) The units are to be delivered and installed within 4 months from the date of receipt of the executed award. (viii) The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition.   Any response to this solicitation\synopsis must include the offerors ability to meet or exceed the specified requirements in addition to the fully satisfying the mandatory requirements and the delivery and installation schedule. (ix) The provision at FAR clause 52.212-2, Evaluation - Commercial Items, applies to this acquisition. (a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate offers: Mandatory CriteriaThe system must have the following features and capabilities;1. Multiple confocal disk geometries including a high-resolution dual disk configuration with 60 micron confocal pinhole, 42 micron confocal pinhole and widefield modes. It must be upgradeable to include a 50 micron slit confocal mode. This allows us to select disc geometry to match resolution and speed needs.2. Be available with objectives ranging in magnification from 1x-100x to allow us to conduct a wide range of studies. 3. Have optically encoded resolution of at least 100nm to achieve high accuracy and precision in X, Y, and Z axes.4. Have high contrast, hardware based (instead of digital) brightfield and true phase contrast imaging, including 0.3 NA with 65 mm WD and PhL, Ph1, and Ph2 selectable phase rings. This will allow us to image non-fluorescent histochemically stained samples, as well as localize fluorescent signal to cellular morphology and therefore compare fluorophore-independent morphology with fluorescent image overlay.5. Have a solid state light engine to provide an expected lifetime of 20,000 hours.6. Conduct both fluorescence and colorimetric imaging.7. Have a footprint no larger than 21" W x 34" L x 19" H, to fit the space allotted. Technical Evaluation CriteriaTechnical Capabilities - The proposed equipment capabilities to meet or exceed the specifications stated in the statement of work .Past Performance - Contractor must demonstrate their ability to deliver and maintain the units proposed. Vendors should provide 3 references for units that have been delivered, installed and currently are being maintained for the past three years. Delivery Schedule - Must be able to meet or exceed the delivery time table of 4 months after receipt of award.Technical and past performance, when combined, significantly more important than cost or price; (b) A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer's specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award. (x) The Offerors to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications-Commercial Items, with its offer. (xi) The FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. POST AWARD EVALUATION OF CONTRACTOR PERFORMANCEa. Contractor Performance Evaluations Interim and Final evaluations of Contractor performance will be prepared on this contract in accordance with FAR Subpart 42.15. The Final performance evaluation will be prepared at the time of completion of work. In addition to the Final evaluation, Interim evaluation(s) will be prepared Annually as follows on [Insert Dates]. Interim and Final evaluations will be provided to the Contractor as soon as practicable after completion of the evaluation. The Contractor will be permitted thirty days to review the document and to submit additional information or a rebutting statement. If agreement cannot be reached between the parties, the matter will be referred to an individual one level above the Contracting Officer, whose decision will be final. Copies of the evaluations, Contractor responses, and review comments, if any, will be retained as part of the contract file, and may be used to support future award decisions.b. Electronic Access to Contractor Performance Evaluations Contractors may access evaluations through a secure Web site for review and comment at the following address: http://www.cpars.gov (xii) FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. Refer to attachment number two for the applicable FAR Clauses for this requirement. (xiii) The following additional contract requirement(s) or terms and conditions as determined by the contracting officer are necessary for this acquisition and consistent with customary commercial practices, NONE.(xiv) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. (xv) Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Respondents that believe that they are manufacturers or authorized resellers of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." All responses must be received by August 31, 2016 at 9:00 AM Eastern Standard Time. and reference number HHS-NIH-NIDA-SSSA-CSS-2016-585. Responses may be submitted electronically to Mr. Brian Lind at lindbj@nida.nih.gov. Fax responses will not be accepted. (xvi) The name and telephone number of the individual to contact for information regarding the solicitation Mr. Brian Lind at 301-827-5298.