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Dynamic electrical stimulation of the human brain

Department of Health and Human Services, National Institutes of Health | Published May 11, 2015  -  Deadline May 18, 2015
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INTRODUCTION This is a pre-solicitation non-competitive (notice of intent) synopsis to award a contract without providing for full or open competition (including brand-name). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL. A SOLICITATION WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institute on Drug Abuse (NIDA), Consolidated Station Support and Simplified Acquisitions (CSS/SA) Branch intends to negotiate and award a purchase order Blackrock Microsystems, Inc for a Dynamic Electrical Stimulation of the human brain system with installation and warranty without providing for full and open competition (including brand-name). NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 334510 with a Size Standard of 500 Employees. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 05-72 dated April 15, 2015. This acquisition is conducted under the procedures as prescribed in FAR subpart 12-Acquisition of Commercial Items at an amount exceeding the simplified acquisition threshold ($150,000) and not exceeding $6.5 million. STATUTORY AUTHORITY This acquisition is conducted under the authority of the authority of FAR 6.302-1-Only one responsible source and no other supplies or services will satisfy agency requirements 41 U.S.C. 253(c)(1). DESCRIPTION OF REQUIREMENT Purpose and Objectives The National Institutes of Health (NIH) Clinical Center (CC) is a clinical research hospital providing all medical services for patients participating in human research protocols of the NIH. As part of routine clinical care for neurosurgery patients with epilepsy or brain cancer, we use electrical stimulation of functionally map the brain. We use stimulation to identify brain areas involved in speech, motor, and memory to identify areas to avoid during surgical resection. We are developing techniques to use patterns of stimulation to affect memory and other cognitive functions, which may further guide surgical techniques, and can provide insight into brain function. The Functional and Restorative Neurosurgery Unit is seeking to upgrade its existing neuro-stimulator to allow for precise and dynamic stimulation of multiple brain areas. General Requirements The machine should safely apply electrical stimulation to the human brain. It should interface with the existing clinical EEG monitoring system. Period of Performance Delivery is required within 30 days from notice of award and a one year service agreement. Project Description The Contractor must provide a machine that may performe the following: • physically connect to 96 electrode contacts • stimulate up to 16 contacts at the same time • allow for arbitrary stimulation waveform definition • dynamically switch stimulation waveforms and locations based on computer control • interface with existing electrophysiological recording hardware, the NeuroPort System from Blackrock MicrosystemsInstallation - One year service agreement CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME) DETERMINATION The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted. Specifically, Blackrock Microsystmes, Inc. is the only source capable of meeting the needs of this requirement. There currently are not any other manufacoters that can supply a stimulator in accordance with the required specifications. The intended source is: Blackrock Microsystems 630 Komas Drive, Suite 200 Salt Lake City, UT 84108-1229 CLOSING STATEMENT THIS SYNOPSIS IS NOT A REQUEST FOR COMPETITIVE PROPOSALS. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by the closing date and time of this announcement and must reference the solicitation number. Responses may be submitted electronically to Farrin Stanton, Contract Specialist, at Farrin.Stanton@nih.gov. US Mail and Fax responses will not be accepted

Electrical Stimulation Device

Department of Health and Human Services, National Institutes of Health | Published July 24, 2015  -  Deadline August 4, 2015
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INTRODUCTION This is a combined synopsis/solicitation for commercial items. This announcement constitutes the only solicitation; quotations are being requested and a written solicitation will not be issued. This acquisition is being conducted in accordance with the procedures of FAR Part 13 - Simplified Acquisition Procedures. The solicitation number is HHS-NIH-NIDA-SSSA-CSS-15-662 and the solicitation is issued as a request for quotation (RFQ). NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 334516 with a Size Standard of 500 Employees. SET-ASIDE STATUS This acquisition is not a set-aside and is issued for full and open competition. ACQUISITION AUTHORITY This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures. This acquisition is not expected to exceed the simplified acquisition threshold. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-83, dated July 2, 2015. The resultant purchase order will include all applicable provisions and clauses in effect through this date. DESCRIPTION OF REQUIREMENT Purpose The National Institute of Mental Health, Experimental Therapeutics & Pathophysiology Branch requires an electrical stimulation device for research and development purposes in the newly-forming Clinical Neuromodulation Laboratory in the NIMH. Project Requirements The Contractor must be able to provide a brand name or equal agreement that includes the following: DC Stimulator MC-4 (Quantity: 1) • 4-channel, bi-polar (tDCS, tACS, tRNS, CES, GVS) • 4 x MC Equipment Electrode Set • Panel PC & Control Software • 4 x Independently controllable channels • Current selectable up to 5000μA (5mA) • Freely selectable application duration • Sinusoidal stimulation up to 1000Hz Pair of Rubber Electrodes, custom Sizes or Shapes Customer Defined, Reusable (Quantity: 4) • 2 cm diameter, round MR Upgrade for DC Stimulator MC 4 (Quantity: 1) • MF filter modules • 20m connection cable MR Equipment Electrode Set, MC 4 (Quantity: 1) • 25cm2, apex 5x5cm, reusable • 4 pairs rubber electrodes • Ten20 electrode paste (228g) • 4 electrode cables with RF resistors • 4 rubber head stap sets HD Targets Software for DC Stimulator MC (Quantity: 1) • For goal oriented HD-tDCS • Electrode Connection Box Anticipated Period of Performance This equipment shall be delivered within 4 weeks after receipt of order. Contract Type The Government expects to issue a firm fixed price purchase order for this requirement. APPLICABLE CLAUSES AND PROVISIONS FAR Clause 52.213-4: Terms and Conditions -- Simplified Acquisitions The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. EVALUATION CRITERIA The Government will award a purchase order resulting from this solicitation on the basis of lowest price technically acceptable. Technical acceptability will be evaluated based upon the following: 1. The Offeror must include all the brand name or equal project requirements detailed in this notice in its quotation. 2. If proposing equal equipment, the Offeror must provide specification information for the equipment so that the brand name or equal status may be verified. 3. Technical factors are more important than cost or price. Selection of the contractor to perform this work will be based on the Government's assessment of the best overall value. RESPONSE FORMAT Responses to this solicitation must include clear and convincing evidence of the offeror's capability of fulfilling the requirement as it relates to the technical evaluation criteria. The price quote must include equipment descriptions and specifications per the requirements listed above as well as associated pricing. The quotation must also indicate the trade-in value of the equipment to be traded-in. Contractors must provide their Company Name, Dun & Bradstreet Number (DUNS), Taxpayer Identification Number (TIN), Business Size, Physical Address, and Point of Contact Information in their responses. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." All responses must be received by the closing date of this announcement and must reference solicitation number HHS-NIH-NIDA-SSSA-CSS-15-661. Responses shall be submitted electronically to Jennifer Burns, Contract Specialist, at jennifer.burns2@nih.gov.

A&E Post Design Services for Electrical Vault 11 Transformer and Switchgear Replacement

Department of Health and Human Services, National Institutes of Health | Published October 27, 2015
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Reference Sources Sought Notice that was posted under Reference Number HHS-NIH-ORF-SBSS-15-0001, this pre-solicitation notice provides information with regards to the Office of Research Facilities (ORF), NIH intent to issue a solicitation to WFT Engineers as described in the attached Justification for Other than Full and Open Competition for Post Design Architectural and Engineering Services. The A/E of Record, MW Design, a Joint Venture, was performing Post-Design services under Contract HHSN29220070009I, Order HHSN29200040. MW Design has notified the Government that effective September 30, 2015 MW Design would cease to exist. Hence, the task order was terminated. The ORF Program is seeking a reasonable path to obtain Post Design services immediately or as soon as possible since this complex, technically difficult, multiple phase electrical infrastructure replacement project has been awarded and is underway. Submittals and RFIs have begun to arrive; however, no A/E of Record is available to provide responses. Based on this, the ORF has suspended the construction pending the post design award. It is essential that Post-Design services be continued throughout the construction performance. The project will provide for a continuation of Post Design services, under a new contract, after September 24, 2015.

Electrical Vault 11 Transformer and Switchgear Replacement, ACRF, NIH Bethesda, MD

Department of Health and Human Services, National Institutes of Health | Published May 22, 2015  -  Deadline January 23, 2015
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Link To Document

NIH-LM-2015-350

Department of Health and Human Services, National Institutes of Health | Published March 9, 2015  -  Deadline March 20, 2015
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The objective of this SOW is to acquire Data Center and Server Room Electrical Professional Support Services for the Facility/Infrastructure Support Services, Center for Information Technology (CIT), National Institutes of Health (NIH) and other NIH Institutes and Centers.

General Environmental Services

Department of Health and Human Services, National Institutes of Health | Published April 9, 2016  -  Deadline May 25, 2016
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Multiple Award Indefinite Delivery Indefinite Quantity (MAC IDIQ) The tasks shall require a broad range of technical expertise in a variety of disciplines such as industrial hygiene;toxicology, chemistry; hydrology; meteorology; geology, land use planning, community impact management and development, quality assurance; environmental, chemical, civil, mechanical and electrical engineering, air and noise quality; health and safety, biomedical safety, sociology, economics and others.No telephonic inquiriesSite visit or pre-proposal conference has not yet been setNo incubment contractorWhere applicable, please send suggestions for scope improvement (subject line must include NIHOF2016110)

NIH/RML Library Renovation Project

Department of Health and Human Services, National Institutes of Health | Published September 10, 2015
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The Rocky Mountain Laboratory (RML) requires a remodel of the existing Library in Building A. Building A is housed in the historical "Quad" which consists of Buildings A, 1, 2, 3, 5, 6 and 7. The Quad is a red brick Neoclassic academic style complex of research occupied buildings. The third floor area to be refurbished is approximately 3,940 sf. requires a general modernization from the original 1996 construction. The mission of this Design/Build contract is to accomplish general upgrades, adding in a few key spaces and features, and general rearrangement of work space. Design Objectives include: 1. To use the latest technology to foster collaboration and innovation 2. To design a comfortable, quiet and collaborative working environment for all RML staff 3. To design a number of architectural impact features that draw the RML staff into the new library 4. To create a library that can grow into future needs 5. To bring in as much natural light as possible into the library. This will be accomplished while minimizing the duration and impact of the construction activities to the NIAID program. The mechanical/electrical design philosophy is to rework the existing mechanical system, provide general power, lighting and system adjustments to support the rearrangement. The architectural "impact" features to draw the library patrons into the newly remodeled area include masonry & glass exterior cantilever window area which will include miscellaneous and structural steel. Interior remodel area will include hollow metal doors, metal stud gypsum walls, joint sealants, painting, glass walls, miscellaneous specialties, sound panels, casework, fire sprinkler system adjustments, plumbing/HVAC, BAS upgrades and electrical lighting.

Bruke BioSpin 7T Magnetic Resonance Imaging System, Parallel Receiver Upgrade (II): 12 to 16 Channels

Department of Health and Human Services, National Institutes of Health | Published August 19, 2016  -  Deadline August 23, 2016
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The Laboratory of Functional and Molecular Imaging (LFMI) is in need of an upgrade to a small animal MRI system. The parallel receiver upgrade comprises of 4 additional 1H-only receiver channels for a total of 16 channels. To accommodate the upgrade, the Government will provide one additional console rack in the technical room as part of the site planning. The potential contractor shall verify the configuration of the existing Government-provided HP workstation prior to delivery to confirm that the software is updated recognize the additional receiver channels. The Government shall provide utilities required for the installation and commissioning to include electrical connections, air conditioning, and cooling water. The Laboratory of Functional and Molecular Imaging (LFMI) acquired a small animal 7T/30cm MRI system. The MRI system, comprised of a 7T/30 cm USR magnet and an Avance AV1 electronics. The MRI console came originally equipped with 8 parallel receiver channels that allow simultaneous image acquisition from 8 different RF coils. Having parallel imaging acquisition capability significantly improves on image quality and reduces acquisition time. The receiver was upgraded from 8 channels to 12. This requirement asks for an upgrade from 12 channels to 16.

A&E Services to Renovate Building 10, E-Wing, NIH Bethesda

Department of Health and Human Services, National Institutes of Health | Published March 30, 2015
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This contract is being awarded for Architectural & Engineering Services for pre-design, design and post designservices in support of the E-Wing renovation. The project scope for the E wing renovations includes full interior and systems renovations for new laboratory, lab support, and office facilities on floors 1 through 13, mechanical equipmentrooms on floors 4, 9, 13, and 14, and renovations to provide teaching facilities, administrative support space, and to support MEP systems on floor B2 and B1. Mechanical, electrical, plumbing and laboratory services will come fromcampus supplied central utilities. The entire E Wing will operate on separate systems from the adjacent F wing project scheduled to be completed in two separate phases, respectively (A, B1 and B2 combined).The project will require complete interior demolition of existing vacant building areas, including existing nonstructural walls, finishes, and utilities. The project will also include providing any building infrastructure system necessary to support the full functioning of new use and design. The entire E Wing will operate on separate systems from the adjacent F wing project scheduled to be completedin two separate phases (A, B1 and B2 combined).

3D ASL for General Electric MR-750 3.0T MRI Scanner

Department of Health and Human Services, National Institutes of Health | Published August 5, 2016  -  Deadline August 19, 2016
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INTRODUCTIONTHIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Institute on Drug Abuse (NIDA), Station Support and Simplified Acquisitions (SSSA) Branch intends to solicit by a request for quotation from General Electric Company, GE Healthcare for award on or around August 25, 2016. The purpose of this purchase order will be to provide the National Institute of Mental Health (NIMH) with new software 3D ASL software for the General Electric MR-750 3.0T MRI Scanner. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE and SET ASIDE STATUSThe intended procurement is classified under NAICS code 811310 with a Size Standard of $20.5 Million. This acquisition is NOT set aside for small businesses. REGULATORY AUTHORITYThis acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures. Contracts awarded using FAR Part 13-Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6-Competition Requirements. FAR Subpart 13.106-1 (b) Soliciting from a single source provides that: For purchases not exceeding the simplified acquisition threshold, Contracting officers may solicit from one source IF the contracting officer determines that the circumstances of the contract action deem only one source reasonably available (e.g., urgency, exclusive licensing agreements, brand-name OR industrial mobilization). The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2005-85 dated August 5, 2016. DESCRIPTION OF REQUIREMENTPURPOSE AND OBJECTIVES:This purchase is to provide software to allow the FMRIF 3TC MRI scanner to be able to collect and compute cerebral perfusion maps. Such data will add to that already being collected by researchers engaged in studying patients with a variety of mental conditions, ranging from children with development disorders, to older patients with motion disorders of neural origin, and should enhance understanding of these conditions. PROJECT REQUIREMENTS:The software must run on a General Electric MR-750 3 Tesla MRI scanner, running console software version DV2202. A single option key is required for GE Healthcare system ID 301496MR3T4. From the data collected, the software should compute and display quantitative maps of cerebral perfusion in a human patient. The total scan time should be less than 10 minutes and the software should be capable at providing maps anywhere in the range of 2 mm to 5mm isotropic resolution. The software and the device on which it runs are both FDA approved products, and as such, only GE Healthcare has the knowledge of the hardware and system software to have it certified by the FDA for patient use. CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME) DETERMINATIONThe determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted. Specifically, GE Healthcare, Inc. is the only vendor in the marketplace that can provide the products required by NIMH. In accordance with FAR part 10, extensive market research was conducted to reach this determination. Specifically, a sources sought notice was posted to FedBizOpps referencing the above detailed requirements and no responses were received from other vendors. Additionally, contacts with knowledgeable individuals both in industry and Government, as well as reviews of available product literature, revealed no other sources. Finally, a review of the GSA Advantage, Dynamic Small Business Search, and previous government acquisitions returned no results that meet all of the requirements. Therefore, only GE Healthcare, Inc., is capable of meeting the needs of this requirement. The intended source is:General Electric, GE HealthcareP.O. Box 96483Chicago, IL 60693APPLICABLE TERMS AND CONDITIONS INCORPORATED BY REFERENCE The following FAR clauses and provisions shall apply to this solicitation:1. All Offerors MUST be actively registered in the System for Award Management (SAM) www.sam.gov. 2. The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items (April 2014), applies to this acquisition. 3. A completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items (March 2015), is required with any offer submitted. This requirement may be met by completion of the provision in the System for Award Management. 4. FAR clauses 52.212-4, Contract Terms and Conditions - Commercial Items (May 2015) and 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items (June 2016) apply to this acquisition. 5. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. In addition, the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." CLOSING STATEMENTTHIS SYNOPSIS IS NOT A REQUEST FOR COMPETITIVE PROPOSALS. However, interested parties may identify their interest and capability to respond to this notice. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. All responsible sources may submit a capability statement, proposal, or quotation which shall be considered by the agency. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All responses must be received by the closing date and time of this announcement and must reference the solicitation number, HHS-NIH-NIDA-SSSA-NOI-2016-607. Responses must be submitted electronically to Pamela Daugherty, Contract Specialist, at pamela.daugherty@nih.gov. U.S. Mail and Fax responses will not be accepted.

ACEA Biosciences xCELLigence Real Time Cell Analyzer-DP Bundle

Department of Health and Human Services, National Institutes of Health | Published August 24, 2015  -  Deadline August 31, 2015
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(1) Action Code: Combined Synopsis/Solicitation (2) Date: August 24th, 2015 (3) Year: 2015 (4) Contracting Office Zip Code: 20892 (5) Classification Code: 6640 (6) Contracting Office Address: 6701 Rockledge Drive Rockledge II Bethesda, MD 20892 (7) Subject/Title: ACEA Biosciences xCELLigence Real Time Cell Analyzer-DP Bundle (8) Proposed Solicitation Number: NHLBI-CSB-DE-2015-216-KEW (9) Closing Response Date: August 31st, 2015 (10) Contact Point: Kyle Wisor, Contract Specialist (11) Contract Award and Solicitation Number: TBD (12) Contract Award Dollar Amount: UKN (13) Contract Line Item Number(s): Line Item 1: xCELLigence RTCA-DP Bundle; Line Item 2: Shipping (14) Contractor Award Date: September 9th, 2015 (15) Contractor Name: TBD (16) Description: The National Institutes of Health (NIH), National Institute of Dental and Craniofacial Research (NIDCR), Oral Pharyngeal Cancer Branch (OPCB) is researching therapies for tumor treatments. A tumor vaccine is the one of the most promising therapies for tumor treatment among multiple methods of immunotherapy. The vaccine would activate the tumor-specific immunity without affecting the normal tissues. However, the tumor immunity induced by the tumor vaccine may undergo a process called tumor editing in the tumor microenvironment, where the tumor cells may escape the effects of the vaccine, resulting in low immunogenicity, especially in solid tumors. The regulatory T cell (Treg, a type of white blood cell) is one of the important mechanisms by which tumor editing occurs, and these cells can suppress the immune system by directly contacting tumor-specific cytotoxic T cells or through producing proteins called cytokines. Therefore, inhibiting the functions of Treg cells during tumor vaccine treatment may be the solution to increasing the efficiency of tumor-specific immunity. The NIDCR OPCB requires an ACEA xCELLigence RTCA-DP Bundle to help the labs tumor assays and other adherent cell experiments. (i) "This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued." (ii) The solicitation number is NHLBI-CSB-DE-2015-216-KEW and the solicitation is issued as a request for quote (RFQ). (iii) The solicitation document, the incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-83 effective 03 AUG 2015. (iv) This is a small business set aside. The associated NAICS code is 334118, Computer Terminal and Other Computer Peripheral Equipment Manufacturing, and the small business size standard is 1000 Employees. The acquisition is being conducted in accordance with the procedures of FAR Part 12 and FAR Part 13. (v) The Contractor Requirements are listed below: (vi) The Contractor Shall: 1. The contractor shall provide the ACEA Biosciences xCELLigence RTCA (Real-time Cell Analyzer)-DP Bundle, product number 00380601050, Quantity 1. I. Specifications • RTCA DP Plate Station and Analyzer o Electrical input: +6V DC, 5 W max o Electronic switch resistance: 2-5 ohm o Electrical interface: handling three E-Plate® 16 devices or 3 IM-Plate devices o Communications: RS232 serial communications at a band rate of 57600 bits/second o Environment: 15° C to 40° C, relative humidity: 98% max non-condensing o Output test signal: 22mV rms ± (2% +5 mVrms) @ 10, 25 and 50 kHz o Impedance measure accuracy: ± (2% + 1.5 ohm) o Impedance measurement repeatability: 0.5% o Impedance dynamic range: 5 ohm to 2 kohm o Environment: 5° C to 40° C, Relative humidity: 80% max. up to 31° C decreasing linearly to 50% max at 40° C • RTCA DP Software o User friendly GUI (Graphical User Interface) o Flexible experimental protocol setup o Real-time data acquisition o Real-time numeric and graphic data display o Multiple output formats • RTCA DP WorkStation o Laptop computer capable of running RTCA DP Software (vii) Date of Delivery: Ship upon receipt of the order Place of Delivery: National Institute of Health, NIDCR 30 Convent Drive Building 30, Room 310 Bethesda, MD 20892 (viii) The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. (ix) The provision at FAR clause 52.212-2, Evaluation - Commercial Items, is applicable. The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate offers: Contract award shall be made to the responsible Offeror whose offer, in conforming to this RFQ, provides the overall best value to the Government, technical evaluation factors, and cost considered. The Government's objective is to obtain the highest technical quality considered necessary to achieve the project objectives, with a realistic and reasonable cost. Technical evaluation factors are more important than cost. 1: Technical Criteria (90 points) I. The contractor will be evaluated on the product provided meeting the below specifications: • RTCA DP Plate Station and Analyzer o Electrical input: +6V DC, 5 W max o Electronic switch resistance: 2-5 ohm o Electrical interface: handling three E-Plate® 16 devices or 3 IM-Plate devices o Communications: RS232 serial communications at a band rate of 57600 bits/second o Environment: 15° C to 40° C, relative humidity: 98% max non-condensing o Output test signal: 22mV rms ± (2% +5 mVrms) @ 10, 25 and 50 kHz o Impedance measure accuracy: ± (2% + 1.5 ohm) o Impedance measurement repeatability: 0.5% o Impedance dynamic range: 5 ohm to 2 kohm o Environment: 5° C to 40° C, Relative humidity: 80% max. up to 31° C decreasing linearly to 50% max at 40° C • RTCA DP Software o User friendly GUI (Graphical User Interface) o Flexible experimental protocol setup o Real-time data acquisition o Real-time numeric and graphic data display o Multiple output formats • RTCA DP WorkStation o Laptop computer capable of running RTCA DP Software 2: Price Criteria (10 points) • Price reasonableness: Best Value (x) FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items, is applicable. An offeror shall complete only paragraphs (b) of this provision if the offeror has completed the annual representations and certificates electronically via http://www.acquisition.gov. If an offeror has not completed the annual representations and certifications electronically at the System for Award Management (SAM) website, the offeror shall complete only paragraphs (c) through (p) of this provision. (xi) FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. (xii) FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items, applies to this acquisition. Including the following clauses and Prohibitions: i. 52.223-18, Encouraging Contractor Policies to Ban Text Messaging while Driving (AUG 2011) ii. 52.225-13, Restrictions on Certain Foreign Purchases iii. 52.244-6, Subcontracts for Commercial Items iv. 52.2232-39, Unenforceability of Unauthorized Obligations v. 52.219-6, Notice of Total Small Business Set-Aside vi. 52.222-3, Convict Labor vii. 52.222-19, Child Labor--Cooperation with Authorities and Remedies viii. 52.222-26, Equal Opportunity ix. 52.222-35, Equal Opportunity for Veterans x. 52.222-36, Equal Opportunity for Workers with Disabilities xi. 52.222-37, Employment Reports on Veterans xii. 52.222-50 Combating Trafficking in Persons xiii. 52.232-33, Payment by Electronic Funds Transfer-System for Award Management xiv. 52.222-21, Prohibition of Segregated Facilities (xiii) Additional Contract Requirements: None (xiv) The Defense Priorities and Allocations System (DPAS) and assigned rating are not applicable. (xv) All responses must be received by August 31st, 2015 at 9:00 AM and must reference number NHLBI-CSB-DE-2015-216-KEW. Responses may be submitted electronically to Kyle.Wisor@nih.gov or by U.S. mail to the National Heart, Lung, and Blood Institute, Office of Acquisitions, COAC Services Branch, 6701 Rockledge Drive, Suite 6150B, Bethesda, MD 20892-7902, Attention: Kyle Wisor. Phone: 301-402-3670; Fax responses will not be accepted

Micro-Electrode Recording (MER) system for NINDS Surgical Neurology Branch

Department of Health and Human Services, National Institutes of Health | Published August 18, 2015  -  Deadline August 31, 2015
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Micro-Electrode Recording (MER) system for NINDS Surgical Neurology Branch Competitive Combined Synopsis/Solicitation HHS-NIH-NIDA-SSSA-CSS-15-717 INTRODUCTION This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. This acquisition is being conducted in accordance with the procedures of FAR Part 13--Simplified Acquisition Procedures, FAR Subpart 13.5--Test Program for Certain Commercial Items, and FAR Part 12--Acquisition of Commercial Items. The solicitation number is HHS-NIH-NIDA-SSSA-CSS-15-717 and the solicitation is issued as a request for quotation (RFQ). NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 334516 with a Size Standard of 500 Employees. SET-ASIDE STATUS This acquisition is 100% set-aside for small businesses. ACQUISITION AUTHORITY This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, FAR Subpart 13.5--Test Program for Certain Commercial Items, and FAR Part 12-Acquisition of Commercial Items, and IS expected to exceed the simplified acquisition threshold. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-83, dated August 5, 2015. The resultant contract will include all applicable provisions and clauses in effect through this date. DESCRIPTION OF REQUIREMENT Background The National Institute of Neurological Disorders and Stroke (NINDS) is a part of the National Institutes of Health (NIH), conducting research into the causes, treatment, and prevention of neurological disorders and stroke. The NINDS mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. In agreement with the NINDS mission, the NINDS Surgical Neurology Branch is pursuing research in patients with Parkinson's disease, essential tremor, dystonia, and psychiatric illness who are eligible candidates for Deep Brain Stimulation (DBS) surgery. DBS electrodes are implanted within deep brain structures in these patients in order to address symptoms and micro-electrode recordings are acquired offering novel insight into the circuit mechanisms that underlie learning and decision-making. Purpose The purpose of this requirement is acquisition of one (1) micro-electrode recording (MER) system capable of capturing physiologic activity through multiple channels and capable of providing specific patterns of electrical stimulation. Project Requirements The NINDS Surgical Neurology Branch requires one (1) single micro-electrode recording (MER) system which meets the following requirements: 1. The system must allow for continuous recording of micro-electrode data capable of capturing single-unit spiking and local field potential activity. 2. The system must allow for data recordings from up to ten (five micro-electrode and five local field potential) channels at sampling rates sufficient for the capture of single-unit spiking activity (>20kHZ) 3. The system must also allow for continuous EEG/ECoG and/or EMG recordings through 16 additional channels. The system must also have the ability to be upgraded and expanded up to 64 or 128 channels in the future, if desired in a later requirement. 4. The system must offer integrated impedance measurements of all electrodes. 5. All data from the system, including continuous time raw recordings, spike data, impedance measurements, and recording settings for each recording, must be captured and stored in a permanent file in a Matlab compatible format and labeled in a way that assures proper documentation and attribution to each individual recording session. 6. The system must be capable of streaming data in a Matlab compatible format in real-time to enable real-time analysis of micro-electrode data. 7. The system must provide closed-loop real-time Digital Signal Processing scripting capabilities 8. The system must be capable of providing real-time spike sorting and detection based on configurable templates. 9. The system must include an integrated micro-drive capable of driving up to five micro-electrodes. 10. The system must be capable of providing independent electrical stimulation for separate channels. The system's stimulation unit must allow for simultaneous stimulation on individual channels while preserving recording capability on the remaining channels. 11. The system must allow for configurable and patterned electrical stimulation. Stimulation waveforms must be capable of being programmed. 12. The system must also allow for triggered stimulation to enable closed-loop real-time electrical stimulation. 13. The system must include 16 analog and digital inputs and outputs. 14. The system must include a Leksell frame adapter for compatibility with the Leksell frame (Elekta, Inc.) 15. The system must include sterilization trays for all equipment. 16. The system must include on-site installation, training (8 hours for 4 people), and technical support. The system must also come with unlimited remote support via phone or email for the entire life duration of the device. 17. The system must include a full one year warranty. Delivery Requirements/Period of Performance The Contractor shall deliver (FOB Destination) and install the required equipment within 60 days after receipt of order. The equipment shall be delivered between the hours of 8:00 AM to 5:00 PM, Bethesda, MD local prevailing time, Monday through Friday. Additionally, the contractor shall provide the customer with training on the use of the equipment. Contract Type The Government intends to issue a firm fixed price contract for this requirement. Question and Answer Period Interested contractors may submit questions relating to this requirement. Questions shall be submitted to the contract specialist, Lauren Phelps, via email at lauren.phelps@nih.gov by or before August 21, 2015 at 11:00 AM. Late questions shall not be accepted. Questions will be anonymized and answered and the answers will be provided as soon as possible after the question deadline via solicitation amendment. Should no questions be received, no amendment shall be posted. APPLICABLE CLAUSES AND PROVISIONS The following FAR clauses and provisions shall apply to this solicitation: 1. All Offerors MUST be actively registered in the System for Award Management (SAM) www.sam.gov. 2. The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items (April 2014), applies to this acquisition. 3. A completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items (March 2015), is required with any offer submitted. This requirement may be met by completion of the provision in the System for Award Management. 4. FAR clauses 52.212-4, Contract Terms and Conditions - Commercial Items (May 2015) and 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items (May 2015) apply to this acquisition. 5. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. In addition, the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." EVALUATION CRITERIA FAR clause 52.212-2, Evaluation - Commercial Items applies to this acquisition and the specific evaluation criteria to be included in paragraph (a) of that provision are as follows: The Government will award a contract resulting from this solicitation on the basis of best value, technical factors and price considered. Technical factors together shall be considered more important than price. The technical evaluation factors are as follows, in order of importance: Factor 1: Technical Approach The Offeror shall detail in its technical proposal how it shall meet each of the project requirements. This shall include detailed specifications of the offered equipment and its capabilities. Technical approach shall be evaluated to determine how the proposed equipment meets or exceeds each of the above-detailed requirements. Factor 2: Delivery, Installation, and Training The Offer shall detail in its technical proposal how it shall meet the delivery, installation, and training requirements. The Government shall evaluate for ability to meet or exceed these requirements. Quotations must include a delivery lead time. RESPONSE FORMAT Responses to this solicitation must include clear and convincing evidence of the offeror's capability of fulfilling the requirement as it relates to the technical evaluation criteria. The offeror must submit 1) a technical response and 2) a separate price quotation. The technical response should be prepared in reference to the evaluation criteria identified in this solicitation and may be up to fifteen single-sided pages. The price quotation must include the requirements listed above as well as associated pricing. Contractors must provide their Company Name, Dun & Bradstreet Number (DUNS), Taxpayer Identification Number (TIN), Business Size, Physical Address, and Point of Contact Information in their responses. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." NOTE Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. CLOSING STATEMENT All responses must be received by the closing date of this announcement and must reference solicitation number HHS-NIH-NIDA-SSSA-CSS-15-717. Responses shall be submitted electronically via email to Lauren Phelps, Contract Specialist, at lauren.phelps@nih.gov.

Homogenizer

Other Defense Agencies, Uniformed Services University of the Health Sciences | Published June 12, 2015  -  Deadline June 22, 2015
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The Uniformed Services University of the Health Sciences (USU) is the Nation's federal health sciences university and is committed to excellence in military medicine and public health during peace and war. We provide the Nation with health professionals dedicated to career service in the Department of Defense and the United States Public Health Service and with scientists who serve the common good. We serve the uniformed services and the Nation as an outstanding academic health sciences center with a worldwide perspective for education, research, service, and consultation; we are unique in relating these activities to military medicine, disaster medicine, and military medical readiness. USU is located in Bethesda, MD on the grounds of the Naval Support Activity Bethesda. Additional information regarding USU can be found on our website: www.usuhs.mil. USU has a requirement for a homogenizer to be used for cell lysis (including, E. coli, yeast, insect and mammalian cells) in order to accomplish high protein recovery rates. This is a combined synopsis/solicitation for commercial items in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued. This is a request for quotes (RFQ) for commercial items in accordance with the procedures of FAR Part 12 - Acquisition of Commercial Items and FAR Part 13 - Simplified Acquisition Procedures. This RFQ incorporates all provisions and clauses in effect through Federal Acquisition Circular (FAC) 05-82 (June 8, 2015) and Defense Federal Acquisition Regulation Supplement (DFARS) (June 2, 2015). In order to be eligible for award, offerors must be registered in www.SAM.gov, with completed representations and certifications. Offerors interested in responding to this requirement must provide a quote for a homogenizer , which at a minimum, meets the specifications listed below. A single firm fixed-priced (FFP) order will be awarded. Offerors are encouraged to submit multiple quotes for homogenizers, which will be evaluated separately by the Government. Desired Specifications: DESIRED SPECIFICATIONS Electrical motor is required for power application Stainless steel enclosure required Efficient cooling is required. e.g Heat exchange for product cooling Process a sample as small as ~15mL with flow rates up to 125 ml/min. Flow rate should be independent of pressure The homogenizing pressure should be adjustable between 2068 - 3100 bar 
(30,000 - 45,000 psi). Inlet and outlet temperatures must be able to be controlled by an external heat exchanger. Product temperature limit should not exceed 73ºC (165ºF) Homogenizer sample chamber should be susceptible to sterilization by autoclaving. Suggestive footprint (not to exceed) W x D x H 150 cm x 70 cm x 80cm and weight 170 Kg. Easy to use The Government intends to award a single firm-fixed priced (FFP) purchase order to the offeror representing the best value to the Government based on the evaluation factors listed below. Evaluation factors are listed in order of importance, with most important listed first. The Government will conduct a trade-off between price and non-price factors. The Government is not required to award to the lowest priced offeror or the offeror quoting the highest technically rated item. The Government reserves the right to award without discussions. Evaluation Factors (Listed in order of importance): 1. Technical - Offerors must provide product literature, which demonstrates the capabilities of the quoted item(s). At a minimum the product literature must demonstrate how the quoted item meets the desired specifications outlined above. Information on warranty, and delivery lead-time must be included in the quote submission and will be evaluated. The government reserves the right to utilize technical (i.e, trade magazines) and customer reviews/references as part of the technical evaluation. 2. Price - Offerors must include all applicable costs (Example: Components, Shipping) in their quote. The total quoted pricewill be the evaluated price. In addition to providing product literature, offerors must also submit the completed table below with their quote submission*: DESIRED SPECIFICATIONS QUOTED SPECIFICATION - COMPLETED BY OFFEROR PAGE # SPECIFICATION ADDRESSED IN PRODUCT LITERATURE - COMPLETED BY OFFEROR Electrical motor is required for power application Stainless steel enclosure required Efficient cooling is required. e.g Heat exchange for product cooling Process a sample as small as ~15mL with flow rates up to 125 ml/min. Flow rate should be independent of pressure The homogenizing pressure should be adjustable between 2068 - 3100 bar 
(30,000 - 45,000 psi). Inlet and outlet temperatures must be able to be controlled by an external heat exchanger. Product temperature limit should not exceed 73ºC (165ºF) 170 Kg Homogenizer sample chamber should be susceptible to sterilization by autoclaving. Suggestive footprint (not to exceed) W x D x H 150 cm x 70 cm x 80cm and weight 170 Kg. Easy to use *Offerors who fail to provide the completed chart above, may be considered non-responsive. Offerors must also submit the following with their quote: • Completed copy of provision 252.209-7992 • Completed copy of provision 252.225-7036 See attached list for applicable provisions and clauses for this requirement. Quoted items must be new. Quotes for refurbished equipment will not be considered. Offerors must also indicate in quote where item is manufactured. Items will be shipped to Bethesda, MD. Deadlines: Questions/clarifications regarding this solicitation must be submitted via email to alphonso.simmons@usuhs.edu by June 17, 2015. Any question received after June 9th will not be answered. Questions will not be answered over the phone or submitted by any other means. All questions will be answered in an amendment to the solicitation posted on or around June 18th. Quote packages are due by 10:00 PM Eastern Local Time on June 22, 2015. Quotes must be submitted via email to alphonso.simmons@usuhs.edu. Quotes will not be accepted by any other means. Late quotes will not be considered. Quote packages should include a cover sheet that provides the following information: • Company Name • Point of Contact, to include email and phone number • DUNS Number • Statement that includes acknowledgement of latest amendment number

Sole Source Notice for BetaStar Enviro-Vac Water Pressure Boosters

Other Defense Agencies, Uniformed Services University of the Health Sciences | Published July 9, 2015  -  Deadline July 20, 2015
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The Uniformed Services University of the Health Sciences (USU) is the Nation's federal health sciences university and is committed to excellence in military medicine and public health during peace and war. We provide the Nation with health professionals dedicated to career service in the Department of Defense and the United States Public Health Service and with scientists who serve the common good. We serve the uniformed services and the Nation as an outstanding academic health sciences center with a worldwide perspective for education, research, service, and consultation; we are unique in relating these activities to military medicine, disaster medicine, and military medical readiness. USU is located in Bethesda, MD on the grounds of the Naval Support Activity Bethesda. USU intends to negotiate on a sole source basis with Avant Garde Scientific, Inc. located in Damascus, Maryland for twelve (12) BetaStar Enviro-Vac water pressure boosters and labor to install the units on existing BetaStar LSII autoclaves. This equipment will be procured in accordance with the procedures of FAR Part 12-Commercial Items and FAR Part 13-Simplified Acquisition Procedures. Sole source determination is made in accordance with: FAR 13.106-1 Soliciting Competition (b) Soliciting from a single source (1) For purchases not exceeding the simplified acquisition threshold, contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available. The mission of USU is to provide the highest quality education programs in the health sciences to those selected individuals who demonstrate dedication to a health profession career in the Uniformed Services. As such, it is essential USU provide the necessary training and equipment required for our students to become successful doctors and nurses and to be able to provide the best care possible for our soldiers and to support our research efforts. The BetaStar LS11 Enviro-Vac water pressure booster is the only system available that was specifically designed to be integrated to into the existing plumbing and electrical wiring of the current BetaStar LSII autoclave units. The stainless steel boosters have a thermostatically controlled replenishing system which will correct current water pressure issues that make the units inoperable. Until this is resolved, the autoclaves cannot be used resulting in a significant interruption to research at the University. In addition, the BetaStar booster is the only unit that will fit within the framework of the existing autoclaves. The BetaStar Avant Garde is the exclusive dealer for BetaStar Life Science in Bethesda, Maryland. This is not a request for quotes and a solicitation package will not be issued. Sources interested in responding to this requirement must be able to provide compelling evidence that they can provide the abovementioned requirement as specified. A determination by the government not to compete this proposed contractual action based upon responses received is solely within the discretion of the government. Due to the urgent nature of this requirement responses must be received via email (sherri.ori@usuhs.edu) by 3:00 p.m. EST on July 20, 2015.

Electromyography Testing Machine

Department of Health and Human Services, National Institutes of Health | Published August 31, 2015  -  Deadline September 11, 2015
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Combined Synopsis / Solicitation Title: Electromyography Testing Machine (i) This is a combined synopsis-solicitation for commercial items or services prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is HHS-NIH-NIDA(SSSA)-2015-CSS-709 and the solicitation is issued as a request for proposal (RFP). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5-Test Program for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold. (iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-83, dated August 5, 2015. (iv) A notice regarding any set-aside restrictions, the associated NAICS code 334516 - Analytical Laboratory Instrument Manufacturing (v) Electromyography Testing Machine (vi) Background The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability, conducting, supporting and making medical discoveries that improve people's health and save lives. Purpose The purpose of this requirement is to purchase an Electromyography Testing Machine which will be used in the conduct of the clinical research of the National Institute on Aging Intramural Research Program. Scope of Work Independently and not as an agent of the Federal Government, the contractor shall provide the Electromyography Testing Machine with the following essential features: (1) Desktop Base Computer System that includes Windows 7 Software; (2) Cart, Keyboard, Mouse and mouse pad, and Monitor Arm; (3) Base Unit with 2 channel simultaneous electrical stimulator channels; (4) Operating Software including comprehensive on line report generation via Microsoft Office (including Report Auto Summary), Network Software, One-button click save and upload to common folder Interface feature; (5) Producer Amp Holder with Arm and Post Needle Holder; (6) Power Cord Kit- North American; (7) Control Panel; (8) Amplifier with 2 channel including 2.5 m cable; (9) Comfort probe with electrical stimulator probe including one large angled, one large straight and one touch proof probe head; (10) 19 inch LCD monitor with speakers; (11) Flexible surface temperature probe; (12) Single foot switch; (13) Analog out box; (14) Inject printer with USB cable; and (15) on-site user training. (vii) The Electromyography Testing Machine will be delivered to the National Institute on Aging, 3001 S. Hanover Street, Baltimore, MD 21224. (viii) The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. (ix) The provision at FAR clause 52.212-2, Evaluation - Commercial Items applies to this acquisition. Selection of an Offeror for award will be on the basis of lowest price technically acceptable quote meeting the government's essential features as described herein. The offeror must include all specifications/services (including all brand-name or equal requirements so that the brand-name or equal status may be verified), detailed in this solicitation, in its proposal. Offeror(s) cost/price proposal will be evaluated for reasonableness. For a price to be reasonable, it must represent a price to the Government that a prudent person would pay when consideration is given to prices in the market. Normally, price reasonableness is established through adequate price competition, but may also be determined through cost and price analysis techniques as described in FAR 15.404. The price quoted will be evaluated taking into consideration any price reductions. A best value analysis will be performed taking into consideration the results of the technical evaluation and price evaluation. The Government will award a purchase order resulting from this solicitation on the basis of best value, technical factors and price considered. Technical factors together shall be considered more important than price. (x) The provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items, applies to this acquisition. (xi) FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. An addendum to FAR clause 52.212-4, Contract Terms and Conditions-Commercial Items applies to this acquisition. (xii) FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. (xiii) There are no additional contract requirement(s) or terms and conditions (such as contract financing arrangements or warranty requirements) determined by the contracting officer to be necessary for this acquisition and consistent with customary commercial practices. (xiv) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. (xv) Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. In addition, responses must include clear and convincing evidence of the offeror's capability of fulfilling the requirement as it relates to the salient characteristics. The response should be practical, clear, and concise; should use quantitative terms whenever possible; should avoid qualitative adjectives; and should comprehensively address the requirements of this solicitation. Assumptions, conditions, or exceptions with any of the terms and conditions of this solicitation must be noted. If not noted, the Government will assume that no assumptions, conditions, or exceptions are made and the offeror agrees to comply with all of the terms and conditions as set forth in the solicitation. Information requested herein must be furnished in writing fully and completely in compliance with the solicitation. The information requested and the manner of submittal is essential to permit prompt evaluation of all offers on a fair and uniform basis. Simple statements of compliance (i.e., "understood"; "will comply") or phrases such as "standard procedures will be used" or "well known techniques will be utilized" and other generalities, without the detailed description of how compliance will be met, may not be considered sufficient evidence that the proposal can technically meet the project requirements. Accordingly, any response in which material information requested is not furnished or where indirect or incomplete answers or information are provided may be considered not acceptable. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All questions regarding this combined synopsis/solicitation must be received in this office by 8:00AM (EST) on August 31, 2015. Offers must be received electronically by 12:00 PM (EST) on September 11, 2015. Facsimile submissions are not authorized and collect calls will not be accepted. Please reference the solicitation number HHS-NIH-NIDA-(SSSA)-CSS-15-709 on your offer. (xvi) Requests for information concerning this requirement are to be addressed to Rodney Brooks via e-mail only to rodney.brooks@nih.gov prior to the closing date for questions. Submit offers to: Rodney Brooks, Contract Specialist at rodney.brooks@nih.gov and NIDASSSAPurchaseRequ@mail.nih.gov

Service Contract for PacBio RSII Sequencer System

Department of Health and Human Services, National Institutes of Health | Published April 9, 2015  -  Deadline April 16, 2015
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INTRODUCTION: THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR A PROPOSAL. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Heart, Lung, and Blood Institute (NHLBI) Office of Acquisition (OA) on behalf of the National Human Genome Research Institute, (NHGRI), intends to negotiate and award a purchase order on a non-competitive sole source basis to Pacific Biosciences, 1380 Willow Road, Menlo Park, California 94025 to provide a service contract for a PACBIO RSII SEQUENCER SYSTEM. Background: The National Institute of Health (NIH) mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The National Human Genome Research Institute (NHGRI) mission has expanded to encompass a broad range of studies aimed at understanding the structure and function of the human genome and its role in health and disease. NHGRI supports the development of resources and technology that will accelerate genome research and its application to human health. The National Human Genome Research Institute NHGRI), NIH Intramural Sequencing Center (NISC) is a high-throughput sequencing center supporting all institutes within the NIH. NISC has served the NIH community for over 15 years as a source for high-quality large-scale sequencing and analysis. In addition to providing investigators at the NIH access to large-scale DNA sequencing, NISC plays a major role in several efforts related to the Human Genome Project including a Comparative Vertebrate Sequencing Initiative, the ENCODE Project, and the Mammalian Gene Collection Program. NISC is also an active participant in the International Sequencing Consortium. Purpose and Objectives: The purpose of this sole source solicitation is to procure a service contract for NHGRI/NISC for a Pacific Biosciences Pac Bio RS II Sequencer System. Pacific Biosciences Pac Bio RS II Systems is a Single Molecule, Real-Time (SMRT®) DNA Sequencing System that provides the highest consensus accuracy and longest read lengths of any available sequencing technology. The very long reads produced by the Pacific Biosciences RS II Sequencing System make possible studies of structural variation and repeat content as well as copy number changes, all of which are difficult if not impossible to discern with short read sequence data. The PacBio RS II is therefore a vital component of NISC sequencing production pipeline. It is imperative that the PacBio System is well maintained and operational, in order for NISC's to be completed in a timely fashion and to maintain productivity. Failure of equipment will cause a delay in process down the manufacturing production line and in the delivery of results to customers. Procurement: 1. Standard PacBio RSII System Service Contract, Part Number: 100-236-400, Serial Number: RS42231, Quantity: One (1) Each. Peiod of Performance: 12-Months (June 2015 to June 2016) Contractor's Requirement: • The Contractor shall provide one on-site Preventative Maintenance visit per year. • The Contractor shall provide unlimited on-site emergency visits and up to four applications support visits per year. • The Contractor shall provide Parts and labor coverage for all routine service and maintenance visits. • The Contractor shall provide a Typical response time: 1 business day (remote), 3 business days (on-site). • The Contractor shall provide unlimited phone and email technical support [5am - 5pm Pacific Time, Monday - Friday]. Government Responsibilities: • The Government will follow the operation procedures published by the Contractor, including procedures for routine maintenance. • The Government will maintain the Instrument site in accordance with the Contractor's environmental and electrical site specifications. • The Government will maintain a software release level within one major release of the most current O/S Software release made available by the Contractor. • The Government will not allow repairs, alterations, disassembly, reassembly or removal from facility by persons other than the Contractor or its certified designee. • The Government will adhere that the agreement does not cover service call fees incurred in investigating or remedying any damage or malfunction that results from improper or abnormal use, abuse, neglect, negligence, accident, externally caused short circuits, incorrect voltages, failure or fluctuation of electrical power, lightning, static or other improper external inputs, or Force Majeure. Reporting Requirements and Deliverables • The Contractor shall provide a summary report of their action after a repair and/or preventive maintenance inspection. Inspection and Acceptance Requirements • The Government will accept the job performed by the Contractor. If it is a repair, equipment needs to demonstrate continuous performance. Regulatory Authority: This acquisition is conducted under the authority of 41 U.S.C. 253(c) as set forth in FAR Part 6.302-1, only one responsible source and no other supplies or services will satisfy agency requirements. Additional Information: This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13.106-1(b) Soliciting from a single source, only one responsible source and no other supplies or services will satisfy agency requirements. The acquisition is being conducted under FAR Part 13, simplified acquisition procedures, therefore the requirements of FAR Part 6 B Competitive Requirements are not applicable (FAR Part 6.001). Industry Classification (NAICS) Code is 811219, Other Electronic and Precision Equipment Repair and Maintenance and the Small Business Size Standard is $20.5M. The resultant Contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 05-80 (March 2, 2015). This requirement is under the SAT of $150,000.00. This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by April 16, 2015 and must reference synopsis number HHS-NIH-NHLBI-CSB-(HG)-2015-108-DLM, may be submitted to the National, Heart, Lung and Blood Institute, Office of Acquisition, COAC Services Branch, 6701 Rockledge Drive, Suite 6149, Bethesda, Maryland 20892-7902, Attention: Dorothy Maxwell. Response may be submitted electronically to maxwelld@mail.nih.gov. Faxes will not be accepted. Responses will only be accepted if dated and signed by an authorized company representative. "All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency."

Acquisition of one Brand Name or Equal Autoclave LSII Sterilizer

Department of Health and Human Services, National Institutes of Health | Published August 17, 2016  -  Deadline August 23, 2016
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The NCI/DCEG/Laboratory of Translational Genetics plans to procure a one Brand Name or Equal Autoclave LSII Sterilizer. This is a combined synopsis/solicitation for commercial items, prepared in accordance with format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. This solicitation: No. N02CP62664-57 includes all applicable provisions and clauses in effect through FAR FAC 2005-89 (July 2016) simplified procedures for commercial items. The North American Industry Classification System code is 334516 and the business size standard is 500 employees. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. It has been determined there are no opportunities to acquire green products or services for this procurement. The overall goal of the Laboratory of Translational Genetics (LTG) is to develop new approaches to the study of the genetic basis of cancer and its outcomes. Specifically, LTG is investigating the genetic basis of strong association signals identified in candidate gene association studies, loci identified by linkage analyses in high-risk families, or genome-wide association studies (GWAS). The LTG has an autoclave that is used to preparing media for bacterial cultures, sterilizing water used for cell culture, and sterilizing various other equipment and supplies. This autoclave was installed in the 1980's and has been rebuilt numerous times. At present, the autoclave is not functional at least twice a month. Thus, replacing this aging piece of equipment is expected to save the government money in the long term. I. Description of Contractor RequirementsThe following Salient Characteristics must be provided: 1. Ship and Install the new autoclave with the following minimum requirements:• Cylindrical chamber design - reduces sheer stress on the chamber and increased jacket area decreases heat up time and improves temperature control.• Chamber must be between 250 - 350 L• Manual door, with silicone seal• Free-standing installation with cabinet enclosure panels• Access to the control system, and piping (for service) must be on the right side of the cabinet• Control panel located on the unit, within reach of manual door• Must include these pre-programmed cycles: Pre-vacuum, gravity, liquid, leak test• Quench effluent going to the drain will not exceed 140F.• Water conservation system• Framework must allow for movement of the unit with a pallet jack• Continuous monitoring with alert and alarm identifying any abnormal or unsafe operating condition. Alarm history will be stored for later review• Fail-safe door. Stem supply valve will not allow steam to enter the chamber until the door is fully closed. The door will remain locked to the user until the pressure in the chamber has been fully vented to match the air pressure outside of the chamber.• All electrical components will be positioned to conform to NEC requirements for maintenance access.• Integrated UPS to control voltage spikes, drops and losses 2. Disconnect and remove the existing autoclave (Getinge Castle 122 s/n 98H59452).3. Haul away the old autoclave for proper recycling/disposal.4. Uncrate and inspect the new autoclave. Additional Contractor Requirements:1. The contractor shall be responsible for providing all parts and equipment required for complete installation.2. Move the autoclave from the delivery truck to the final location for operation3. Connect the autoclave to necessary electrical, steam, drains, etc.4. Run a leak test and 2 complete cycles without initiating an error or alarm5. Provide training to end users on the proper operation and safety features of the autoclave (training shall be completed within 14 weeks of contract award).6. Clean up and remove any trash.7. A minimum 12-month warranty must be included in the quote.8. Estimated costs for shipping and installation shall be included in the quote. If such costs are not included, the Government will not be responsible for payment. Government Requirements1. The government will provide the needed electrical, steam and drain sources, as needed by the contractor for this autoclave. Reporting Schedule and Deliverables 1. Drawings for installation and specifications for autoclave shall be completed, and delivered to the COR within 2 weeks after award.2. Drawings shall be reviewed and revised within 2 weeks of receipt.3. Autoclave and all accessories shall be delivered within 10 weeks of approval of drawings. Pre-delivery notification is required. The COR shall be notified at least 72 hours in advance of delivery.4. Installation, testing, and training shall be completed within 2 weeks of delivery. II. Delivery: Contractor(s) shall deliver the item within 30 days after award to the following location: TBA, NIH/NCI 9000 Rockville Pike, Bethesda, Maryland 20892. The Contractor that receives the award will be provided with the complete mailing address and point of contact. Upon delivery, contractor must notify the NCI Contracting Officer's Representative (COR) to schedule the installation date and time.III. Payment: Payment shall be made after delivery, installation, and successful operation of equipment. Payment authorization requires submission and approval of invoice to the NCI COR and NIH Commercial Accounts.QUOTATIONS ARE DUE: August 23, 2016 at 11:00 am EST. PROVISIONS AND CLAUSES: The following FAR provisions and clauses apply to this acquisition: 52.211-6 Brand Name or Equal. (Aug 1999) (a) If an item in this solicitation is identified as "brand name or equal," the purchase description reflects the characteristics and level of quality that will satisfy the Government's needs. The salient physical, functional, or performance characteristics that "equal" products must meet are specified in the solicitation. (b) To be considered for award, offers of "equal" products, including "equal" products of the brand name manufacturer, must- (1) Meet the salient physical, functional, or performance characteristic specified in this solicitation; (2) Clearly identify the item by- (i) Brand name, if any; and (ii) Make or model number; (3) Include descriptive literature such as illustrations, drawings, or a clear reference to previously furnished descriptive data or information available to the Contracting Officer; and (4) Clearly describe any modifications the offeror plans to make in a product to make it conform to the solicitation requirements. Mark any descriptive material to clearly show the modifications. (c) The Contracting Officer will evaluate "equal" products on the basis of information furnished by the offeror or identified in the offer and reasonably available to the Contracting Officer. The Contracting Officer is not responsible for locating or obtaining any information not identified in the offer. (d) Unless the offeror clearly indicates in its offer that the product being offered is an "equal" product, the offeror shall provide the brand name product referenced in the solicitation. (End of provision) HHSAR 352.203-70 ANTI-LOBBYING (MAR 2012) Pursuant to the current HHS annual appropriations act, Public Law 112-74, except for normal and recognized executive-legislative relationships, the Contractor shall not use any HHS contract funds for: (a)Publicity or propaganda purposes;(b)The preparation, distribution, or use of any kit, pamphlet, booklet, publication, electronic communication, radio, television or video presentation designed to support or defeat the enactment of legislation before the Congress or any State or local legislature or legislative body, except in presentation to the Congress or any State or local legislature itself; or designed to support of defeat any proposed or pending regulation, administrative action, or order issued by the executive branch of any State or local government, except in presentation to the executive branch of any State or local government itself; or(c)Payment of salary or expenses of the Contractor, or any agent acting for the Contractor, related to any activity designed to influence the enactment of legislation, appropriations regulation, administrative action, or Executive order proposed or pending before the Congress or any State government, State legislature or local legislature or legislative body, other than for normal and recognized executive-legislative relationships or participation by an agency or officer of a State, local or tribal government is policymaking and administrative processes within the executive branch of that government. The prohibitions in subsections (a), (b), and (c) above shall include any activity to advocate or promote any proposed, pending, or future Federal, State or local tax increase, or any proposed, pending, or future requirement for, or restriction on, any legal consumer product, including its sale or marketing, including, but not limited to, the advocacy or promotion of gun control. 52.212-1 Instruction to Offerors Commercial Items (April 2014) 52.212-2, Evaluation Commercial Items: The purchase order will be awarded to the Lowest Price Technically Acceptable (LPTA). The award will be made on the basis of the lowest evaluated price of quotations meeting or exceeding the acceptability standards for the requirements/technical specifications stated above. The technical evaluation will be a determination based on information furnished by the vendor. The Government is not responsible for locating or securing any information which is not identified in the proposal. The Government reserves the right to make an award without discussions. Full text copies of the representations and certifications for other cited provisions and clauses may be obtained on line at the NCI website at http://ncioa.cancer.gov/oa-internet/reference.jsp or from Reyes Rodriguez, Contracting Officer at reyes.rodriguez@nih.gov . OFFERORS: Offers must be submitted on an SF-1449 with a completed 52.212-3 Offeror Representations and Certifications-Commercial Items-with DUNS Number Addendum, signed by an authorized representative of the offeror OR provide a copy of the valid certification registrations of the offeror's Central Contractor Registration (CCR) and Online Representations and Certifications Applications (ORCA) through www.sam.gov. Quotations must be received in the NCI-OA contracting office by 11:00 a.m. EST on August 23, 2016. Please refer to solicitation number N02CP62664-57 on all correspondence. No collect calls will be accepted. Electronic quotations will be accepted. All questions shall be in writing and may be addressed to the aforementioned individual noted above. No collect calls will be accepted. In order to receive an award, contractors must be registered and have valid certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA) through www.sam.gov. Contracting Office AddressDepartment of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Bethesda, MD 20892, UNITED STATES. Non-USPS mail such as Fedex, UPS and other private carriers please use Rockville, MD 20850.

Service Contract for PacBio RSII Sequencer System

Department of Health and Human Services, National Institutes of Health | Published April 11, 2016  -  Deadline April 18, 2016
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INTRODUCTION: THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR A PROPOSAL. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Heart, Lung, and Blood Institute (NHLBI) Office of Acquisition (OA) on behalf of the National Human Genome Research Institute, (NHGRI), intends to negotiate and award a purchase order without providing full and open competition to Pacific Biosciences, 1380 Willow Road, Menlo Park, California 94025 to provide a service contract for a PACBIO RSII SEQUENCER SYSTEM (BRAND NAME: PACIFIC BIOSCIENCES). Background: The National Institute of Health (NIH) mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The National Human Genome Research Institute (NHGRI) mission has expanded to encompass a broad range of studies aimed at understanding the structure and function of the human genome and its role in health and disease. NHGRI supports the development of resources and technology that will accelerate genome research and its application to human health. The National Human Genome Research Institute NHGRI), NIH Intramural Sequencing Center (NISC) is a high-throughput sequencing center supporting all institutes within the NIH. NISC has served the NIH community for over 15 years and established in 1997, as a source for high-quality large-scale sequencing and analysis. NISCH is a multi-disciplinary genomics facility that emphasizes the generation and analysis of DNA sequence. In addition to providing investigators at the NIH access to large-scale DNA sequencing, NISC plays a major role in several efforts related to the Human Genome Project including a Comparative Vertebrate Sequencing Initiative, the ENCODE Project, and the Mammalian Gene Collection Program. NISC is also an active participant in the International Sequencing Consortium. Purpose and Objectives: The purpose of this sole source solicitation is to procure a service contract for NHGRI/NISC for a Pacific Biosciences Pac Bio RS II Sequencer System. Pacific Biosciences Pac Bio RS II Systems is a Single Molecule, Real-Time (SMRT®) DNA Sequencing System that provides the highest consensus accuracy and longest read lengths of any available sequencing technology. NHGRI/NISC has a PacBio RS II, which is used to produce sequence reads in excess of 30 kb, but more typically 8-10kb. The length of the reads plus the lack of significant sequence bias in this method leads to full coverage of the genome, whereas other methods consistently leave gaps. This coverage enables determination of structural variation and repeat content as well as copy number data, all of which are difficult to discern from short read sequence data. In addition, RNA samples can be sequenced to discover the full spectrum of isoforms for genes of interest, and information about base modifications can be determined since this instrument is capable of sequencing directly from native DNA without amplification. The PacBio RS II instrument is critical for these types of studies, and is thus a vital component of NISC sequencing production pipeline. It is imperative that the PacBio RS II System is well maintained and operational so that NISC's work can be completed in a timely fashion and will not result in any disruption. Procurement: 1. Standard PacBio RSII System Service Contract, Part Number: 100-236-400, Serial Number: RS42231, Quantity: One (1) Each. Period of Performance:12-Months (June 2015 to June 2016) Other Important Considerations: Pacific Biosciences is the sole manufacturer of the PacBio RS II sequencer. The parts are unique to this instrument and cannot be substituted by other vendor parts. The engineers from Pacific Biosciences have the in-depth knowledge and training to repair this instrument. Pacific Biosciences will only allow Pacific Biosciences authorized and certified Engineers and Technicians for repairs, no other source. Contractor's Requirement: • The Contractor shall provide one on-site Preventative Maintenance visit per year.• The Contractor shall provide unlimited on-site emergency visits and up to four applications support visits per year.• The Contractor shall provide Parts and labor coverage for all routine service and maintenance visits.• The Contractor shall provide a Typical response time: 1 business day (remote), 3 business days (on-site).• The Contractor shall provide unlimited phone and email technical support [5am - 5pm Pacific Time, Monday - Friday].Government Responsibilities: • The Government will follow the operation procedures published by the Contractor, including procedures for routine maintenance. • The Government will maintain the Instrument site in accordance with the Contractor's environmental and electrical site specifications.• The Government will maintain a software release level within one major release of the most current O/S Software release made available by the Contractor. • The Government will not allow repairs, alterations, disassembly, reassembly or removal from facility by persons other than the Contractor or its certified designee.• The Government will adhere that the agreement does not cover service call fees incurred in investigating or remedying any damage or malfunction that results from improper or abnormal use, abuse, neglect, negligence, accident, externally caused short circuits, incorrect voltages, failure or fluctuation of electrical power, lightning, static or other improper external inputs, or Force Majeure.Reporting Requirements and Deliverables: • The Contractor shall provide a summary report of their action after a repair and/or preventive maintenance inspection.Inspection and Acceptance Requirements• The Government will accept the job performed by the Contractor. If it is a repair, equipment needs to demonstrate continuous performance.Regulatory Authority: The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2005-87-2, April 6, 2016. This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13 Simplified Acquisition Procedures (SAP) at the amount not exceeding the Simplified Acquisition Threshold (SAT) under $150,000.00. Statutory Authority: This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1(b)(1), Soliciting from a single source is not expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13--Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6-Competition Requirements. Additional Information: The acquisition is being conducted under FAR Part 13, simplified acquisition procedures, therefore the requirements of FAR Part 6 B Competitive Requirements are not applicable (FAR Part 6.001). Industry Classification (NAICS) Code is 811219, Other Electronic and Precision Equipment Repair and Maintenance and the Small Business Size Standard is $20.5M. Closing Statement: This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by April 18, 2016 and must reference synopsis number HHS-NIH-NHLBI-CSB-(HG)-2016-114-DM, may be submitted to the National, Heart, Lung and Blood Institute, Office of Acquisition, COAC Services Branch, 6701 Rockledge Drive, Suite 6149, Bethesda, Maryland 20892-7902, Attention: Dorothy Maxwell, Contracting Officer. Response may be submitted electronically to maxwelld@nhlbi.nih.gov. Faxes will not be accepted. Responses will only be accepted if dated and signed by an authorized company representative. "All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency."  

Illumina Service Contract

Department of Health and Human Services, National Institutes of Health | Published June 7, 2016  -  Deadline June 14, 2016
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THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR A PROPOSAL. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. INTRODUCTION: The National Heart, Lung, and Blood Institute (NHLBI) Office of Acquisition (OA) on behalf of the National Human Genome Research Institute, (NHGRI), intends to negotiate and award a purchase order on a non-competitive sole source basis to Illumina Inc., 9885 Towne Centre Drive, San Diego, California 92121-1975. BRAND NAME: ILLUMINA, INC. PROCUREMENT: Base Year: 12 Months;Option Year 1: 12 Months 1. Product Care Autoloader2, Basic Plan, Catalog Number: SV-202-1002, Serial Number: 11139-756, Units: One (1) Each;2. Product Care iScan, Basic Plan, Catalog Number: SV-102-1002, Serial Number: N345, Units: One (1) Each;3. Product Care iScan, Basic Plan, Catalog Number: SV-102-1002, Serial Number: N0278, Units: One Each; and4. PROD Care LiHa 1 PREVative MAIN Plan, Catalog Number: SV-121-2001, Serial Number: 708005550, Units: One Each. BACKGROUND: The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency conducting and supporting medical discoveries that improve people's health and save lives. The National Human Genome Research Institute (NHGRI), Genomic Technology Branch (GTB) studies the structure and function of genomes in disease and normal states. The investigators have developed world-class expertise in a wide range of genomic techniques, including the mapping and sequencing of mammalian chromosomes, gene isolation, systematic mutagenesis, developmental genomics, and computational analysis of DNA and protein sequences. GTB investigators are actively studying the genetic causes of rare disorders, such as hereditary deafness, progeria, and peripheral neuropathies. Also, the study of genetic contributions to more common conditions, such as type 2 diabetes and neural tube defects, and are investigating how particular genes may influence normal health and even longevity. PURPOSE AND OBJECTIVES: The Illumina The iScan (2), Autoloader and Tecan LiHa service contract is needed for the four instruments that are used every day in the Genomics Core lab. The Genomics Core makes genotyping services available to NHGRI investigator. The iScan (2), Autoloader and Tecan LiHa instruments have generated more than 2 billion SNP genotypes for investigators in six different branches in NHGRI institute in the last year. NGHRI investigators rely on the Genomics Core Lab to maintain the equipment to the highest standard, including having access to expert repairs, appropriate parts and technical support when the need should arise. The instruments procured from Illumina and have proprietary software and patent rights, which cannot be serviced by any other company. Only Illumina can provide service to these equipment and no other vendors are authorized to service these instruments. Illumina designed built, and optimized these instruments for efficient service. Illumina provided proprietary software for these instruments that allows the engineer to diagnose the defect and correct it. These were designed and build to meet the needs of the high-density arrays, and Illumina (and no one else) knows how to make these instruments work for these arrays. A. Contractor Requirements: 1. The Contractor shall provide service and maintenance of the Instrument, and support for the Software, for a period as defined on this Agreement. Includes full coverage on parts and labor.2. The Contractor shall provide On-Site response within three business days.3. The Contractor shall be available for Critical and non-critical updates which may be required in order to improve its use and reliability. Such updates shall be covered by this Agreement. Updated Software shall be subject to this Agreement in all respects. Updates shall not extend the defined Agreement coverage period.4. The Contractor shall provide full coverage of labor and necessary warranted parts.B. Government Responsibilities:1. The Government will keep the Equipment at all times in the environmental conditions recommended by the manufacturer. And, protect the Instrument and associated Hardware from all adverse elements, such as dirt, dust and liquids of any kind.2. The Government will use the Equipment only in accordance with such instructions and recommendations relating to the care and operation of the Equipment as may be issued by the manufacturer of the Equipment or as may from time to time be advised in writing by the Contractor.3. The Government will not allow any person other than the Contractor's representatives or the Customer's representative working under the Contractor's specific instruction, to maintain, repair or replace any part of the Equipment.4. The Government will understand that the Agreement does not cover repairs or software support required to remedy breakdown or damage which results from operator errors, abnormal or unapproved uses, unauthorized installed software or software updates, acts of third parties, viruses, faulty electrical connections, fluctuations or failures in air conditioning, heating or cooling systems and electrical power failures.5. The Government will adhere to normal daily, weekly, monthly, quarterly and semi-annual maintenance services such as the replacement of fuses, lamps, tubes, reagents and probes, as defined in the Operator Manual or Customer Bulletins.C. Reporting Requirements and Deliverables: • The Contractor shall provide a summary report of their action after a repair and/or preventive maintenance inspection.D. Inspection and Acceptance Requirements:• The Government will accept the job performed by the Contractor. If it is a repair, equipment needs to demonstrate continuous performance.E. Anticipated Period of Performance: Base Year: Twelve (12) months Option Year 1: Twelve (12) months F. Other Considerations: Illumina has exclusive rights, US Patent # US 7,589,315 and foreign equivalents for the HiSeq, MiSeq and cBot Clusters including trade secret and other proprietary rights. Regulatory Authority: This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13.106-1(b) Soliciting from a single source and is not expected to exceed the simplified acquisition threshold, only one responsible source and no other supplies or services will satisfy agency requirements. This requirement base and option 1 year period is under the SAT of $150,000.00. Statutory Authority: This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Contracts awarded using FAR Part 13-Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6-Competition Requirements. Additional Information: Industry Classification (NAICS) Code is 811219, Other Electronic and Precision Equipment Repair and Maintenance and the Small Business Size Standard is $20.5M. The acquisition is being conducted under FAR Part 13, simplified acquisition procedures, therefore the requirements of FAR Part 6 B Competitive Requirements are not applicable (FAR Part 6.001). The resultant Contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2005-88 (May 16, 2016). This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by June 14, 2016 and must reference synopsis number HHS-NIH-NHLBI-CSB-(HG)-2016-159-DM, may be submitted to the National, Heart, Lung and Blood Institute, Office of Acquisition, COAC Services Branch, 6701 Rockledge Drive, Suite 6149, Bethesda, Maryland 20892-7902, Attention: Dorothy Maxwell. Response may be submitted electronically to maxwelld@mail.nih.gov. Faxes will not be accepted. Responses will only be accepted if dated and signed by an authorized company representative. "All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency."

AU-FDS Electronics and Control System

Department of Health and Human Services, National Institutes of Health | Published May 12, 2016  -  Deadline May 23, 2016
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INTRODUCTION THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION. The National Heart, Lung, and Blood Institute (NHLBI), Office of Acquisitions (OA), intends to negotiate and award a purchase order on a noncompetitive sole source basis to Aviv Medical Inc, 750 Vassar Ave, Lakewood, NJ 08701, to procure an AU-FDS Electronics and Control System for NIBIB's Dynamics of Macromolecular Assembly Section. BACKGROUND The goal of the Dynamics of Macromolecular Assembly section (DMA), as part of the Laboratory of Cellular Imaging and Macromolecular Biophysics (LCIMB), is the development of biophysical tools for the characterization of reversible macromolecular interactions in biological systems. A significant part of the lab's work is focused on the development and application of methods to characterize thermodynamic and dynamic properties of chemical and biological molecules by analytical ultracentrifugation. This includes research on cutting edge detection approaches such as fluorescence detection for analytical ultracentrifugation. To this end, the lab has previously purchased two AU-FDS optics boxes with different wavelengths, which can be mounted into a dedicated analytical ultracentrifuge equipped with the accessory hardware and software to operate the AU-FDS optics box. Previously, the lab has embarked on the use of different excitation wavelengths in the fluorescence detection, and for this purpose has previously purchased a second AU-FDS optics box with a 561 nm excitation in addition to the system with 488 nm excitation that the lab already owns. Now the lab has the choice of either carrying out experiments with 488 nm excitation, or with 561 nm excitation. The lab has verified that both excitation wavelengths are very useful, and that the systems operate very well. Therefore, the lab is requesting the purchase of a second AU-FDS Electronics and Control System, so that they can run both optics boxes at the same time in different centrifuges. PURPOSE The purpose of this acquisition is to procure an AU-FDS Electronics and Control System for NIBIB's Dynamics of Macromolecular Assembly Section. This system is required by NIBIB to modify an existing analytical ultracentrifuge so that it can accept an existing AU-FDS optics box. PROCUREMENT The contractor shall provide the following: • Vacuum Manifold that provides hermetically sealed electrical connections into the AUC vacuum chamber.• System Box that includes cables and RS232 Switch Box that provides power for the AU-FDS, processes signals, and serves as an interface between the computer and distribution box.• Distribution Box that includes cables and interfaces the Systems Box, AUC signals and vacuum manifold.• Computer System that includes Windows 7 computer, high speed A/D boards, low speed A/D boards and advanced Operating System Software• Installation• Travel Expenses JUSTIFICATION Based on our market research we have determined that Aviv Biomedical is the sole manufacturer of the hardware and software that is compatible with NIBIB's existing AU-FDS optics boxes. Therefore, they are the only supplier that can fulfill the laboratory's specific requirements for this procurement. REGULATORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13.106-1(b) Soliciting from a single source (for purchases not exceeding the simplified acquisition threshold) and only one responsible source and no other supplies or services will satisfy agency requirements. ADDITIONAL INFORMATION Industry Classification (NAICS) Code is 334516, All Other Animal Production, and the Small Business Size Standard is 1000 employees. The acquisition is being conducted under FAR Part 13, Simplified Acquisition Procedures, therefore the requirements of FAR Part 6, Competitive Requirements, are not applicable (FAR Part 6.001). The resultant award will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 05-87 (April 6, 2016). This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by May 23, 2016 at 9:00AM EST and must reference synopsis number NHLBI-CSB-(HL)-2016-132-KMA. Responses shall be submitted to the National Heart, Lung, and Blood Institute, Office of Acquisitions, COAC Services Branch, 6701 Rockledge Drive, Room 6127, Bethesda, Maryland 20892-7902, Attention: Kevin Alvarez. Responses may be submitted electronically to kevin.alvarez@nih.gov. Faxes will not be accepted. Responses will only be accepted if dated and signed by an authorized company representative. "All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency."