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IN-SITU SITE REMEDIAL SERVICES

National Capital Commission | Published March 9, 2017  -  Deadline April 19, 2017
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Invitation

The National Capital Commission (NCC) is calling for Technical & Financial Proposal(s) from remediation contractors to provide in-situ site remediation services at two independent contaminated sites within the National Capital Commission’s Greenbelt in Ottawa, Ontario. Work under this Contract includes:

  1. In-Situ Activated Carbon Adsorption with Enhanced Bioremediation and/or Chemical Reduction to remediate soil and groundwater impacted with Volatile Organic Compounds at NCC Parking Lot P19 located on Leitrim Road, west of Ramsayville Road in Ottawa, ON (P19 Leitrim Road); and,

  2. In-Situ Activated Carbon Adsorption with Enhanced Bioremediation and/or Chemical Reduction to remediate soil and groundwater impacted with Petroleum Parameters (BTEX and F1-F4 Petroleum Hydrocarbons) at 16 Tauvette Street, Ottawa, ON. The in-situ remedial program at 16 Tauvette Street may be combined with source removal by excavation, if desired.

Please note that one Contract (for the two sites) or two Contracts (one per site), may be awarded as a result of this Request for Proposal. Basis of Award will be based on the lowest compliant offer per site

A non-mandatory site visit for 16 Tauvette has been scheduled for Wednesday, March 29th, 2017 at 10am, EDT. Bidders can enter the site from 2389 Pépin Court. https://goo.gl/maps/GJZoNYimVaP2 . If there is still a lot of snow, bidders will have to park beside the red barn and walk to the remedial area. If clear, the bidders may proceed to the parking lot at the rear of the property. https://goo.gl/maps/SgXvrirKfUB2 Please drive slowly (max 10 km/h) on the property. NCC representative(s) will meet bidders near the barn or rear parking lot. Bidders are invited to visit P19 Leitrim https://goo.gl/maps/MTKHoBePQDE2 at their discretion since the site is accessible to the public. Note: Google links above require Google Chrome web browser

The official Government Electronic Tendering Service website is http://buyandsell.gc.ca . Please ensure that you download your document from this site, in order to obtain all information related to the tender. It is your responsibility to ensure that you have received all the posted tender information to ensure tender compliance and not be disqualified.
Tenders & bid security must be forwarded to the attention

Procurement Services, National Capital Commission

40 Elgin Street, 2nd Floor Security Office

Ottawa, ON K1P 1C7

Envelope to reference NCC tender file # AL1696.

Bid closing date is April 19, 2017 at 3pm EDT. Late or faxed bids will not be accepted.
There is no public opening scheduled.
The procurement process of this tender is subject to WTO - Agreement on Government Procurement.

CBRN Moulded Protective Gloves with Liner

Royal Canadian Mounted Police | Published December 16, 2015
Winner
Airboss Defense
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Requirement: CBRN Moulded Butyl Rubber Gloves with Liner in various sizes The RCMP, Chemical Biological Radiological Nuclear (CBRN) First Responder Program (FRP) has a requirement for a firm quantity of 612 pairs CBRN Moulded Butyl rubber gloves, complete with liner in various sizes. The proposed procurement includes an option to purchase an additional maximum quantity of 5,000 pairs CBRN Moulded Butyl rubber gloves complete with liner on an ‘'as and when'’ requested basis during a 5 year period from date of contract award. The firm quantity of 612 is requested to be delivered sixty (60) calendar days from the effective date of contract award. GSIN: N8415 Applicable Trade Agreements: AIT This requirement is limited to authorized Airboss Defense Canadian distributors and or resellers. The RCMP will not accept any substitute product for this requirement. The Responsive Bid with the lowest evaluated price will be recommended for award of a contract. There will only be one contract awarded as a result of this solicitation. Delivery to be made to The Royal Canadian Mounted Police in Ottawa, Ontario. The Bidder must ensure that the required pre-award sample is manufactured in accordance with the technical requirement and is fully representative of the bid submitted. Rejection of the pre-award sample will result in the bid being declared non-responsive. The Crown reserves the right to negotiate with suppliers on any procurement. Documents may be submitted in either official language of Canada. For more information on The RCMP National Procurement Plan for fiscal year 2014-2015 please visit http://www.rcmp-grc.gc.ca/pubs/cm-gg/index-eng.htm

CBRN Moulded Protective Gloves with Liner

Royal Canadian Mounted Police | Published December 31, 2014  -  Deadline December 1, 2015
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Requirement: CBRN Moulded Butyl Rubber Gloves with Liner in various sizes The RCMP, Chemical Biological Radiological Nuclear (CBRN) First Responder Program (FRP) has a requirement for a firm quantity of 612 pairs CBRN Moulded Butyl rubber gloves, complete with liner in various sizes. The proposed procurement includes an option to purchase an additional maximum quantity of 5,000 pairs CBRN Moulded Butyl rubber gloves complete with liner on an ‘'as and when'’ requested basis during a 5 year period from date of contract award. The firm quantity of 612 is requested to be delivered sixty (60) calendar days from the effective date of contract award. GSIN: N8415 Applicable Trade Agreements: AIT This requirement is limited to authorized Airboss Defense Canadian distributors and or resellers. The RCMP will not accept any substitute product for this requirement. The Responsive Bid with the lowest evaluated price will be recommended for award of a contract. There will only be one contract awarded as a result of this solicitation. Delivery to be made to The Royal Canadian Mounted Police in Ottawa, Ontario. The Bidder must ensure that the required pre-award sample is manufactured in accordance with the technical requirement and is fully representative of the bid submitted. Rejection of the pre-award sample will result in the bid being declared non-responsive. The Crown reserves the right to negotiate with suppliers on any procurement. Documents may be submitted in either official language of Canada. For more information on The RCMP National Procurement Plan for fiscal year 2014-2015 please visit http://www.rcmp-grc.gc.ca/pubs/cm-gg/index-eng.htm

CBRN Moulded Butyl Rubber Gloves

Royal Canadian Mounted Police | Published November 12, 2014
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Requirement: CBRN Moulded Butyl Rubber Gloves with Liner in various sizes The RCMP, Chemical Biological Radiological Nuclear (CBRN) First Responder Program (FRP) has a requirement for a firm quantity of 612 pairs CBRN Moulded Butyl rubber gloves, complete with liner in various sizes. The proposed procurement includes an option to purchase an additional maximum quantity of 5,000 pairs CBRN Moulded Butyl rubber gloves complete with liner on an ‘'as and when'’ requested basis during a 5 year period from date of contract award. The firm quantity of 612 is requested to be delivered sixty (60) calendar days from the effective date of contract award. GSIN: N8415 Applicable Trade Agreements: AIT This requirement is limited to authorized Airboss Defense Canadian distributors and or resellers. The RCMP will not accept any substitute product for this requirement. The Responsive Bid with the lowest evaluated price will be recommended for award of a contract. There will only be one contract awarded as a result of this solicitation. Delivery to be made to The Royal Canadian Mounted Police in Ottawa, Ontario. The Bidder must ensure that the required pre-award sample is manufactured in accordance with the technical requirement and is fully representative of the bid submitted. Rejection of the pre-award sample will result in the bid being declared non-responsive. The Crown reserves the right to negotiate with suppliers on any procurement. Documents may be submitted in either official language of Canada. For more information on The RCMP National Procurement Plan for fiscal year 2014-2015 please visit http://www.rcmp-grc.gc.ca/pubs/cm-gg/index-eng.htm

Support for Implementation, Adaptation and Improvement of the CFIA's Establishment-Based Risk Assessment Model

Canadian Food Inspection Agency | Published April 13, 2017  -  Deadline May 23, 2017
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The CFIA is modernizing its inspection system and developing a risk-based model for assigning inspection resources to the food establishments under its jurisdiction within Canada and for countries exporting to Canada.

When such a model is put into practice, close monitoring is needed to check the model’s performance, identify and correct shortcomings and make the necessary changes.

The CFIA has therefore agreed to have the model periodically updated so that the data used as its input are the latest and most pertinent, thus preserving its scientific value.

The ERA model will be applied not only in Canadian food production facilities, but also in establishments that export to Canada. An initial evaluation of the steps needed to incorporate imports into the model has already been made. It quickly became apparent that significant changes with regard to certain risk factors would be necessary as serious limitations emerged as to the sources of data to feed the model. Adapting the ERA model to cover imports will thus be more complex than expected and will be the subject of work under this contract.

Similarly, CFIA’s Science Branch has decided to develop a model on ERA lines, or an adaptation of it, for hatcheries under CFIA jurisdiction in Canada.

Lastly, when the model’s performance is evaluated and updated, including inclusion of chemical hazards at every step in the mitigation measures and facility history, plans provide for in-depth reviews of the literature and applied research projects, targeting, for example, levels of pathogenic bacteria in certain foodstuffs.

Electron Probe X-Ray Micro Analyzer

Natural Resources Canada | Published October 6, 2017  -  Deadline November 15, 2017
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Trade Agreement: CETA / WTO-AGP / NAFTA / CFTA / FTAs with Peru / Colombia / Panama / Korea Tendering Procedures: All interested suppliers may submit a bid Competitive Procurement Strategy: Lowest/Lower Bid Comprehensive Land Claim Agreement: No Nature of Requirements:   The research facilities at the Lands and Minerals Sector (CanmetMINING, Geological Survey of Canada) has a requirement for an Electron Probe X-ray Micro Analyzer (EPMA) System to image and obtain highly precise chemical analyses of phase at high spatial resolution down to the micrometer scale.  The complexity of natural earth materials that need EPMA characterization in the context of the research performed at the Lands and Minerals Sector require the ability to perform sophisticated correction of matrix effects as well as state-of-the-art modeling of background, spectral interferences, peak shape alterations, migrating elements (e.g. alkalis), and surface segregation, in order to obtain accurate analyses and quantitative X-ray maps with a traceable approach. To achieve this requirement, the EPMA must also be equipped with one additional recognized automation/quantification/imaging system (e.g. Probe for EPMA/Probe Image; Probe Software Inc.) that is fully compatible with the hardware of the EPMA.  This additional quantification and imaging system must include all of the following:   a) all hardwares, licenses, interface and communication protocols, accompanying graphing and mapping softwares, as well as the full installation.   Delivery:  On or before March 30th, 2018 to Ottawa, Ontario  Installation and basic Training: Must be completed two months after the delivery date of the EPMA system and on-site training must be provide at the time of installation.  Extended Warranty including Maintenance and Support Services for 4 optional one-year periods     Delivery Date: Above-mentioned  The Crown retains the right to negotiate with suppliers on any procurement.  Documents may be submitted in either official language of Canada.

Various Training Courses for the Occupational Health and Safety (OHS) Unit of Natural Resources Canada (NRCan)

Natural Resources Canada | Published December 7, 2016  -  Deadline January 23, 2017
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By means of this Request for Standing Offer (RFSO), The Occupational Health and Safety (OHS) Branch of Natural Resources Canada (NRCan) is seeking proposals from Offerors to provide various training sessions, on an “as and when required” basis. The following are the Workstreams to be provided, along with a list of individual training courses to be provided under each Workstream. The majority of these training courses will be in the National Capital Region (NCR); however there could be a need for our Regional Offices to request this training. Regional offices consist of: British Columbia (Sidney and Vancouver), Alberta (Calgary and Edmonton), Quebec (Quebec City) and Nova Scotia (Halifax and Dartmouth).

Workstream 1 – Outdoor Vehicle/Equipment Training:

WS1.1 All-Terrain Vehicle (ATV) training

WS1.2 Boating Operation Practical Training

WS1.3 Chainsaw Operation Training

WS1.4 Snowmobile Operator Training

WS1.5 Forklift Operator Training

WS1.6 Small Engine Mechanics Training

WS1.7 Front Loader Training

WS1.8 Scissor Lift Training

WS1.9 Working at Heights Training

WS1.10 Mobile Crane Training

WS1.11 Respirator Fit Testing

WS1.12 Confined Space Training

Workstream 2 – Wildlife Awareness Training:

WS2.1 Black Bear Awareness Training

WS2.2 First Aid Wilderness Training

WS2.3 Predator Defense Training

Workstream 3 – Dangerous Goods Training:

WS3.1 Transportation of Dangerous Goods (TDG) Training

WS3.2 Chemical and Gas Handling Training

WS3.3 Fire Extinguisher Hands-on Training

WS3.4 Canadian Firearms Safety Course

Workstream 4 – Miscellaneous Training:

WS4.1 Back Care Ergonomics Combo Training

WS4.2 Helicopter Safety Awareness Training

WS4.3 Psychological Health and Safety Standard Training

Note: Bidders can provide training on all courses or a portion of the courses to be considered for a Standing Offer Agreement. Bidders need to clearly identify in their proposal which Workstreams and courses under that Workstream you will be bidding on as well as which Regions.

Business analyst

Health Canada | Published October 27, 2014
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TASK Based Professional Services (TSPS) Requirement This requirement is for: Health Canada This requirement is open only to those Supply Arrangement Holders under E60ZN-13TSPS/ who qualified under Tier “ 1 ” (= $0-$2M ) stream two for Business Consulting / Change Manaagement This requirement is open only to those invited TSPS Supply Arrangement Holders who qualified under the stream for: Business Analyst The following SA Holders have been invited to submit a proposal. Accenture Inc. Access Corporate Technologies Inc. Chazey Partners Canada Inc. Eclipsys Solutions Epixus Inc. Excelsa Technologies Consulting Inc. Fujitsu Consulting (Canada) Inc. NATTIQ MHPM Project Managers Inc. OLAV Consulting Corp., MOSHWA Aboriginal Information Technology Corporation, in Joint Venture OpenFrame Technologies, Inc. S.i. Systems Ltd Sierra Systems Group Inc. The Strategic Review Group Inc. Transpolar Technology Corporation and The Halifax Computer Consulting Group in Joint Venture Description of the requirement: Health Canada has a requirement for a Business Analyst to do a feasibility assessment of developing a Canadian surveillance system for poisonings, chemical intoxications and adverse drug reactions, using data generated by five Canadian Regional Poison Control Centres. At the completion of the contract a business case, developed in accordance with Treasury Board guidelines, will be delivered to the Health Portfolio Task Force on a Canadian Surveillance System for Poison Information. The business case will be used to inform senior management decision making on the potential development of a Canadian Surveillance System for Poison Information (CSSPI). Security Requirement: The successful supplier will have a Designated Organizational Screening (DOS) as granted by the Canadian Industrial Security Directorate (CISD) and the resource(s) assigned to perform the work will have a Reliability status as granted by CISD. There is no Document Safeguarding Capability (DSC) required for this work. Proposed period of contract: The proposed period of contract shall be from November 17, 2014 to April 17, 2015. File Number: 1000163953a Contracting Authority: Robert Merrick Phone Number: 613-946-3159 E-Mail: Richard.Wootton @hc-sc.gc.ca Robert.Merrick@hc-sc.gc.ca NOTE: The Task and Solutions Professional Services (TSPS) Method of Supply is subject to quarterly refresh cycles. If you wish to find out how you can be a “Qualified SA Holder”, please contact SPTS.TSPS@TPSGC-PWGSC.GC.CA

JOINT CBRN GEN. SVC RESPIRATOR-VP

Department of National Defence | Published April 15, 2016  -  Deadline April 22, 2016
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Trade Agreement: NONE Tendering Procedures: All interested suppliers may submit a bid Competitive Procurement Strategy:  Comprehensive Land Claim Agreement: No Nature of Requirements:   JOINT CBRN GEN. SVC RESPIRATOR-VP  W8476-155142/A SUBJECT: Letter of Interest Joint Chemical Biological Radiological Nuclear General Service Respirator  (Joint CBRN GSR) Project  1. Introduction 1.1 The Canadian Armed Forces (CAF) has a requirement for a Chemical, Biological, Radiological and Nuclear (CBRN) respirator to replace the current in-service respirator. 1.2  The Department of National Defence (DND) intends to procure Commercial Off-The-Shelf (COTS), Military Off-The-Shelf (MOTS) or modified COTS/MOTS respirator systems through a competitive procurement process to meet the CAFs need. 1.3  It is anticipated that 62,000 Joint CBRN GSR systems will be required with an option for a further 15,800. Each Joint CBRN GSR system will consist of the respirator (including its filter system), and any respirator accessories required per original equipment manufacturers (OEM) design necessary to meet the requirements of the System Requirements Specification (SRS) and any required test equipmentadapters.   1.4 This requirement is subject to the Industrial and Technological Benefits (ITB) including Value Proposition (VP) policy.   2. Purpose 2.1 The purpose of this Letter of Interest (LOI) is to:  a. Seek industry feedback on: i. The draft ITB including VP documentation;  ii. The proposed VP evaluation framework, pillar weightings; and any changes you would make; iii. The proposed CBRN market segment definitions; and any changes you would make and; iv. Given that the current proposalis 15% VP, 65% Technical/Management and 20% Cost what is your view on an appropriate VP% and why?  b. Allow industry to discuss and ask questions on the ITB including VP portion of the project by participating in a one-on-one teleconference with Innovation, Science and Economic Development Canada.  Please fill out the Innovation, Science and Economic Development Canada One-on-One Consultation form to indicate your preferred date, time and attendance.  3.  Invitation to respondents 3.1 Interested respondents are invited to request an electronic copy of the draft VP documents from the Contracting Authority at the e-mail address indicated below. 3.2 Respondents are invited to submit their response to the LOI by e-mail to the Contracting Authority on or before April 22nd, 2016.  4.  Additional Information to respondents 4.1  No payment will be made for costs incurred in the preparation and submission of a response to the LOI. Costs associated with preparing and submitting a response, as well as any costs incurred by the respondent associated with the evaluation of the LOI, are the sole responsibility of the respondent. 5.  Request For Response  5.1  Formal responses to this LOI and all inquiries during the LOI posting period must be directed to the Contracting Authority. 5.2  Contracting Authority:  Martin Lalonde  Supply Team Leader  Scientific, Medical and Photographic Equipment Division  Public Works and Government Services Canada  E-mail: martin.lalonde@tpsgc-pwgsc.gc.ca  6.  No Obligation 6.1 Canada will not be bound by anything stated in this LOI or any other document provided with the LOI or documents provided by Canada further to a respondents request. Canada reserves the right to change, at any time, all or part of theproject requirements as it considers necessary, as the project progresses.  6.2 The issuance of this LOI does not create an obligation for Canada to issue a subsequent bid solicitation and does not bind Canada legally or otherwise, to enter into any agreement or to accept any suggestions from industry. 6.3 This LOI and subsequent Industry Consultation are not a bid solicitation and no contract will result from this request. 6.4 There will be no short listing of firms for purposes of undertaking any future work, as a result of this LOI. Similarly, participation in this LOI is not a condition or prerequisite for participation in any RFP. 6.5  Companies participating in this LOI should identify any submitted information that is to be considered as either company confidential or proprietary.   Delivery Date: Above-mentioned  The Crown retains the right to negotiate with suppliers on any procurement.  Documents may be submitted in either official language of Canada.

R613.4 Laboratory determination of sealing material performance

Canadian Nuclear Safety Commission | Published November 3, 2014
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Annex A – Statement of Work 1. Objective The objective of this research is to obtain laboratory data on the performance of bentonite seal materials in a brine environment. The data are will be used in the development of numerical models by the CNSC to assess the long-term performance of sealing materials for repositories in sedimentary rock. 2. Background Two initiatives for the deep geological disposal of radioactive wastes are currently being proposed for Canada, and are being evaluated and investigated by the CNSC. The proposed repositories rely on both the surrounding host rock and engineered barriers to contain and isolate waste from the biosphere for hundreds of thousands to millions of years. The success of both projects depends largely on the long term performance of these barriers. CNSC has developed a Coordinated Assessment and Research Program on the safety of geological repositories (CARP). This program examines the long term performance of both the geological and engineered barriers. Over the long term, the host rock is a natural and major barrier to contaminant migration from repository waste. Therefore, the previous phase of CARP focused on geoscientific aspects of the host rock. However, preliminary long term safety assessments performed by the Nuclear Waste Management Organization (NWMO) have shown that bentonite seals used in the repository galleries and shafts also play an important role by minimizing preferential pathways for contaminant transport. Therefore, the current phase of the CARP is being extended to examine the long term performance of those engineered barriers. The CNSC collaborates with the IRSN (the Institut de Radioprotection et de Sûreté Nucléaire, France) in the SEALEX project, which involves a series of in-situ tests on the long term performance of sealing materials at the IRSN’s Tournemire underground research laboratory. The SEALEX project provides the CNSC with a wealth of experimental data that allows the CNSC to develop mathematical models for the long term performance of those sealing materials. One particular feature of Canadian sedimentary rocks is the existence of brine at anticipated repository depths of more than 500 m [1]. Experimental evidence shows that salinity plays an important role on the hydraulic, chemical and mechanical characteristics of bentonite seals. However, the experiments conducted so far were only performed at salinity concentrations much lower than the 200-300 g/l concentration levels of Canadian brines. For repositories proposed in Canadian sedimentary rocks, there is therefore a strong need to understand the interaction of the brine and the bentonite-based seals, in order to assess their long term performance as a barrier to water and gas flow. 3. References [1] NWMO, 2011. OPG’s Deep Geologic Repository for Low and Intermediate Level Waste: Geosynthesis. Report NWMO DGR-TR-2011-11 (http://www.nwmo.ca/dgrsubmission) [2] Barnichon J.D. and Deleruyelle F. Sealing experiments at the Tournemire URL: the SEALEX Project. Eurosafe 2009 [3] Barnichon J.D., Dick P. and Bauer C. (2011) The SEALEX in situ experiments: Performance tests of repository seals. In: Harmonising Rock Engineering and the Environment – Qian & Zhou (eds) © 2012 Taylor & Francis Group, London, ISBN 978-0- l415-80444-8, pp. 1391-1394 [4]DECOVALEX 2015- description of task A: http://www.decovalex.org/task-a.html [5]Wang, Q., Tang, A.M., Cui, Y., Delage, P., Barnichon, J.D., Ye, W.M (2013). The effects of technological voids on the hydro-mechanical behaviour of compacted bentonite-sand mixture. Soils and foundations 53, 2 (2013) 232-245 4. Scope of Work Perform laboratory tests to obtain hydro-mechanical characteristics and simulated long term evolution of a 70-30 bentonite-sand mixture, using brine as pore water. Laboratory testing will need to extend over a period of at least 2 years. 5. Tasks to be Performed 5.1 Design and produce a model water to represent porewater in the Cobourg limestone of the Michigan Basin, at depths of approximately 700 m. 5.2 Prepare MX-80 bentonite at a dry density of 1.61 and 1.41 Mg/m3. Prepare MX-80 bentonite/sand mixture similar to the ones used in the SEALEX project [2, 3] at dry densities of 1.65, 1.8 and 1.95 Mg/m3. 5.3 Perform oedometer and hydration tests on MX-80 and MX-80 bentonite/sand mixture with the model water to determine water retention, swelling pressure and other index properties (e.g. swell index). 5.4 Perform a parallel study of microstructure properties to observe changes over time. 5.5 Perform “mock-up” tests with a technological void similar to the one described in [4, 5]. The bentonite/sand mixture at an initial dry density of 1.95 Mg/m3 will be used in these tests. Instead of steel cells, the contractor should consider using hollow cylindrical samples of Cobourg Limestone as confining vessels. Perform gas/liquid injection test in one sample after the technological void has been filled and a steady-state swelling pressure is reached. 5.6 Perform chemical testing of pore waters over time and measure the cation exchange capacity after testing.

PARTS FOR STEAM GENERATOR

Department of National Defence | Published November 17, 2017  -  Deadline December 29, 2017
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NOTICE OF PROPOSED PROCUREMENT

The Department of National Defence has a requirement for the items detailed below. The delivery is requested at CFB Halifax and CFB Esquimalt.

Item 1, GSIN: 4530, NSN: 01-507-5249, NOZZLE,OIL BURNER,PRESSURE ATOMIZING

Acceptable Part No.: 18459, NCAGE: 12736

Quantity: 40, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 2, GSIN: 4530, NSN: 01-507-5249, NOZZLE,OIL BURNER,PRESSURE ATOMIZING

Acceptable Part No.: 18459, NCAGE: 12736

Quantity: 40, Unit of Issue: EA, to be delivered to CFB Halifax

Item 3, GSIN: 4140, NSN: 01-507-5351, FAN ASSEMBLY,CENTRIFUGAL

Acceptable Part No.: CM-4559, NCAGE: 12736

Quantity: 4, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 4, GSIN: 4140, NSN: 01-507-5351, FAN ASSEMBLY,CENTRIFUGAL

Acceptable Part No.: CM-4559, NCAGE: 12736

Quantity: 6, Unit of Issue: EA, to be delivered to CFB Halifax

Item 5, GSIN: 5640, NSN: 01-118-7178, CEMENT,INSULATION,HIGH TEMPERATURE

Acceptable Part No.: 11297, NCAGE: 12736

Quantity: 9, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 6, GSIN: 5640, NSN: 01-118-7178, CEMENT,INSULATION,HIGH TEMPERATURE

Acceptable Part No.: 11297, NCAGE: 12736

Quantity: 3, Unit of Issue: EA, to be delivered to CFB Halifax

Item 7, GSIN: 6685, NSN: 01-507-5251, GAGE,PRESSURE,DIAL INDICATING

Acceptable Part No.: 26586, NCAGE: 12736

Quantity: 26, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 8, GSIN: 6685, NSN: 01-507-5251, GAGE,PRESSURE,DIAL INDICATING

Acceptable Part No.: 26586, NCAGE: 12736

Quantity: 9, Unit of Issue: EA, to be delivered to CFB Halifax

Item 9, GSIN: 6685, NSN: 01-617-1387, THERMOCOUPLE ASSEMB

Acceptable Part No.: 31355, NCAGE: 12736

Quantity: 2, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 10, GSIN: 6685, NSN: 01-617-1387, THERMOCOUPLE ASSEMB

Acceptable Part No.: 31355, NCAGE: 12736

Quantity: 2, Unit of Issue: EA, to be delivered to CFB Halifax

Item 11, GSIN: 4330, NSN: 01-528-9821, BASE ASSEMBLY,BURNER

Acceptable Part No.: UH-30671, NCAGE: 12736

Quantity: 2, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 12, GSIN: 4330, NSN: 01-528-9821, BASE ASSEMBLY,BURNER

Acceptable Part No.: UH-30671, NCAGE: 12736

Quantity: 5, Unit of Issue: EA, to be delivered to CFB Halifax

Item 13, GSIN: 4530, NSN: 01-528-9820, PAN ASSEMBLY,REFRACTORY

Acceptable Part No.: UH-30093, NCAGE: 12736

Quantity: 1, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 14, GSIN: 4530, NSN: 01-528-9820, PAN ASSEMBLY,REFRACTORY

Acceptable Part No.: UH-30093, NCAGE: 12736

Quantity: 2, Unit of Issue: EA to be delivered to CFB Halifax

Item 15, GSIN: 4410, NSN: 01-520-5381, PUMP,CHEMICAL

Acceptable Part No.: 38172, NCAGE: 12736

Quantity: 2, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 16, GSIN: 4410, NSN: 01-520-5381, PUMP,CHEMICAL

Acceptable Part No.: 38172, NCAGE: 12736

Quantity: 5, Unit of Issue: EA, to be delivered to CFB Halifax

Item 17, GSIN: 6685, NSN: 01-298-6852, GAGE,PRESSURE,DIAL INDICATING

Acceptable Part No.: 27789, NCAGE: 12736

Quantity: 15, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 18, GSIN: 6685, NSN: 01-298-6852, GAGE,PRESSURE,DIAL INDICATING

Acceptable Part No.: 27789, NCAGE: 12736

Quantity: 15, Unit of Issue: EA, to be delivered to CFB Halifax

Item 19, GSIN: 6150, NSN: 00-490-7673, LEAD,ELECTRICAL

Acceptable Part No.: UH33200, NCAGE: 12736

Quantity: 8, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 20, GSIN: 6150, NSN: 00-490-7673, LEAD,ELECTRICAL

Acceptable Part No.: UH33200, NCAGE: 12736

Quantity: 23, Unit of Issue: EA, to be delivered to CFB Halifax

Item 21, GSIN: 4410, NSN: 20-A01-5649, HARDNESS TEST KIT

Acceptable Part No.: 59438, NCAGE: 12736

Quantity: 5, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 22, GSIN: 4410, NSN: 20-A01-5649, HARDNESS TEST KIT

Acceptable Part No.: 59438, NCAGE: 12736

Quantity: 7, Unit of Issue: EA, to be delivered to CFB Halifax

Item 23, GSIN: 4820, NSN: 01-507-5246, VALVE,SAFETY RELIEF

Acceptable Part No.: 31291, NCAGE: 12736

Quantity: 9, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 24, GSIN: 4820, NSN: 01-507-5246, VALVE,SAFETY RELIEF

Acceptable Part No.: 31291, NCAGE: 12736

Quantity: 8, Unit of Issue: EA to be delivered to CFB Halifax

Item 25, GSIN: 3030, NSN: 20-A0H-1437, BELT,V

Acceptable Part No.: 36112, NCAGE: 12736

Quantity: 3, Unit of Issue: EA, to be delivered to CFB Esquimalt

Item 26, GSIN: 3030, NSN: 20-A0H-1437, BELT,V

Acceptable Part No.: 36112, NCAGE: 12736

Quantity: 8, Unit of Issue: EA, to be delivered to CFB Halifax

Bidders proposing an Equivalent or a Substitute Product must indicate the brand name and model and/or Part Number and the NCAGE they are offering.

The Crown retains the rights to negotiate with suppliers on any procurement.

Documents may be submitted in either official language of Canada.

TSPS Technician - Intermediate Analytical Chemistry

Department of National Defence | Published March 16, 2015  -  Deadline March 31, 2015
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NOTICE OF PROPOSED PROCUREMENT This requirement is only open to the below list of pre-qualified suppliers under the Task and Solutions Professional Services (TSPS). TASK BASED E60ZN-13TSPS PROFESSIONAL SERVICES REQUIREMENT FILE NUMBER: DND 14/0030863 TIER 1 (< $2M) This requirement is for the Department of National Defence (DND). This requirement is for the Technical Engineering and Maintenance Services (TEMS) Class for the services of one (1) Technician, Level 2 and one (1) optional Technician, Level 2. Number of Contracts: One contract to be awarded. Request for Proposal (RFP) documents will be e-mailed directly, from the DND Point of Contact (DND POC), to the Qualified Supply Arrangement Holders who are being invited to bid on this requirement. BIDDERS ARE ADVISED THAT RFP DOCUMENTS ARE NOT AVAILABLE ON THE GOVERNMENT ELECTRONIC TENDERING SYSTEM (https://buyandsell.gc.ca/tenders). Location of Work to be Performed Region: National Capital Region (NCR) Specific Location: 45 Sacré-Cœur Boulevard, Gatineau, Quebec Security Requirement Security Requirements Check List: Common PS SRCL #20 Supplier Security Clearance required: Facility Security Clearance – Secret Security Level required (Document Safeguarding): None Enquiries: Enquiries regarding this RFP requirement must be submitted to the DND POC listed below. File Number: DND 14/0030863 DND POC: Amber Tower E-Mail: DSvcsC4Contracting-DCSvcs4Contrats@forces.gc.ca DND requires the services of one (1) Technician, Level 2 and one (1) optional Technician, Level 2 to support the activities of the Quality Engineering Test Establishment (QETE) Applied Science program. The resource(s) will provide qualitative and quantitative physical and chemical analytical services in support of failure/accident investigations, specialist test and evaluation as well as Materiel Acquisition and Support related tasks. This requirement will be from date of award to two (2) years later, with an irrevocable option for up to three (3) additional one-year option periods. Documents may be submitted in either official language of Canada. The TSPS Method of Supply is a result of a formal competitive process which was established as a result of extensive consultations with industry. The Method of Supply provides suppliers with an on-going opportunity to become pre-qualified for participation in future bidding opportunities. To obtain more information about how to become a pre-qualified supplier for TSPS, please contact Public Works and Government Services Canada (PWGSC) at: spts.tsps@tpsgc-pwgsc.gc.ca. For general information on the various PWGSC Methods of Supply, or to obtain specific information on a PWGSC professional service method of supply, please visit PWGSC's Buy and Sell website at: https://buyandsell.gc.ca/for-businesses/selling-to-the-government-of-canada/register-as-a-supplier/register-to-provide-services. List of Pre-Qualified Suppliers This requirement is open only to the following companies who qualified under the stated consultant categories, level of expertise, security level, region and tier: 1. ACF Associates Inc. 2. ADGA Group Consultants Inc. 3. Adirondack Information Management Inc., The AIM Group Inc. in Joint Venture 4. AEROTEK ULC 5. Altis Human Resources (Ottawa) Inc. 6. Amtek Engineering Services Ltd. 7. BMT Fleet Technology Limited 8. CAE Inc. 9. Calian Ltd. 10. Fleetway Inc. 11. GasTOPS Ltd. 12. International Safety Research Inc. 13. Michael Wager Consulting Inc. 14. Modis Canada Inc. 15. Noramtec Consultants Inc. 16. Orbis Risk Consulting Inc. 17. Platinum Technologies Inc. 18. Promaxis Systems Inc. 19. T.E.S. Contract Services Inc. 20. The AIM Group Inc. 21. Valcom Consulting Group Inc.

LC-MS/MS

Health Canada | Published December 22, 2015  -  Deadline June 1, 2016
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Trade Agreement: WTO-AGP/NAFTA/AIT/Canada FTAs with Peru/Colombia/Panama Tendering Procedures: Generally only one firm has been invited to bid Non-Competitive Procurement Strategy: Exclusive Rights Comprehensive Land Claim Agreement: No Vendor Name and Address: AB Sciex LP 71 Four Valley Dr Concord Ontario Canada L4K4V8 Nature of Requirements: 1. Advance Contract Award Notice (ACAN) An ACAN is a public notice indicating to the supplier community that a department or agency intends to award a contract for goods, services or construction to a pre-identified supplier, thereby allowing other suppliers to signal their interest in bidding, by submitting a statement of capabilities. If no supplier submits a statement of capabilities that meets the requirements set out in the ACAN, on or before the closing date stated in the ACAN, the contractingofficer may then proceed with the award to the pre-identified supplier. 2. Definition of the requirement Health Canada has a requirement for the supply and installation of 2 LC-MS/MS with user training for up to 3-4 persons for delivery to Ottawa, Ontario. The delivery is required by 31st March 2016. 3. Criteria for assessment of the Statement of Capabilities Any interested supplier must demonstrate by way of a statement of capabilities that its system meets the following requirements: The equipment is required to measure baseline levels of priority chemicals, including those mandated under the Government of Canada Chemicals Management Plan (CMP), and is essential for data collection in a timely manner to support regulatory activities. This equipment is necessary in order to collect ultra-low level exposure data in a wide variety of food matrices that is required for risk management decisions and setting compliance levels for these chemicals. The new system must be equipped with a Differential ion mobility separation (DMS) technology to distinguish isobaric metabolites and to remove isobaric matrix interferences resulting in a reduction in chemical background noise. The new system must be equipped with an off-axis curved LINAC collision cell to prevent neutral molecules entering the last quadrupole analyzer and the ion detection system, thus reduce the noise and lower the limit of detection. In order to analyze high molecular weight analytes (such as long-chain perfluorinated compounds), the new system must have a mass range of both quadrupole mass analyzers not less than 2,000 Da. The new system must have a scanning speed of both quadrupoles not slower than 12,000 Da/sec in all MS/MS scanning modes to obtain enough data points for the ever-narrower UPLC peaks. For multiple analyte analyses, the new system must have a minimum MRM cycle time (including the dwell time and inter-channel setting time) not slower than 5 msec. The responses under this rapid MRM transitionsmust not be different from long dwell time settings (e.g. 100 ms dwell and 10 msec inter-channel setting time). The new system must have a fast polarity switching (<5 msec) between positive ion detection and negative to be able simultaneously collect information on hundreds different contaminants with polar functional. the new system must have an additional dimension (3rd dimension) of ms mrm3 analyses for unambiguous confirmation in both quantitative qualitative determination trace when high chemical background or challenging co-eluting interferences present in complex food matrices. Due to the complexity of the samples investigated and the narrow UPLC peaks, the new system must have a scanning speed in trapping mode to be at least 15,000 Da/sec to obtain enough data points. 4. Applicability of the trade agreements to the procurement This procurement is subject to the following trade agreements: Agreement on Internal Trade (AIT) World Trade Organization - Agreement on Government Procurement (WTO-AGP) North American Free Trade Agreement (NAFTA) 5. Justification for the Pre-Identified Supplier The only known supplier of a LC-MS/MS meeting all the above required technical specifications is the QTRAP® 6500+ from AB Sciex. For this reason, it is proposed to negotiate this requirement with the manufacturer AB Sciex, Concord, Ontario. 6. Government Contracts Regulations Exception The following exception to the Government Contracts Regulations is invoked for this procurement under subsection 6(d) - "only one person is capable of performing the work". 7. Exclusions and/or Limited Tendering Reasons The following exclusions and/or limited tendering reasons are invoked under the : Agreement on Internal Trade (AIT) Article 506.12 (a) World Trade Organization - Agreement on Government Procurement (WTO-AGP) Article XV.1 (d) North American Free Trade Agreement (NAFTA) Article 1016.2 (b) 8. Ownership of Intellectual Property Ownership of any Foreground Intellectual Property arising out of the proposed contract will vest in the Contractor. 9. Period of the proposed contract or delivery date The system must be delivered on 31st March 2016. 10.Name and address of the pre-identified supplier AB Sciex LP 71 Four Valley Drive Concord, Ontario L4K 4V8 Canada 11. Suppliers' right to submit a statement of capabilities Suppliers who consider themselves fully qualified and available to provide the goods, services or construction services described in the ACAN may submit a statement of capabilities in writing to the contact person identified in this notice on or before the closing date of this notice. The statement of capabilities must clearly demonstrate how the supplier meets the advertised requirements. 12. Closing date for a submission of a statement of capabilities The closing date and time for accepting statements of capabilities is 6th January 2016 at 2:00 p.m. EST. 13. Inquiries and submission of statements of capabilities Inquiries and statements of capabilities are to be directed to: Monique Gosselin Supply Specialist Public Works and Government Services Canada Scientific, Medical and Photographic Division - PV Portage III - Floor: 6A2 - Room: 48 11 Laurier Street Gatineau, Quebec Canada K1A 0S5 Telephone: 873-469-3194 Facsimile: 819-956-3814 E-mail: monique.gosselin@pwgsc.gc.ca Delivery Date: 17/12/2015 You are hereby notified that the government intends to negotiate with one firm only as identified above. Should you have any questions concerning this requirement, contact the contracting officer identified above. An Advance Contract Award Notice (ACAN) allows departments and agencies to post a notice, for no less than fifteen (15) calendar days, indicating to the supplier community that it intends to award a good, service or construction contract to a pre-identified contractor. If no other supplier submits, on or before the closing date, a Statement of Capabilities that meets the requirements set out in the ACAN, the contracting authority may then proceed with the award. However, should a Statement of Capabilities be found to meet the requirements set out in the ACAN, then the contracting authority will proceed to a full tendering process. Suppliers who consider themselves fully qualified and available to provide the services/goods described herein, may submit a statement of capabilities in writing to the contact person identified in this Notice on or before the closing date of this Notice. The statement of capabilities must clearly demonstrate how the supplier meets the advertised requirements. The PWGSC file number, the contracting officer's name and the closing date of the ACAN must appear on the outside of the envelope in block letters or, in the case of a facsimile transmission, on the covering page. The Crown retains the right to negotiate with suppliers on any procurement. Documents may be submitted in either official language of Canada.

SysCAD Plant Simulation Software

National Research Council Canada | Published October 11, 2017  -  Deadline October 26, 2017
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Trade Agreement: NAFTA / CFTA / FTAs with Peru / Colombia / Panama / Korea Tendering Procedures: All interested suppliers may submit a bid Non-Competitive Procurement Strategy: Exclusive Rights Comprehensive Land Claim Agreement: No Vendor Name and Address:  KWA Kenwalt Australia Pty Ltd KWA Kenwalt Australia P/L 6 Falcon Ave Australia 6018 Nature of Requirements:   SysCAD Plant Simulation Software  31184-178946/A Clark, Trevor Telephone No. - (819) 420-6324 Email: trevor.clark@tpsgc-pwgsc.gc.ca  REQUIREMENT:  The Energy, Mining and Environment (EME) portfolio of the National Research Council of Canada (NRC) has a requirement for the provision of goods as specified under "Background" below. The purpose of this Advance Contract Award Notice (ACAN) is to signal the government's intention to award a contract for these goods to KWA Kenwalt Australia Pty Ltd, the developer of the SysCAD Plant Simulation software. Before awarding a contract, however, the government would like to provide other suppliers with the opportunity to demonstrate that they are capable of satisfying the requirements set out in this Notice, by submitting a statement of capabilities during the 15 calendar day posting period.   If other potential suppliers submit a statement of capabilities during the 15 calendar day posting period that meet the requirements set out in the ACAN, the government will proceed to a full tendering process on either the government's electronic tendering service or through traditional means, in order to award the contract.  If no other supplier submits, on or before the closing date, a statement of capabilities meeting the requirements set out in the ACAN, a contract will be awarded to the pre-selected supplier.  BACKGROUND:  The Energy, Mining and Environment portfolio of the NRC is seeking to procure SysCAD software to further develop its process modeling capabilities for the hard-rock mining sector.  Public Works and Government Services Canada, on behalf of its Client, the National Research Council of Canada, intends to enter into a sole source contract with KWA Kenwalt Australia Pty Ltd, the developer of SysCAD for the purpose of procurement of the following:  Initial Requirement  1. Full Stand-Alone Steady State and Dynamic Transfer License with Energy Balance Add-On 2. 19 months of Software Upgrade and Maintenance 3. 5 day (40 hours) training course for Dynamic Transfer, including supply of temporary full licenses to all attendees  MINIMUM ESSENTIAL REQUIREMENTS  Any interested supplier must demonstrate by way of a statement of capabilities that it meets all of the mandatory requirements in Annex A.    JUSTIFICATION FOR THE PRE-SELECTED SUPPLIER   The reasons for single tendering are described in Annex A.  Section 6 of the Government Contract Regulations is being invoked in this procurement as only one person or firm is capable of performing the contract.  CFTA, Article 513, paragraph 1.(b) and 1.(c) are applicable on the basis of limited tendering due to compatibility with existing products, to recognize exclusive rights, such as exclusive licenses, copyright and patent rights, or to maintain specialized products that must be maintained by the manufacturer or its representative, and when there is an absence of competition for technical reasons and the goods or services can be supplied only by a particular supplier and no alternative or substitute exists.  Articles 1016.2(b) and 1016.2(d) of NAFTA are applicable on the basis of limited tendering due to reasons where, for works of art, or for reasons connected with the protection of patents, copyrights or other exclusive rights, or proprietary information or where there is an absence of competition for technical reasons, the goods or services can be supplied only by a particular supplier and no reasonable alternative or substitute exists, for additional deliveries by the original supplier that are intended either as replacement parts or continuing services for existing supplies, services or installations, or as the extension of existing supplies, services or installations, where a change of supplier would compel the entity to procure equipment or services not meeting requirements of inter changeability with already existing equipment or services, including software to the extent that the initial procurement of the software was covered by this Chapter.  PERIOD OF CONTRACT  The proposed contract is for the purchase of a single SysCAD Stand-Alone Steady State and Dynamic Transfer License with Energy Balance Add-On and associated maintenance and support services for a period of 19 months from date of Contract Award.      ANNEX A  The reasons for sole source procurement of the required metallurgical plant simulation software are listed below. The Energy, Mining and Environment (EME) portfolio of the National Research Council of Canada (NRC) requires the solution to be compliant with the following functionalities:  ESSENTIAL SOFTWARE REQUIREMENTS:  General M1 The software solution must be "commercial-off-the-shelf", meaning that each component of software is commercially available and requires no further research and development and is part of an existing product line with a field-proven operational history (that is, it has not simply been tested in a laboratory or experimental environment).  M2 The software solution must natively operate in a Microsoft Windows environment (Windows 7 or newer). The software must also function with Mac OS X (Mavericks or newer) where Parallels Desktop (Version 12 or newer) (http://www.parallels.com) or similar is installed with a Windows virtual machine.  M3 The software solution license must be provided on a USB License Key Dongle for easy license transfer between multiple instances of the software solution installed on multiple machines.  M4 The software solution must have a runtime licensing option.   M5 The software solution solver must support and utilize multi-core computing functionality (quad-core processor or better) to enable parallel processing.  M6 The software solution must have functionality to natively import data to and export data from Microsoft Excel files.  M7 The software solution must have the functionality to simulate metallurgical plants and ancillary utilities and have an extensive library of metallurgical unit operations models.  M8 The vendor must provide an extensive on-line documentation, including detailed description of models employed, and video tutorials with detailed examples to support training, model development and troubleshooting.  M9 The software solution must be accompanied by fully functional demo example projects, including, but not limited to gold leaching circuit, hydrometallurgical Ni/Cu flowsheet, Cu smelting (flash furnace, FEM blast furnace) examples, lithium carbonate acid leach, SX and IX circuits, pressure leach (with preheaters and flash train), absorption tower, evaporator flash train including MVR example, counter-current decantation train, power plant, water treatment plant, desalination plant, sorting facility. Dynamic demonstration examples should include dynamic tank with a reaction and controls, material storage, shipping and production planning model, continuous materials handling coupled with a process area operating at batch.   M10 The software solution must have a graphical representation of a process flow diagram. The graphical representation of a process must display unit operations using the industry accepted symbols and formats and should not require any additional process flowsheet drafting. The user must have the capability to insert flowsheet border and name process flowsheet areas.  M11 The software solution must have a native functionality to manage and edit existing unit operation symbols as well as ability to import flowsheets and new graphics symbols in the *.DFX format created using commercial  Computer-aided design (CAD) packages (e.g. AutoCAD, MicroStation).  M12 The software solution must have native functionality to "Copy and Paste" parts of flow graphical flowsheet model. The "Copy and Paste" operation must be able to generate new model tags to avoid conflicts between the original and the pasted copy.  M13 The software solution must have the functionality to natively import species data from the HSC Chemistry Thermodynamic Database, developed by Outotec (http://www.hsc-chemistry.com/)  M14 The software solution must have functionality to generate simulation reports in Microsoft Excel 10 or newer using specified key words or value tag format on any number of Excel sheets, any number of times and locations.  M15 The software solution must have a command script function to batch run multiple SysCAD simulations using a set of model conditions specified in Microsoft Excel files and generate corresponding reports in Microsoft Excel.  M16 The software solution must have a general purpose process controller that can be used to simulate sophisticated plant control functions and perform user defined calculations using a programing syntax similar to VBA. The software solution must have the functionality to run custom (used-defined) sub-routines, execute user-defined functions that include, but are not limited to, loops, comparison/logic operations, counters, etc. using process variables within any unit or stream. The controller code file must be a stand-alone text file that can be created and edited using Notepad or similar text editor. The user must have an ability to add access window tab for the custom controller that displays input parameters and calculation results.        M17 The software solution must have a Proportional-Integral-Derivative (PID) controller that can be used in combination with a transmitter linked to an actuator to simulate process controls including interlocks, sequencing operations and test different control strategies.  M18 The software solution must have native functionality to display and plot selected process variables and key performance indicators (e.g. set points convergence) in real-time from any flowsheet in the project in both steady-state and dynamic modes.  M19 The software solution must use the International Association for Properties of Water and Steam (IAPWS) Industrial Formulation (IAPWS-IF97) for calculating thermodynamic properties of water and steam. See IAPWS website for additional information (www.iapws.org).   M20 The software solution must use the IAPWS 2008 formulation for composition and calculation of thermophysical properties of seawater and concentrated brines as described in "Release on the IAPWS Formulation 2008 for the Thermodynamic Properties of Seawater". See IAPWS website for additional information (www.iapws.org).  M21 The software solution must have Gibbs free energy minimization functionality for calculating product stream composition.  M22 The software solution must have the capability to define solubility for chemical species as functions of temperature or mass fraction.  M23 The software solution must have the capability to automatically apply phase change and Vapor-Liquid Equilibria (VLE) transformations to model components based on defined thermophysical data.  M24 The software solution must have the capability to automatically calculate boiling point elevation (BPE) for aqueous solutions based on vant Hoffs constants.  M25 The software solution must have the capability to automatically calculate the extent of reactions when simulating Solvent Extraction unit operation based on user-defined equilibrium isotherm according to the McCabe-Thiele method.  M26 The software solution must utilize text files to define chemical reactions, their extent and sequence using either built-in reaction editor or any text editor such as Notepad or equivalent.  M27 The software solution must have the capability to "drag-and-drop" one reaction file to another when using the default reaction editor.  M28 The software solution must have the capability to designate reaction species as source only, recycle only or source and recycle when modeling reaction sequences.  M29 The software solution must have the capability of automatically performing acidity (pH) calculations for aqueous streams based on default or user-defined acid-base dissociation constants (including multiprotic acids/bases, e.g. H2SO4, H3PO4, H2CO3, Ca(OH)2).   M30 The software solution must have the capability of automatically calculating and displaying process water quality parameters, such as alkalinity, free mineral acidity, hardness (total, Ca, Mg), total dissolved solids, total carbon, total organic carbon, chemical oxygen demand.  M31 The software solution must have the capability to simulate plants downtime due to minor and major equipment maintenance using probabilistic models with user-defined time constants.  M32 The software solution must have the capability to add random disturbances to a dynamic model using a set of probability density functions with user-defined coefficients.  M33 The software solution must have the capability to specify changes in model variables with time such as seasonal climate data etc.   M34 The software solution must have the ability to collect, process and output statistical information when running in a dynamic mode, including bivariate statistics, flow statistics, control variables statistics (e.g. tank levels, etc.)  M35 The software solution must be expandable to include OPC (OLE for Process Control) functionality for connectivity with Programmable Logic Controllers (PLCs) and Distributed Control Systems (DCSs).   CLOSING DATE AND TIME FOR WRITTEN SUPPLIER RESPONSES CHALLENGING THIS REQUIREMENT IS 14:00 p.m. EST, October 26, 2017.  You are hereby notified that the Government intends to solicit a bid and negotiate with one firm only as identified above.   If you wish to submit a written response showing that you are capable of meeting this requirement, it must be done not later than the specified closing date and time. The file number, contracting officer's name, and the closing date of the ACAN must appear on the outside of the envelope in block letters on the covering page. As it is intended to proceed in a timely manner, responses received after the closing date will not be considered.  Responses received on or before the closing date will be considered solely for the purpose of deciding whether or not to conduct a competitive procurement. Information provided will be used by the Crown for technical evaluation purposes only and is not to be construed as a competitive solicitation. Your written response must provide sufficient evidence (e.g. specifications, technical data, drawings, or any other proof) that clearly demonstrates that your product or service is capable of fulfilling this requirement.  Suppliers that have submitted a response will be notified in writing of PWGSC's decision to continue with the non-competitive procurement or compete the requirement.   Delivery Date: Above-mentioned  You are hereby notified that the government intends to negotiate with one firm only as identified above. Should you have any questions concerning this requirement, contact the contracting officer identified above.  An Advance Contract Award Notice (ACAN) allows departments and agencies to post a notice, for no less than fifteen (15) calendar days, indicating to the supplier community that it intends to award a good, service or construction contract to a pre-identified contractor. If no other supplier submits, on or before the closing date, a Statement of Capabilities that meets the requirements set out in the ACAN, the contracting authority may then proceed with the award.  However, should a Statement of Capabilities be found to meet the requirements set out in the ACAN, then the contracting authority will proceed to a full tendering process.  Suppliers who consider themselves fully qualified and available to provide the services/goods described herein, may submit a statement of capabilities in writing to the contact person identified in this Notice on or before the closing date of this Notice. The statement of capabilities must clearly demonstrate how the supplier meets the advertised requirements.  The PWGSC file number, the contracting officer's name and the closing date of the ACAN must appear on the outside of the envelope in block letters or, in the case of a facsimile transmission, on the covering page.  The Crown retains the right to negotiate with suppliers on any procurement.  Documents may be submitted in either official language of Canada.

Hybrid Modelling to generate annual and daily source contributions and ambient concentrations for NO2, PM2.5, and O3 at a high spatial resolution (≤1 km) across Canada

Health Canada | Published June 8, 2017  -  Deadline July 18, 2017
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NOTICE OF PROPOSED PROCUREMENT (NPP)

Solicitation #: 1000191423 Closing Date: July 18, 2017 Time: 2 p.m. EDT

This requirement is for the department of Health Canada.

Title:  Hybrid Modelling to generate annual and daily source contributions and ambient concentrations for NO2, PM2.5, and O3 at a high spatial resolution (≤1 km) across Canada

Scope:

Land use regression (LUR) models developed internally and externally by Health Canada under the Clean Air Regulatory Agenda (CARA) have been widely used to estimate exposure in air pollution health studies due to their high spatial resolution (e.g., 5 m). However, LUR models lack temporal resolution, limiting their ability to provide short term (e.g., daily) and historic estimates of exposure. In contrast, chemical transport models (CTMs) such as the Community Multiscale Air Quality Model (CMAQ) and the Global Environmental Multi-scale - Modelling Air quality and Chemistry (GEM-MACH) have been used to predict pollutant concentrations at very fine temporal resolution (e.g., hourly) and can provide critical information attributing ambient concentrations with major source sectors. However, the spatial resolution of CTM models is too coarse to detect within-city pollutant gradients relevant for health studies. This contract will develop hybrid models as follows:

1) Generating longitudinal data including source specific emissions and meteorology data;

2) Using longitudinal emissions and meteorology data to develop hybrid models (as defined above) for NO2 and PM2.5 from 2000-2012 based on local and national LUR models combined with CMAQ;

3) Applying hybrid models to estimate source specific contributions (i.e., gasoline, diesel, biomass burning, and multiple industrial sectors identified by the direct decoupled method in CMAQ) to ambient concentrations of NO2, PM2.5, and O3 from 2000-2012; and

4) Comparing hybrid model outputs with results obtained from source apportionment of ground level monitoring data, as well as oxidative potential and PM component models. Source apportionment and oxidative potential results will be provided by Health Canada. PM component results will be obtained by the contractor from Dalhousie University.

The contractor will develop national hybrid models to provide historic estimates for NO2, PM2.5, and source attribution from 2000-2012, including annual and short term concentrations for each year. The contractor will also provide high resolution historic and short term estimates for all urban areas in Canada with local LUR models (approximately 14 cities). The contractor will develop national CMAQ models to provide historic estimates and source attribution for O3 from 2000-2012, including annual and short term concentrations for each year.

The data generated by this work will be used to estimate historic and short term exposure to NO2 and PM2.5, as well as source contributions, which are needed for future CARA funded health studies led by Health Canada in collaboration with external partners. National hybrid model estimates will allow for characterization of differential health risks associated with gasoline, diesel, and different industrial source sectors, and short term health effects across Canada (including urban vs rural health risks) by providing exposure estimates in areas that are not located near a National Air Pollution Surveillance (NAPS) station.

Objectives of the Requirement

The Hybrid Modelling Contract will generate annual and daily source contributions and ambient concentrations for NO2, PM2.5, and O3 at a high spatial resolution (≤1km) across Canada to support Health Canada’s longitudinal exposure assessment in national health studies. 

Health Canada requires these hybrid model estimates for future health studies—i.e., for linkage with longitudinal cohorts examining health effects across every life stage from fetal development to aging populations, as well as in national time series studies examining health impacts in both urban and rural populations. Finally, exposure and risk estimates derived from the hybrid modeling contract will be compared with other approaches to inform policy development. 

Estimated Value:

The three-year contract, plus two option years, shall not exceed $345,000.00 plus tax, in total.

Ownership of Intellectual Property:

The Contractor shall own the Intellectual Property developed under the contract.

Security Requirement:

There is no security requirement.

Mandatory Requirements:

M1. The bidder must provide evidence in the proposal that the proposed Project Manager or Principal Investigator has a doctorate in one of the following fields: environmental engineering, atmospheric chemistry, or atmospheric physics, with a specialization relevant to this project and at least five years of experience using atmospheric air quality modeling or chemical transport models to generate ground-level ambient air quality estimations for two or more of the pollutants of interest (i.e. must have 1&2, 1&3 or 2&3):

1) nitrogen oxides (NOx) or nitrogen dioxide (NO2),

2) fine particulate matter (PM2.5) including primary and secondary fine PM , and

3) ozone (O3).

M2. The bidder must provide evidence in the proposal that the team includes at least one recognized expert with at least five years of experience in the use of Community Multiscale Air Quality Model (CMAQ) to predict ground-level ambient air pollution concentrations for two or more of the pollutants of interest in Canada (i.e. must have 1&2, 1&3 or 2&3):

1) nitrogen oxides (NOx) or nitrogen dioxide (NO2),

2) fine particulate matter (PM2.5) including primary and secondary fine PM2.5 , and

3) ozone (O3).

M3.  The bidder must provide evidence in the proposal that the team includes at least one team member with at least three years of experience in the use of the Decoupled Direct Method (DDM) in conjunction with atmospheric air quality modeling to conduct sensitivity analyses and / or source attribution for at least two of the pollutants of interest (i.e. must have 1&2, 1&3 or 2&3):

1) nitrogen oxides (NOx) or nitrogen dioxide (NO2),

2) fine particulate matter (PM2.5) including primary and secondary fine PM2.5 , and

3) ozone (O3).

M4.  The bidder must provide evidence in the proposal that the team includes at least one team member with at least two years of experience generating national and local hybrid air quality models that:

  • combine local and national land use regression models in Canada with CMAQ or GEM-MACH – using CMAQ or GEM-MACH data with spatial resolution of ≤15 km and temporal resolution of ≤ 1 day, producing hybrid model surfaces with a spatial resolution of ≤1 km and temporal resolution of ≤ 1 day to
  • estimate ground level ambient air quality for at least two of the following pollutants in Canada (i.e. must have 1&2, 1&3 or 2&3):
  1. nitrogen oxides (NOx) or nitrogen dioxide (NO2),
  2. fine particulate matter (PM2.5), and
  3. ozone (O3).
     

M5. The bidder must provide evidence in the proposal that the team includes at least one team member with at least one year of experience using Global Environmental Multiscale model - Modelling Air quality and CHemistry (GEM-MACH) to run air quality simulations and generate air pollution estimates for one or more of the pollutants of interest (i.e. must have 1, 2 or 3):

1) nitrogen oxides (NOx) or nitrogen dioxide (NO2),

2) fine particulate matter (PM2.5), and

3) ozone (O3).

Selection Methodology

The contract will be awarded to the bidder with the highest technical score, who can perform the work within the budget of $345,000.

Enquiries regarding this Request for Proposals are to be submitted in writing to:

Robert Merrick

Contracting Authority

E-mail:  Robert.Merrick@hc-sc.gc.ca

EQUINE DRUG TESTING SERVICES

Public Works & Government Services Canada | Published October 3, 2014
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DESCRIPTION : The Canadian Pari-Mutuel Agency (CPMA) of Agriculture and Agri-Food Canada (AAFC) is a federal regulatory agency with a mandate to regulate and supervise pari-mutuel betting in Canada on horse racing, with the objective of ensuring that pari-mutuel betting is conducted in a way that is fair to the betting public. One of the key activities undertaken by the CPMA in advancing this mandate is the operation of a national drug control program in accordance with the Pari-Mutuel Betting Supervision Regulations (the Regulations) (http://laws.justice.gc.ca/en/showtdm/cr/SOR-91-365) enacted under the Criminal Code aimed at preventing and detecting the use of prohibited drugs and medication in race horses. In this regard the CPMA requires the services of a laboratory that will become an “Official Laboratory” as defined under Section 2 of the Regulations. This designated Official Laboratory will provide services to prevent and detect the uncontrolled use of drugs and medications in racing horses, through: (1) analytical services in respect of official samples of equine body fluids and other materials obtained from horses racing in pari-mutuel races at Canadian racetracks; and, (2) research services on an “as and when requested” basis, with respect to the detection and identification of drugs and metabolites in horses through the analysis of urine and blood obtained from horses which have been administered drugs under controlled conditions. Services will be required for a period commencing from date of contract award (estimated to be from April 1, 2015) up to and including March 31, 2018, with an irrevocable option on the part of Canada to extend the contract period of any resultant contract by up to two (2) additional one (1) year periods. OFFICIAL LABORATORY : The successful Bidder’s laboratory will be designated by the Executive Director of the CPMA as an Official Laboratory under the Pari-Mutuel Betting Supervision Regulations (the Regulations). In order to be designated as the CPMA’s “Official Laboratory”, the Contractor must be accredited by the Standards Council of Canada (SCC) as described in Appendix 2 of Annex A of this RFP. In the case that the successful Bidder’s laboratory is accredited under ISO/IEC 17025 in the Forensic Testing Program specialty area as a Drug Chemistry or Toxicology laboratory (CAN-P-1578, Appendices 1 & 6) but not as an Equine Drug Testing laboratory, the Bidder must successfully complete a scope expansion to cover Equine Drug Testing (CAN-P-1578 Appendix 4) prior to Contract Award. At Bid closing, the Bidder must demonstrate that the laboratory proposed to carry out the Work has submitted a request for scope expansion to cover Equine Drug Testing (CAN-P-1578) to the Standards Council of Canada and must provide a copy of the Standards Council of Canada’s acknowledgement to the request. TRADE AGREEMENTS : The requirement is subject to the provisions of the Agreement on Internal Trade (AIT). The requirement is for Commercial Testing Laboratory Services (GSIN: H300C) which are excluded from the application of the North American Free Trade Agreement (NAFTA) as per Annex 1001.1b-2, Class H3, Inspection Services (incl. Commercial Testing Laboratory Services except Medical/Dental). The requirement is excepted from the application of World Trade Organization - Agreement on Government Procurement (WTO-AGP) under Article XXIII, Exceptions to the Agreement, as follows; “subject to the requirement that such measures are not applied in a manner which would constitute a means of arbitrary or unjustifiable discrimination between countries where the same conditions prevail or a disguised restriction on international trade, nothing in this Agreement must be construed to prevent any Party from imposing or enforcing measures: necessary to protect public morals, order or safety...” The Comprehensive Land Claims Agreements (CLCAs) are not applicable to this procurement, as the Work will not be delivered to, nor conducted within CLCA areas. INTELLECTUAL PROPERTY : Canada will own the Intellectual Property Rights in Foreground Information as per 6.4.1 'the main purpose of the Contract and deliverables contract is to generate knowledge and information for public dissemination'. MANDATORY TECHNICAL EVALUATION CRITERIA : Any Bid that fails to meet the Mandatory Requirements stipulated below will be deemed non-responsive and will be given no further consideration. At Bid closing time, the Bidder must comply with the Mandatory Requirements. The Bidder is required to provide the necessary documentary evidence to support compliance. The Contracting Authority may request any supporting documentation from the Bidder to validate, demonstrate or support the Bidder’s compliance with any of the criteria listed below prior to Contract Award. Failure to comply with the request of the Contracting Authority will render the bid non-responsive. A resource may only be proposed for a single Category of work. A resource can be proposed as either a technical support personnel or a research technician but not both. Listing experience without providing any supporting data to describe where, when and how such experience was obtained may result in the experience not being included for evaluation purposes. MR-1. At Bid Closing, the Bidder’s laboratory proposed to perform the work must be accredited by the Standards Council of Canada (SCC) under ISO/IEC 17025 in the Forensic Testing Program specialty area as a Forensic Equine Drug Testing laboratory (CAN-P-1578, Appendix 4); OR, At Bid Closing, the Bidder’s laboratory proposed to perform the work must be accredited under ISO/IEC 17025 in the Forensic Testing Program specialty area as a Drug Chemistry or Toxicology laboratory (CAN-P-1578, Appendices 1 & 6) with a scope that includes analytical instrumentation and methodology for the analysis of drugs included in (but not limited to) the Schedule to the Pari-Mutuel Betting Supervision Regulations, according to Part V of the Regulations (http://laws.justice.gc.ca/eng/regulations/sor-91-365/index.html). In the case that the successful Bidder’s laboratory is accredited under ISO/IEC 17025 in the Forensic Testing Program specialty area as a Drug Chemistry or Toxicology laboratory (CAN-P-1578, Appendices 1 & 6) but not as an Equine Drug Testing laboratory, the Bidder must successfully complete a scope expansion to cover Equine Drug Testing (CAN-P-1578 Appendix 4) prior to Contract Award. The Bidder must provide a copy of the Bidder’s accredited scope and accreditation certificate for Forensic Equine Drug Testing (CAN-P-1578, Appendix 4), Drug Chemistry (CAN-P-1578, Appendix 1) or Toxicology (CAN-P-1578, Appendix 6). In the case that the Bidder’s laboratory proposed to perform is accredited under ISO/IEC 17025 in the Forensic Testing Program specialty area as a Drug Chemistry or Toxicology laboratory (CAN-P-1578, Appendices 1 & 6), the Bidder must demonstrate and provide evidence that, no later than the date of Bid Closing, the laboratory proposed to carry out the Work has submitted a request for scope expansion to cover Equine Drug Testing (CAN-P-1578) to the Standards Council of Canada and must also provide a copy of the Standards Council of Canada’s acknowledgement to the request. MR-2. The Bidder must provide a current curriculum vitae (CV) for the individuals proposed and a reference contact to validate the information in the CV for each resource described below: • a minimum of three Analytical Chemists; • a minimum of three Technical Support Personnel for the analysis of official samples on a daily basis; • two Research Scientists; • two Research Technicians; and, • one Quality Manager. Reference checks may be conducted to validate information provided in the curriculum vitae only. MR-3. The Bidder must provide Standard Operating Procedures (SOPs) from the laboratory proposed to perform the Work for the operation of the following analytical instruments to use for detection and confirmation of scheduled drugs: • High performance liquid chromatography - mass spectrometry (HPLC/MS/MS) • Enzyme-linked immunosorbent assay (ELISA (automated plate reader)) • High performance liquid chromatography - fluorescence detection (HPLC/FL) MR-4. Analytical Chemists (3) The Bidder’s laboratory proposed to perform the Work must provide the services of a minimum of three (3) analytical chemists who are each eligible to be designated by the Executive Director of the CPMA as an Official Chemist as per the Regulations. Prerequisites to be eligible for designation as an Official Chemist are included below. For each proposed Analytical Chemist the Bidder must provide evidence of (the Bidder is requested to use the Experience Description Form 1.1, “MR-4 : Analytical Chemist” provided in Attachment 1 to Part 4): a) at a minimum, a Bachelor’s degree in a chemical science from a recognized Canadian university, or the equivalent as established by a recognized Canadian academic credentials assessment service*, if obtained outside Canada. The Bidder must submit a copy of the degree; and, *The list of recognized assessment organizations can be found under the Canadian Information Centre for International Credentials website, at the following internet link: http://www.cicic.ca/indexe.stm. b) a minimum of three (3) years of practical experience within the last five (5) years measured back from the date of Bid Closing in analytical procedures using HPLC-MS-MS, with experience in any combination of pharmacology, pharmaceutical chemistry, analytical or forensic toxicology, biopharmaceutics or medicinal chemistry; and, c) a minimum of one (1) year continuous employment within the last two (2) years measured back from the date of Bid Closing in a capacity directly involved on a day-to-day basis with the analysis of samples in a laboratory that has been accredited by the Standards Council of Canada under ISO/IEC 17025 in the Forensic Testing Program specialty area as a Forensic Equine Drug Testing laboratory (CAN-P-1578 Appendix 4); or, a Laboratory that has been accredited under ISO/IEC 17025 in the Forensic Testing Program specialty area as a Drug Chemistry or Toxicology laboratory (CAN-P-1578, Appendices 1 and 6). The first three resources proposed listed sequentially will be evaluated. Additional resources proposed will not be evaluated for the purposes of the Technical Evaluation, however, all resources will be required to meet the minimum qualifications detailed under the Statement of Work. MR-5. Technical Support Personnel (3) The Bidder’s laboratory performing the Work must provide the services of a minimum of three technical support personnel for the analysis of official samples on a daily basis. For each proposed Technical Support Personnel the Bidder must provide evidence of (the Bidder is requested to use the Experience Description Form 1.2, “MR-5: Technical Support Personnel” provided in Attachment 1 to Part 4): a) at a minimum, a college diploma in a chemistry-related field from a recognized academic institution. The Bidder must submit a copy of the diploma; and, b) a minimum of two (2) years experience within the last five (5) years measured back from the date of bid closing in a chemistry-related field. The first three resources proposed listed sequentially will be evaluated. Additional resources proposed will not be evaluated for the purposes of the Technical Evaluation, however, all resources will be required to meet the minimum qualifications detailed under the Statement of Work. MR-6. Research Scientist (2) The Bidder must provide the services of two Research Scientists to perform research and method development according to specifications and project requirements of the CPMA described in the Statement of Work at Annex A. For each proposed Research Scientist the Bidder must provide evidence of (the Bidder is requested to use the Experience Description Form 1.3, “MR-6 : Research Scientist” provided in Attachment 1 to Part 4): a) at a minimum, a doctoral degree (PhD) in a chemical science related field from a recognized Canadian University, or the equivalent as established by a recognized Canadian academic credential assessment service*, if obtained outside Canada. The Bidder must submit a copy of the degree; and, *The list of recognized assessment organizations can be found under the Canadian Information Centre for International Credentials website, at the following internet link: http://www.cicic.ca/indexe.stm b) a minimum of three (3) years experience within the last five (5) years measured back from the date of bid closing in development of analytical methods involving HPLC-MS-MS for pharmaceutical substances in body fluids; and, c) a minimum of three (3) scientific publications authored by the proposed Research Scientist demonstrating evidence of experience in chemical science research within the last five (5) years measured back from the date of bid closing. A list of Publication references or a copy of the Publications must be submitted. The first two resources proposed listed sequentially will be evaluated. Additional resources proposed will not be evaluated for the purposes of the Technical Evaluation, however, all resources will be required to meet the minimum qualifications detailed under the Statement of Work. MR-7. Research Technician (2) The Bidder must provide the services of two Research Technicians to provide support in the research and method development activities according to specifications and project requirements of the CPMA described in the Statement of Work at Annex A. For each proposed Research Technician the Bidder must provide evidence of (the Bidder is requested to use the Experience Description Form 1.4, “MR-7: Research Technician” provided in Attachment 1 to Part): a) at a minimum, a college diploma in a chemistry-related field from a recognized Canadian academic institution, or the equivalent as established by a recognized Canadian academic credential assessment service*, if obtained outside Canada. The Bidder must submit a copy of the diploma; and *The list of recognized assessment organizations can be found under the Canadian Information Centre for International Credentials website, at the following internet link: http://www.cicic.ca/indexe.stm b) a minimum of two (2) consecutive years experience within the last five (5) years measured back from the date of bid closing in a chemical-related field. The first two resources proposed listed sequentially will be evaluated. Additional resources proposed will not be evaluated for the purposes of the Technical Evaluation, however, all resources will be required to meet the minimum qualifications detailed under the Statement of Work. MR-8. Quality Manager (1) The Bidder’s laboratory performing the Work must provide the services of one Quality Manager. For the proposed Quality Manager the Bidder must provide evidence of (the Bidder is requested to use the Experience Description Form 1.5, “MR-8 : Quality Manager” provided in Attachment 1 to Part 4): a) training in ISO/IEC 17025 and internal auditing*; and, b) a minimum of one (1) year of current and consecutive experience measured back from the date of bid closing as a Quality Manager. *Acceptable evidence is a Certificate of Training by a recognized institution in this field e.g. Academia Qualitas, Standard Council of Canada and Curriculum vitae. The first resource proposed listed sequentially will be evaluated. Additional resources proposed will not be evaluated for the purposes of the Technical Evaluation, however, all resources will be required to meet the minimum qualifications detailed under the Statement of Work. POINT RATED TECHNICAL EVALUATION CRITERIA : Point Rated Technical Evaluation Criteria are included in Part 4 of the bid solicitation. BASIS OF SELECTION : Basis of Selection - Highest Combined Rating of Technical Merit and Price 1. To be declared responsive, a bid must: (a) comply with all the requirements of the bid solicitation; and, (b) meet all mandatory criteria; and, (c) obtain the required minimum of 220 points out of a total of 294 points for criterion PR-1, and the minimum required score must be achieved in each sub criterion in order to be considered responsive; and, (d) obtain the required minimum of 86 points out of a total of 115 available points (75%) for criteria PR-2 to PR-6; and, (e) comply with the Laboratory Facility Evaluation Visit Checklist; and, (f) demonstrate that all proposed Chemists have successfully passed the Chemist Qualification Test; and, (g) demonstrate that the proposed Laboratory has successfully completed a scope expansion to cover Forensic Equine Drug Testing in accordance with CAN-P-1578, Appendix 4. 2. Bids not meeting items (a) or (b) or (c) or (d) or (e) or (f) or (g) will be declared non-responsive. 3. The selection will be based on the highest responsive combined rating of technical merit and price. The ratio will be 70% for the technical merit and 30% for the price. CONTRACTING AUTHORITY : Heather Wilson Supply Specialist Public Works and Government Services Canada Acquisitions Branch Science Procurement Directorate Place du Portage, Phase III, 11C1 11 Laurier Street Gatineau, Quebec K1A 0S5 Telephone: (819) 956-1354 Facsimile: (819) 997-2229 E-mail address: Heather.Wilson@tpsgc-pwgsc.gc.ca All enquiries must be submitted in writing to the Contracting Authority no later than ten (10) calendar days before the bid closing date.

In Vitro Pharmacokinetics for High Throughput Data Interpretation

Health Canada | Published January 11, 2016
Winner
Paraza Pharma, Inc.
cpvs

NOTICE OF PROPOSED PROCUREMENT (NPP) Solicitation #: 1000175432 Closing Date: November 30, 2015 Time: 2 p.m. EDT This requirement is for the department of Health Canada. Title: In Vitro Pharmacokinetics for High Throughput Data Interpretation Scope: As part of a project funded by Canada’s Chemicals Management Plan (CMP) research fund, Health Canada research and regulatory scientists are developing tools and approaches to facilitate the use of in vitro studies and dosimetry to establish points of departure for risk assessment. The data generated through this contract will be used to assist in developing predictive tools and informing the utility of non-traditional toxicity data for regulatory use. Specifically, the development of tools to interpret and evaluate high-priority compounds that will assist evaluation programs within Health Canada in assessing the results of the high throughput data and contribute to informed screening and risk assessment of CMP chemicals. The list of CMP cycle 3 substances included in the first experimental batch (See Table in RFP) represent substances that the Existing Substances Risk Assessment Bureau has identified as early data needs to support methods development and risk assessment activities. The pharmacokinetic parameters generated through this work fulfill a data-need priority for advancing our understanding for the integration of high throughput screening data into CMP. Specifically, the ethyl glycol ethers and hindered-substance groupings are currently being considered as an early assessment grouping under the upcoming phase of CMP cycle 3 assessment. Assessment-specific timelines will become available in winter 2015-16. In addition to assessment activities, the substances are part of a larger research collaboration between the Environmental Health Science Research Bureau, Existing Substances Risk Assessment Bureau, and the US EPA National Center of Computational Toxicology. The in vitro pharmacokinetic parameters will be used to develop in vitro- to-in vivo extrapolation methods using pharmacokinetic models, high throughput data, chemo-informatics approaches, and available published health endpoints. An important deliverable of this collaboration is the development of a case study that will address several key elements, including uncovering the considerations of using high throughput data to develop categories and to evaluate the advantages and uncertainties associated with read-across. Further substances comprising a second list will continue to be added for data generation as they are prioritized for assessment and/or are identified as being ideal candidates to support the development of predictive tools. Objectives of the Requirement The aim of this project is to conduct in vitro experiments to generate the pharmacokinetic parameters (microsomal metabolic stability and blood protein binding) for a series of chemicals identified by the Existing Substances Risk Assessment Bureau (ESRAB). Table 1 presents the first batch of chemical to be analyzed and a second batch of chemicals will be identified before the end of fiscal year 2015-2016. The resulting data will subsequently support the needed computational in vitro-to-in vivo extrapolation (IVIVE) methods which will then be used to estimate human equivalent doses. The data obtained from these pharmacokinetic evaluations will be used to facilitate the addition of a risk context to the high-throughput in vitro screening data. Estimated Value: The overall value of the requirement, including the cost of the professional services, equipment, miscellaneous costs, and any other costs which will be associated with the requirement is estimated at $85,000 in fiscal year 2015-16, with an option estimated at $55,000 in fiscal year 2016-17). The total estimated value of the requirement over 2 fiscal years is $140,000. Ownership of Intellectual Property: Canada will own the Intellectual Property. Security Requirement: There is no security requirement. Mandatory Requirements: M1. The bidder’s project team must have a team leader with PhD in a biomedical sciences field and analytical expert with a PhD relevant to the work described in the Statement of Work. M2. The bidder’s project leader must demonstrate that within the last 5 years, they have undertaken projects to measure drug metabolism pharmacokinetic parameters using of in vitro analysis. M3. The bidder must have at least 5 years of experience in conducting drug metabolism pharmacokinetics studies. M4. The bidder must have at least 5 years of experience employing high end analytical techniques to assess in vitro experiments. M5. The bidder must clearly outline the methods that will be employed to meet the technical requirements described in the Statement of Work. Proposed methods must be clearly described, consistent with the SOW’s requirements, and be sufficiently detailed so as to demonstrate the bidder’s overall competence, experience and grasp of the required services. Selection Methodology The contract will be awarded to the bidder with the highest technical score who stays within the budget of $85,000 for this fiscal year (FY2015-16) and $55,000 for the option year FY2016-17. The total budget for this requirement, including the option year, is $140,000. Enquiries regarding this Request for Proposals are to be submitted in writing to: Robert Merrick Contracting Authority E-mail: Robert.Merrick@hc-sc.gc.ca

In Vitro Pharmacokinetics for High Throughput Data Interpretation

Health Canada | Published October 20, 2015  -  Deadline November 30, 2015
cpvs

NOTICE OF PROPOSED PROCUREMENT (NPP) Solicitation #: 1000175432 Closing Date: November 30, 2015 Time: 2 p.m. EDT This requirement is for the department of Health Canada. Title: In Vitro Pharmacokinetics for High Throughput Data Interpretation Scope: As part of a project funded by Canada’s Chemicals Management Plan (CMP) research fund, Health Canada research and regulatory scientists are developing tools and approaches to facilitate the use of in vitro studies and dosimetry to establish points of departure for risk assessment. The data generated through this contract will be used to assist in developing predictive tools and informing the utility of non-traditional toxicity data for regulatory use. Specifically, the development of tools to interpret and evaluate high-priority compounds that will assist evaluation programs within Health Canada in assessing the results of the high throughput data and contribute to informed screening and risk assessment of CMP chemicals. The list of CMP cycle 3 substances included in the first experimental batch (See Table in RFP) represent substances that the Existing Substances Risk Assessment Bureau has identified as early data needs to support methods development and risk assessment activities. The pharmacokinetic parameters generated through this work fulfill a data-need priority for advancing our understanding for the integration of high throughput screening data into CMP. Specifically, the ethyl glycol ethers and hindered-substance groupings are currently being considered as an early assessment grouping under the upcoming phase of CMP cycle 3 assessment. Assessment-specific timelines will become available in winter 2015-16. In addition to assessment activities, the substances are part of a larger research collaboration between the Environmental Health Science Research Bureau, Existing Substances Risk Assessment Bureau, and the US EPA National Center of Computational Toxicology. The in vitro pharmacokinetic parameters will be used to develop in vitro- to-in vivo extrapolation methods using pharmacokinetic models, high throughput data, chemo-informatics approaches, and available published health endpoints. An important deliverable of this collaboration is the development of a case study that will address several key elements, including uncovering the considerations of using high throughput data to develop categories and to evaluate the advantages and uncertainties associated with read-across. Further substances comprising a second list will continue to be added for data generation as they are prioritized for assessment and/or are identified as being ideal candidates to support the development of predictive tools. Objectives of the Requirement The aim of this project is to conduct in vitro experiments to generate the pharmacokinetic parameters (microsomal metabolic stability and blood protein binding) for a series of chemicals identified by the Existing Substances Risk Assessment Bureau (ESRAB). Table 1 presents the first batch of chemical to be analyzed and a second batch of chemicals will be identified before the end of fiscal year 2015-2016. The resulting data will subsequently support the needed computational in vitro-to-in vivo extrapolation (IVIVE) methods which will then be used to estimate human equivalent doses. The data obtained from these pharmacokinetic evaluations will be used to facilitate the addition of a risk context to the high-throughput in vitro screening data. Estimated Value: The overall value of the requirement, including the cost of the professional services, equipment, miscellaneous costs, and any other costs which will be associated with the requirement is estimated at $85,000 in fiscal year 2015-16, with an option estimated at $55,000 in fiscal year 2016-17). The total estimated value of the requirement over 2 fiscal years is $140,000. Ownership of Intellectual Property: Canada will own the Intellectual Property. Security Requirement: There is no security requirement. Mandatory Requirements: M1. The bidder’s project team must have a team leader with PhD in a biomedical sciences field and analytical expert with a PhD relevant to the work described in the Statement of Work. M2. The bidder’s project leader must demonstrate that within the last 5 years, they have undertaken projects to measure drug metabolism pharmacokinetic parameters using of in vitro analysis. M3. The bidder must have at least 5 years of experience in conducting drug metabolism pharmacokinetics studies. M4. The bidder must have at least 5 years of experience employing high end analytical techniques to assess in vitro experiments. M5. The bidder must clearly outline the methods that will be employed to meet the technical requirements described in the Statement of Work. Proposed methods must be clearly described, consistent with the SOW’s requirements, and be sufficiently detailed so as to demonstrate the bidder’s overall competence, experience and grasp of the required services. Selection Methodology The contract will be awarded to the bidder with the highest technical score who stays within the budget of $85,000 for this fiscal year (FY2015-16) and $55,000 for the option year FY2016-17. The total budget for this requirement, including the option year, is $140,000. Enquiries regarding this Request for Proposals are to be submitted in writing to: Robert Merrick Contracting Authority E-mail: Robert.Merrick@hc-sc.gc.ca

Provision of Scientific Expertise for Coordination and Conduct of Human Health Risk Assessment, Scientific Peer Reviews and Consultations

Health Canada | Published May 14, 2015  -  Deadline June 23, 2015
cpvs

NOTICE OF PROPOSED PROCUREMENT (NPP) Solicitation #: 1000166241 Closing Date: June 23, 2015 Time: 2:00 PM EDT This requirement is for the department of Health Canada. Title: Provision of Scientific Expertise for Coordination and Conduct of Human Health Risk Assessment, Scientific Peer Reviews and Consultations Scope: The Safe Environment Directorate (SED) wishes to establish various Standing Offers on a range of risk assessment activities to support its mandated roles to protect the health of Canadians from hazards posed by chemical substances, including air and water contaminants, novel substances and contaminated sites through risk assessment and risk management. The main purpose of the standing offer is to obtain a list of qualified companies that have a broad range of expertise in the area of human health risk assessment and provide scientific services which may include gathering scientific data and/or literature for conducting a human health risk assessment, development of methodologies and tools for human health risk assessment, providing scientific expertise and training on human health risk assessments, conducting human health risk assessments (may include exposure assessment or hazard characterization), scientific peer review of assessment reports and consultations on scientific issues relating to the approach of conducting human health risk assessment of chemicals, air and water contaminants and novel substances in the environment. Estimated Value: The total estimated value of the Standing Offer Agreement resulting from this Request for Standing Offer shall not exceed $20M including all applicable taxes and optional years. It is estimated that Health Canada will spend approx. $5M (GST included) for one (1) year with three (3) one-year optional extensions to be exercised at Health Canada’s discretion. Ownership of Intellectual Property: The Intellectual Property arising from the performance of the work under any call-ups against the Standing Offer will vest with the Contractor, unless specified in the individual call-up.. Security Requirement: Security requirements will be determined in the individual call-ups. It is the Standing Offer holder’s responsibility to have the necessary security clearances described in any call-up. Bidder Information: Document Safeguarding Capability (DSC) This Capability is in addition to a supplier’s Designated Organization Screening (DSC) or in addition to a supplier’s Facility Site Clearance (FSC) - both of which entail the security screening of the organization's Company Security Officer and employees, and in certain cases, the Key Senior Officials. The DSC, in addition, assesses the physical security of the organization's facilities to ensure they meet the requirements for the safeguarding of government information (hardcopy or digital) and assets. A Document Safeguarding Capability issued by the Canadian Industrial Security Directorate will authorize the organization to possess and store PROTECTED or Classified information and assets at their facility. Mandatory Requirements: M1. Holds M.Sc or Ph.D in biology, toxicology, chemistry, epidemiology, statistics (or scientific field relevant to human health risk assessment); Or proof of certification as a Diplomate of the American Board of Toxicology (DABT). (NOTE: Toxicology experience could include such factors as research, testing, teaching, hazard assessment, safety evaluation, management, or clinical toxicology in animals or humans.) M2. A minimum of 5 years experience with human health risk assessment; M3. A minimum of 2 years experience in providing scientific/technical or regulatory advice to government agencies or private sector organizations. M4. Two references are to be provided and will be contacted in order to evaluate the Bidder’s skills. M5. Disclosure of any potential conflict of interest by the Bidder or any subcontracting party that might hinder the objectivity, impartiality, credibility and reliability of any of the party. Selection Methodology The five (5) highest-ranked proposal(s) per stream meeting ALL Mandatory Requirements and achieving the total minimum score required for ALL Point-Rated Requirements and representing the best value to the Branch shall be recommended for inclusion within the SOA. Highest Compliant Combined Rating of Technical Merit and Price: It is understood by the parties submitting proposals that, to qualify, bidders must meet all mandatory requirements as well as the minimum score identified for the point-rated criteria. The contract will be awarded based on a determination of best value taking into account both the technical merit of the proposals and the price evaluations. To arrive at an overall score achieved by a firm, a weighting has been established whereby technical merit will be valued at 70% of the bid and price at 30%. Enquiries regarding this Request for Standing Offer (RFSO) are to be submitted in writing to: Name of the Contracting Authority: Robert Merrick E-mail address: Robert.Merrick@hc-sc.gc.ca

Particulate Matter Component Risk Analysis and Concentration

Health Canada | Published September 21, 2016  -  Deadline June 10, 2016
cpvs

NOTICE OF PROPOSED PROCUREMENT (NPP)

Solicitation #: 1000184225 Closing Date: October 06, 2016 Time: 2 p.m. EDT

This requirement is for the department of Health Canada.

Title: Particulate Matter Component Risk Analysis and Concentration

Scope:

Ambient particulate matter (PM) refers to a range of varied substances from human and natural sources, which exist as liquid droplets or solids over a wide range of sizes. When these particles are suspended in the air, they form important components of air pollution. These particles are either emitted directly, from a wide range of sources, or are formed in the atmosphere from the chemical changes of gasses such as sulfur oxides, nitrogen oxides and volatile organic compounds.

A number of studies from epidemiology, toxicology and controlled-exposure experiments have reported the adverse health effects of PM (which vary from illnesses related to the heart or lungs, to early death) but fewer studies have been done to estimate the public health risk attributable to the individual components of PM, or to examine the way in which risk varies over the level of exposure (concentration-response (C-R) shape) for PM mass or components. New methods have recently been developed to flexibly characterize the C-R shape between air pollution and health outcomes for long-term (chronic) exposure, but these have not been applied to short-term (acute) exposure.

The primary goal of the project will be to investigate the adverse health risk attributable to components of PM2.5, and to examine the shape of the concentration-response (C-R) function for PM2.5 and its components. To achieve this goal, the study has been broken into three overlapping phases. The first phase (2016-2017) will focus on the collection, validation and interpolation of reliable data for PM2.5 mass and its components. The second phase (2017-2018) will focus on statistical models and methods for estimation of annual adverse health risks due to PM2.5 and its components, beginning with mortality and proceeding to morbidity. The third phase (2018-2019) will extend these risks into estimation of the PM2.5 concentration-response curve, both locally for cities, and nationally for the Canadian population if the number of cities is not too small for statistical power of risk estimates. The first phase is considered below.

Objectives of the Requirement

This work is supposed to provide information on the following questions:

(1) What PM components have reasonable data availability for risk estimates in Canada? We need a list of PM components.

(2) What models have been developed PM components?

(3) Are there good models to be applied to Canada PM components? If so, what to be modified or improved?

a. One model would be good for all PM components in the list from (1)?

b. If not, what would be main factors to determine risk models?

(4) How to best model multiple PM component models?

(5) Any differences in model between mortality and morbidity?

(6) How best to deal with pre-2000 PM data?

(7) How best to model the interaction between temperature and PM components if exists?

Estimated Value:

The contract will be awarded to the bidder with the highest technical score within the budget of $60,000 for each fiscal year (one year contract with two option years, taxes not included).

Ownership of Intellectual Property:

The Contractor will own the Intellectual Property, while the Crown will have an irrevocable, royalty-free licence to use the IP.

Security Requirement:

There is no security requirement.

Mandatory Requirements:

M1. The bidder’s project leader must have a PhD from a recognized university with specialization in Statistics with experiences in Bayesian hierarchical models, Spectral analysis, and Smoother functions.

M2. The bidder’s project leader must demonstrate that within the last 5 years, they have undertaken at least three projects on Canadian population health for environmental issues.

M3.  The bidder’s project leader must have at least two peer-reviewed publications on Canadian population health in scientific journals listed in the Science Citation Index Expanded (within the last 5 years).

M4. The bidder’s project leader must show that they have experience working with Canadian environmental databases on fine particular matter (PM10 & PM2.5) and climate.

M5. The bidder’s project leader must have experience working with generalized additive model and/or generalized Poisson model.

M6. The bidder’s project leader must show that they have experience working with statistical software such as R.

Selection Methodology

The contract will be awarded to the bidder with the highest technical score within the budget of $60,000 for each fiscal year (one year contract with two option years, taxes not included).

Enquiries regarding this Request for Proposals are to be submitted in writing to:

Robert Merrick

Contracting Authority

E-mail:  Robert.Merrick@hc-sc.gc.ca