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Explore the mechanistic link between genome architecture, transcription and recombination in B cells

Department of Health and Human Services, National Institutes of Health | Published September 1, 2016  -  Deadline September 7, 2016
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(1) Action Code: Combined Synopsis/Solicitation (2) Date: September 1 (3) Year: 2016 (4) Contracting Office Zip Code: 20892 (5) Classification Code: Q301 (6) Contracting Office Address:6701 Rockledge DriveRockledge IIBethesda, MD 20892 (7) Subject/Title: Explore the mechanistic link between genome architecture, transcription and recombination in B cells. (8) Proposed Solicitation Number: HHSN26816AR00018S (9) Closing Response Date: September 7, 2016 (10) Contact Point: Kyle Wisor, Contract Specialist (11) Contract Award and Solicitation Number: TBD (12) Contract Award Dollar Amount: UKN (13) Contract Line Item Number(s): See 1449 (14) Contractor Award Date: UKN (15) Contractor Name: TBD (16) Description: The National Institutes of Health (NIH) is the nation's leading medical research agency, and the primary Federal agency conducting and supporting medical discoveries that improve people's health and save lives. The mission of the National Institute of Arthritis and Musculoskeletal and Skin Diseases is to support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases; the training of basic and clinical scientists to carry out this research; and the dissemination of information on research progress in these diseases. The goal of the Genomics and Immunity Section (GIS) is to unravel the molecular mechanisms driving early development and peripheral activation of B lymphocytes. In particular, the section is interested in the processes that assemble, diversify, and provide effector functions to antibody receptors, namely V(D)J recombination, somatic hypermutation, and class switching. Another major interest of the laboratory is to understand how deregulation of these reactions leads to B cell tumorigenesis. Related to the proposed project, both transcription and recombination of immunoglobulin genes are believed to be regulated by genome architecture. However there is still very little that is known about this topic simply because the techniques to explore architecture have just been developed in the last three years. (i) "This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued." (ii) The solicitation number is HHSN26816AR00018S and the solicitation is issued as a request for quote (RFQ). (iii) The solicitation document, the incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-89 effective 15 AUG 2016. (iv) The associated NAICS code is 541711, Research and Development in Biotechnology, and the small business size standard is 1000 Employees. The acquisition is being conducted in accordance with the procedures of FAR Part 12 and FAR Part 13. (v) The Contractor Requirements are listed below:(vi) The Contractor Shall Provide the following services: Tasks: To generate a comprehensive map of B cell architecture the GIS has established the following protocol: 1. The contractor shall isolate various mouse primary B cell samples: • The contractor shall enrich with magnetic beads different B cell populations, including resting naïve cells from the spleen. Cells will be processed untreated or they will be activated ex-vivo in the presence of mitogens (LSP) and cytokines (IL4). Furthermore, the intent is to process both cells isolated from WT mice or myc deficient ones, since in the absence of myc global transcription is compromised. B cell activation under conditions of ATP depletion or inhibition of histone deacetylation will also explore whether genome architecture requires energy or histone acetylation. 2. The contractor shall perform ten (10) runs, generating deep- sequencing HiC libraries. Perform the high-throughput sequencing using Illumina's X Ten machines from 20 samples provided by the GIS: • These state of the art machines can sequence up to 3 billion sequence reads per run. This is the range that is needed to uncover long-range chromatin interactions in any genome. Detailed HiC maps at his scale have only been produced a few times so far. With the new Illumina machines one can easily achieve the required output. 3. The contractor shall perform bioinformatic analysis: • Produce working maps of genome architecture the contractor's bioinformaticians will align the sequencing data to the mouse genome and transfer the files to NIAMS. Two dedicated bioinformaticians in NIAMS will perform all subsequent analyses to generate figures for the various papers. These last have been using R and other programing software, to write scripts that deal with the high-throughput nature of HiC libraries. Contractor Requirements: 1. The Contractor shall have access to an Illumina 10 X to perform the deep and high-throughput sequencing;2. Experience with the in situ HiC technique Government Requirements: 1. The GIS will isolate and activate B cells ex-vivo, from wild type and genetically modified mice. In addition, The GIS will study nuclear architecture in gene targeted CH12 B cell lines. Using CRISPR technology, the GIS has generated several point mutations at architectural factors. These mutants will help clarify how these proteins set up genome folding in mammalian cells; 2. Bioinformatic analysis: The GIS has two (2) dedicated bioinformaticians who will analyze the high-throughput data and help write the manuscripts. Deliverables: 1. The contractor will deliver HiC sequences within 3-4 months after contract award;2. Manuscript completion end of period of performance (vii) Period of Performance: Base Year: September 16, 2016 - September 15, 2017Option Period 1: September 16, 2017 - March 15, 2017 (viii) The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. (ix) The provision at FAR clause 52.212-2, Evaluation - Commercial Items, is applicable. The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation provides the most adventagous quote to the Government, technical factors considered. Technical Factors• Demonstrated experience with the in situ HiC Technique• Bioinformatician's experience with mapping of genome architecture(x) FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items, is applicable. An offeror shall complete only paragraphs (b) of this provision if the offeror has completed the annual representations and certificates electronically via http://www.acquisition.gov. If an offeror has not completed the annual representations and certifications electronically at the System for Award Management (SAM) website, the offeror shall complete only paragraphs (c) through (p) of this provision.(xi) FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. (xii) FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items, applies to this acquisition. Including the following clauses and Prohibitions: i. 52.222-3, Convict Labor ii. 52.222-21, Prohibition of Segregated Facilitiesiii. 52.222-26, Equal Opportunityiv. 52.222-36, Equal Opportunity for Workers with Disabilitiesv. 52.222-50 Combating Trafficking in Personsvi. 52.223-18, Encouraging Contractor Policies to Ban Text Messaging while Driving vii. 52.225-13, Restrictions on Certain Foreign Purchases (xiii) Additional Clauses: i. 52.2232-39, Unenforceability of Unauthorized Obligationsii. 52.227-14, Rights in Data - Generaliii. 52.217-8, Option to Extend Services--The Government may require continued performance of any services within the limits and at the rates specified in the contract. These rates may be adjusted only as a result of revisions to prevailing labor rates provided by the Secretary of Labor. The option provision may be exercised more than once, but the total extension of performance hereunder shall not exceed 6 months. The Contracting Officer may exercise the option by written notice to the Contractor within 30 days. (xiv) The Defense Priorities and Allocations System (DPAS) and assigned rating are not applicable. (xv) All responses must be received by September 7, 2016 at 9:00 AM EST and must reference number HHSN26816AR00018S. "Offers shall be submitted via the FedConnect web portal (www.fedconnect.net). For more questions please contact the Contract Specialist, Kyle Wisor, Phone: 301-402-3670. (17) Place of Contract Performance: National Institute of Health, NIAMS10 Center DriveBuilding 10Bethesda, MD 20892 (18) Set-aside Status: None Effective on or about March 1, 2016, The National Heart Lung and Blood Institute (NHLBI), Office of Acquisitions (OA) will begin using Compusearch's FedConnect as the communications web portal for all receipt of proposals, unless an exception applies as stated in the solicitation. Therefore potential offerors must be registered in FedConnect in order to submit proposals in response to future R&D, non-R&D Open Market procurements for the NHLBI and for which the NHLBI Consolidated Operations Acquisition Center (COAC) provides acquisition services. FedConnect is a web portal that connects agencies and vendors to streamline the process of doing business with the federal government. It also provides an open channel of communication with the government that is both secure and auditable. Vendors can register with FedConnect at https://www.fedconnect.net/FedConnect/default.htm. Please note that FedConnect is used by multiple federal agencies and therefore FedConnect assistance will be provided by Compusearch Software Systems, not the NHLBI OA. More information about registration requirements can be found by downloading the FedConnect Ready, Set, Go! Guide at https://www.fedconnect.net/fedconnect/Marketing/Documents/FedConnect_Ready_Set_Go.pdf. For assistance in registering or for other FedConnect technical questions please call the FedConnect Help Desk at (800) 899-6665 or email at support@fedconnect.net.    

Investigation of collagen architecture in breat biopsy tissues

Department of Health and Human Services, National Institutes of Health | Published March 2, 2015  -  Deadline March 17, 2015
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Short Title: Investigation of collagen architecture in breast biopsy tissues Document Type: Presolicitation Notice Solicitation Number: N02C052536-78 Posted Date: 3/2/2015 Response Date: 3/17/2015 Classification Code: Q301 NAICS Code: 541990 Contracting Office Address Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E140, Rockville, MD 20850, UNITED STATES Description National Cancer Institute (NCI), Division of Cancer Epidemiology and Genetics (DCEG), plans to procure on a sole source basis services to image previously reviewed and stained Hematoxylin and Eosin (H&E) slides using second-harmonic generation (SHG) microscopy and to quantify patterns of collagen alignment in these images in BREAST Stamp Project participants (n=154) from University of Wisconsin-Madison, 1111 Highland Ave Room 4533, Madison, WI 53705. This acquisition will be processed in accordance with simplified acquisition procedures as stated in FAR Part 13.106-1(b)(1). The North American Industry Classification System code is 541990 and the business size standard is $15.0 Million. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. The period of performance is twelve (12) months from date of award. It has been determined there are no opportunities to acquire green products or services for this procurement. Project background: Women with the highest levels of mammographic breast density are at 4-fold increased risk of breast cancer, compared with women who have the lowest levels of density. Mammographic density reflects the amount of fibroglandular tissue in the breast, which is composed of fibroblasts, epithelial cells and connective tissue. Increased collagen content is characteristic of dense tissue. Collagen remodeling has been linked to development and progression of breast cancer in animal models, and among women, specific tumor associated collagen signatures (TACS) have been linked to breast cancer and disease specific survival. However, links between mammographic density, TACS and pathologic diagnosis (benign vs. cancer) have not been explored in epidemiologic studies. Multiphoton second-harmonic generation (SHG) is a high-resolution microscopy technology that can image collagen fibers in live or fixed breast tissues, without special staining or labelling. These images can then be visually assessed for collagen (i.e., TACS) signatures and also assessed using a computer-assisted collagen curvelet transform fiber extraction algorithm (CT-FIRE), which enables automated quantitative analysis of collagen fiber length, angle and waviness from the SHG images of breast tissues. Using these methods, this study will test whether collagen fiber signatures or patterns of collagen features are related to mammographic breast density and pathologic diagnosis within NCI's Breast Radiology Evaluation And Study of Tissues (BREAST) Stamp Project. The BREAST Stamp Project was designed to investigate molecular mechanisms that mediate associations of elevated mammographic density with cancer by studying volumetric density and corresponding clinical biopsy tissues from women undergoing diagnostic image-guided breast biopsies. The novel mammographic density measures collected in this project include quantitative measurements of density in small regions surrounding suspicious targets prior to clinical biopsy. This study design will allow the association of quantitative measurements of volumetric density at the biopsy site with collagen signatures and pathologic diagnosis to be determined, to test the hypothesis that stromal alterations are related to breast cancer and high density. Contractor Requirements are: Image multiple sections of previously reviewed and stained Hematoxylin and Eosin H&E slides using the state-of-the-art SHG microscopy tool for benign (n=77) and malignant (n=77) breast tissues from participants in the BREAST Stamp Project. Following imaging, assess collagen architectural patterns using visual assessment for each study participant and assign each participant with a ‘Tumor Associated Collagen Signature' Score. Following imaging, apply the algorithm CT-FIRE to quantitatively assess collagen architectural patterns, including collagen fiber length, angle and waviness. Implement quality control (QC) measures for image processing and analysis and for collagen assessment analysis and to provide QC results. Provide results including representative images, collagen TACS signatures, collagen fiber length, angle and waviness for these breast tissues from each study participant. To return H&E analyzed slides to NCI upon completion of analysis. Government Responsibilities The NCI COR shall provide the Contractor with microscopic slides containing breast biopsy tissues previously stained for H&E from 154 BREAST Stamp Projects participants. The NCI COTR shall review the data following completion of the task. Reporting Requirements and Deliverables Deliverables: The contractor will provide receipt of all the slides that are shipped. The Contractor will provide electronic data and analytic results outlined above. Electronic data may be submitted using Excel spreadsheets. The Contractor will return the H&E stained breast biopsy tissue slides to NCI following completion of the analysis in light protected boxes at room temperature. This notice is not a request for competitive quotation. However, if any interested party, especially small business believes it can meet the above requirement, it may submit a proposal or quote for the Government to consider. The response and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Responses must be received in the contracting office by 1 PM EST, on March 17, 2015. All responses and questions must be via email to Francisco Mendoza, Contracting Specialist at francisco.mendoza@nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must be registered and have valid certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA) through sam.gov. Reference: N02C052536-78 on all correspondence.

Architectural and Engineering Liaison

Department of Health and Human Services, National Institutes of Health | Published August 17, 2015  -  Deadline August 24, 2015
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Architectural and Engineering Liaison HHS-NIH-NIDA-SSSA-PSOL-15-767 INTRODUCTION This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. This acquisition is being conducted in accordance with the procedures of FAR Part 13--Simplified Acquisition Procedures and FAR Part 12--Acquisition of Commercial Items. The solicitation number is HHS-NIH-NIDA-(SSSA)-PSOL-15-767 and the solicitation is issued as a PRE-SOLICITATION, NOTICE OF INTENT, to award a contract on a noncompetitive basis to Maris Solutions, 14820 Bauer Drive, Rockville, MD 20853, DUNS: 079379907. REGULATORY & STATUTORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13--Simplified Acquisition Procedures, FAR Part 12--Acquisition of Commercial Items, and Subpart 6.302-1, Only one responsible source and no other supplies or services will satisfy agency requirements, and is expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13--Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6--Competition Requirements. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-83 effective August 4, 2015. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The associated NAICS code for this requirement is 541611 and the small business size standard is $15.0 million. CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION DETERMINATION The non-competitive determination is based upon the market research conducted as prescribed in FAR Part 10--Market Research, specifically the results of market research concluded that there was only one response to the combined synopsis solicitation, number HHS-NIH-NIDA-(SSSA)-15-377, which was posted on FBO on June 11, 2015 and closed on July 10, 2015. In order to revise the requirement to increase competition a four month award with two one month options is being considered; this will avoid a disruption of key services while the solicitation's scope is being changed and the requirement is being re-competed. This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. DESCRIPTION OF REQUIREMENT Background The National Institute of Neurological Disorders and Stroke (NINDS) is a part of the National Institutes of Health (NIH), conducting research into the causes, treatment, and prevention of neurological disorders and stroke. The NINDS mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. Purpose and Objectives The objective is to acquire a liaison to provide architectural and engineering administrative and managerial support services to facilitate renovation projects for NINDS. Project Description The individual shall work as a liaison between NINDS leadership, operations staff, Principal Investigators (PIs), construction personnel, the scientific community and other relevant stakeholders. The liaison will serve as an intermediary between the aforementioned parties as they analyze project requirements, discuss plans, formulate alternate solutions and implement decisions. Delivery/Period of Performance The anticipated period of performance is as follows: Base: 09/01/2015 to 12/31/2015 Option Month 1: 01/01/2016 to 01/31/2016 Option Month 2: 02/01/2016 to 02/28/2016 Contract Type A firm fixed price purchase order with NET30 invoicing terms is anticipated. RESPONSE INSTRUCTIONS Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; and maintenance availability. APPLICABLE TERMS AND CONDITIONS The following FAR clauses and provisions shall apply to this solicitation: 1. All Offerors MUST be actively registered in the System for Award Management (SAM) www.sam.gov. 2. The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items (April 2014), applies to this acquisition. 3. FAR clause 52.212-2, Evaluation - Commercial Items (October 2014) applies to this acquisition. (a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate offers: FACTOR Experience of personnel • The resumes of proposed key personnel will be evaluated for documented experience with serving as a liaison for multiple projects simultaneously, presenting and collaborating with a minimum of four different departments, knowledge of construction including but not limited to swing spaces and renovation projects, and possessing scientific knowledge of a biomedical investigative community and live specimen environments in order to effectively communicate the goals of scientists in such environments. • The proposal must demonstrate, with examples, the quality and depth of education and experience, the appropriate certifications and technical qualifications of key personnel and the applicability of that experience. Similar projects must convey similarity in topic, dollar value, workload, duration, and organizational environment complexity. Understanding the project • Offerors will be evaluated on their ability to present a rational approach to the challenges that are specific to this contract given the unique concerns of scientists, construction, budget, and administrative departments. Corporate Experience/Past Performance • Offerors must demonstrate their corporate qualifications for performing the tasks under this requirement. • Previous experience of the offeror in managing similar or related contracts of comparable size and complexity will be evaluated. Cost The Offeror(s) cost/price proposal will be evaluated for reasonableness and best value to the government. For a price to be reasonable, it must represent a price to the government that a prudent person would pay when consideration is given to prices in the market. The Government intends to make an award(s) to that offeror whose proposal provides the best overall value to the Government. Technical and past performance, when combined, are significantly more important, when compared to price. (b) Options. The Government will evaluate offers for award purposes by adding the total price for all options to the total price for the basic requirement. The Government may determine that an offer is unacceptable if the option prices are significantly unbalanced. Evaluation of options shall not obligate the Government to exercise the option(s). (c) A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer's specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award. 4. A completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items (March 2015), is required with any offer submitted. This requirement may be met by completion of the provision in the System for Award Management. 5. FAR clauses 52.212-4, Contract Terms and Conditions - Commercial Items (May 2015) and 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items (May 2015) apply to this acquisition. 6. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. In addition, the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." CLOSING STATEMENT All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency. All responses must be received by August 24, 2015 at 8:00 am, Eastern Standard Time (EST) and must reference solicitation number HHS-NIH-NIDA-SSSA-PSOL-15-767. Responses may be submitted electronically to andriani.buck@nih.gov or by U.S. mail to the National Institute of Drug Abuse (NIDA), Station Support / Simplified Acquisition Branch (SS/SA), 31 Center Drive, Building 31, Room 1B59, Bethesda, Maryland 20892-2080, Attention: Andriani Buck. Fax responses will be accepted at (301) 480-1358. For information regarding this solicitation, contact Andriani Buck by email at andriani.buck@nih.gov.

Architectural and Engineering Liaison

Department of Health and Human Services, National Institutes of Health | Published June 11, 2015  -  Deadline July 10, 2015
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COMBINED SYNOPSIS / SOLICITATION This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The solicitation number is HHS-NIH-NIDA-(SSSA)-15-377 and the solicitation is issued as a request for proposal (RFP). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5-Test Program for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is expected to exceed the simplified acquisition threshold. The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2005-82 effective May 7, 2015. This acquisition is set aside 100% for small businesses. The associated NAICS code 541611 and the small business size standard $15.0. STATEMENT OF OBJECTIVES The objective is to acquire a liaison to provide architectural and engineering administrative and managerial support services to facilitate renovation projects for NINDS. Title: Architectural and Engineering Liaison The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life and reduce illness and disability. The National Institutes of Health is comprised of 27 Institutes and Centers. The National Institute of Neurological Disorders and Stroke (NINDS), is one of those member institutes. The NINDS' mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. NINDS DIR seeks an independent contractor to provide day-to-day, on-site liaison services of an architectural and engineering nature to satisfy the overall operational objectives of the National Institute of Neurological Disorders and Stroke. It is anticipated that the number of spaces requiring Architectural and Engineering support and therefore requiring attention from the liaison will increase during the duration of this agreement. The individual shall work as a liaison between NINDS leadership, operations staff, Principal Investigators (PIs), construction personnel, the scientific community and other relevant stakeholders to serve as an intermediary between the aforementioned parties as they analyze project requirements, discuss plans, formulate alternate solutions and implement the finalized plan to provide services and deliverables through to successful project completion. Scope of Work The contractor shall: 1. Serve as a liaison between leadership, construction and scientific communities for multiple projects simultaneously. 2. Serve as a point of contact between the Scientific Director, EO offices, NINDS investigators, and NIH facility management. 3. Prepare and present planning and status reports for project officer approval. 4. Collaborate with leadership, construction, scientists, and financial personnel to ensure funding and timeline goals are met. 5. Possess the knowledge to work in biomedical investigative and active Continuity of Operations (COOP) environments. 6. Possess experience assisting in successfully relocating individuals and groups of 1 - 500 people and their technical environments, labs, utilities, furniture, etc. 7. Possess an understanding of planning swing spaces. 8. Shall have experience presenting plans and obtaining buy-in from leadership, construction, finance and scientific communities. 9. Possess an Occupational Safety Hazard Administration (OSHA) Certificate 10. Shall have strong organizational, interpersonal and time / management skills. Key Personnel Requirements Certifications required of the candidate: 1. Certified Professional Engineer (PE) 2. Certified Construction Manager (CCM) 3. LEED Accredited Professional (AP+BD+C) Key personnel proposed for the current position must possess: 1. Either a Bachelor's degree in an Engineering specialty related to construction; Or a Bachelor's degree and 4 years' experience with HVAC, electrical, utilities, etc; 2. AND 8+ years' Federal Government construction/renovation experience; 3. AND 5+ years' experience in laboratory projects; Qualifications should be easily identifiable in a resume or a clearly delineated section of the proposal. Period of Performance Base Year: September 1, 2015 - August 31, 2016 Option Year 1: September 1, 2016 - August 31, 2017 Option Year 2: September 1, 2017 - August 31, 2018 Option Year 3: September 1, 2018 - August 31, 2019 Option Year 4: September 1, 2019 - August 31, 2020 Please refer to the attached Statement of Work for further detail, specifications, and evaluation criteria. FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. Offerors must include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items, with its offer. FAR clause 52.212.-2, Evaluation - Commercial Items, is applicable to this requirement. Offers will be evaluated on: Item # Technical Requirements Score Points 1 Demonstrate ability to consult with leadership, construction and scientific communities regarding multi-function collaboration to accomplish Investigative Spaces from concept to fruition. Demonstrate ability to understand and be able to accurately communicate technical, construction, budget/ finance, new tenure track hire and NINDS leadership data and points of view, present and advance tradeoffs in manner that facilitates concurrence from all parties. 10 2 Demonstrate ability to simultaneously serve as a liaison for 15-20 projects at the same time meeting the objectives of each. 10 3 Demonstrate ability to act as point of contact among Scientific Director (SD) and EO offices, NINDS investigators, and NIH facility management. 10 4 Demonstrate ability to collect data, generate detailed status and planning reports for project officer approval, and present reports to top to mid-management leadership, to construction teams, and to investigative and experimenting scientists. 5 5 Demonstrate ability to collaborate and coordinate among leadership, construction, scientific and budget/finance communities to ensure efficient use of funding and to adhere to schedule for new and renovation projects. 5 6 Demonstrate sufficient knowledge of shaping a biomedical investigative environment containing HVAC, nitrogen(N2), carbogen (CO2O2), carbon dioxide (CO2) [lab vacuum, lab gases, lab air], bio-hazard storage, freezer farms, fume hoods, bio-safety cabinets, air tables, centrifuges and vivariums so that concerns from different parties regarding biomedical investigative environments can be addressed , detailed, and properly relayed to the appropriate parties. 10 7 Demonstrate experience operating in an active Continuity of Operations (COOP) environment containing live research specimen since liaison services in such an environment may be necessary and knowledge of the environment will be necessary to serve as an effective intermediary in such situations. Please see http://www.ors.od.nih.gov/ser/depc/Pages/coop.aspx for more detailed information. 10 8 Provide evidence of the ability to ensure that renovation projects proceed on schedule and on budget, to inform SD and EO or equivalent offices of possible deviations from schedule and budget, and to collaborate with staff to find solutions that may arise thereby keeping projects on schedule and within budget. 8 9 Demonstrates familiarity with and ability to work with NINDS' Continuity of Operations (COOP)/Emergency personnel and team responders in the event of building emergencies by giving specific experience of employing protocols working with emergency personnel and team responders. 8 10 Evidence of strong communication skills: oral, written, and in presenting material to a group. 10 11a. Display an ability to collaborate with the appropriate parties in the oversight and implementation of a chlorination system for animal vivarium which houses an average of 12,000 mouse/rat cages. Currently, the water system is contaminated, research is affected and behavioral studies are also affected; the ability to serve as an intermediary in order to help resolve these and/or similar challenges should be detailed. 5 11b. Display an ability to collaborate with the appropriate parties in the oversight of the study and renovation of an animal quarantine area including the assessment of HVAC and installation of ducted biosafety cabinets. 3 11c. Display an ability to serve as a liaison with the parties involved with the renovation of specifically designed animal holding areas that must be continued for virus-infected rodents. 6 Technical Score: 100 KEY PERSONNEL REQUIREMENTS Key personnel proposed for the current position must possess: 1 Either a Bachelor's degree in an Engineering specialty related to construction; Or a Bachelor's degree and 4 years' experience with HVAC, electrical, utilities, etc; Pass/Fail 2 AND 8+ years' Federal Government construction/renovation experience; Pass/Fail 3 AND 5+ years' experience in laboratory projects; Pass/Fail Certifications required of the candidate: 1 Certified Professional Engineer (PE) Pass/Fail 2 Certified Construction Manager (CCM) Pass/Fail 3 LEED Accredited Professional (AP+BD+C) Pass/Fail The evaluation will be based on the evaluation of the proposal in relation to the scope of work and the evaluation criteria. Paramount consideration shall be given to the evaluation of technical factors. Although technical factors are of paramount consideration in the award, cost or price is also important to the overall task order award decision. All evaluation factors other than cost or price, when combined, are significantly more important than cost or price. However, cost or price may become a critical factor in source selection in the event two or more offers are determined to be essentially equal following the evaluation of all factors other than cost or price. Cost-price will be evaluated for reasonableness in relation to the requirements of the contract. In addition, a final best-buy analysis will be performed taking into consideration the results of the technical evaluation, cost-price analysis, and the offeror's ability to complete the work within the Government's required schedule. An award will be made to the offeror whose proposal conforms to the requirements of the scope of work and is most advantageous to the Government with technical merit, cost-price, and other factors considered. The Government reserves the right to reject any or all offers or any part thereof and to waive any minor informality or irregularity in offers received. FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All responses must be received by July 10, 2015, 8:00 am EST and must reference number HHS-NIH-NIDA-(SSSA)-15-177. Responses must be submitted electronically to andriani.buck@nih.gov and by U.S. mail to the National Institute of Drug Abuse (NIDA), Station Support / Simplified Acquisition Branch (SS/SA), 31 Center Drive, Building 31, Room 1B59, Bethesda, Maryland 20892-2080, Attention: Andriani Buck. Fax responses will not be accepted. The hard copy documents must comply with FAR 52.204-4 -- Printed or Copied Double-Sided on Postconsumer Fiber Content Paper. Printed or Copied Double-Sided on Postconsumer Fiber Content Paper (May 2011) (a) Definitions. As used in this clause- Postconsumer fiber means- (1) Paper, paperboard, and fibrous materials from retail stores, office buildings, homes, and so forth, after they have passed through their end-usage as a consumer item, including: used corrugated boxes; old newspapers; old magazines; mixed waste paper; tabulating cards; and used cordage; or (2) All paper, paperboard, and fibrous materials that enter and are collected from municipal solid waste; but not (3) Fiber derived from printers' over-runs, converters' scrap, and over-issue publications. (b) The Contractor is required to submit paper documents, such as offers, letters, or reports that are printed or copied double-sided on paper containing at least 30 percent postconsumer fiber, whenever practicable, when not using electronic commerce methods to submit information or data to the Government. (End of Clause) The technical proposal excluding all cover pages, table of contents, resumes and cost proposals must be limited to twenty five (25) pages in length. The font for both the technical and cost proposal must be either 11 or 12 point Arial or Times New Roman. Contact Andriani Buck at andriani.buck@nih.gov for information regarding the solicitation. Questions should be limited to five (5) per vendor and be submitted by June 22nd, 2015. Responses to questions for clarification will be posted as a modification to this solicitation.

NINDS architectural and engineering administrative and managerial support

Department of Health and Human Services, National Institutes of Health | Published February 23, 2016  -  Deadline May 16, 2016
cpvs

This is a solicitation for commercial services prepared in accordance with the format in Subpart 12.2, as supplemented with additional information included in this notice. This announcement constitutes the only written solicitation; proposals are being requested and a separate solicitation will not be issued. The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2005-87 effective April 6, 2016. This acquisition will be processed under FAR Part 12, Simplified Acquisition Procedures (SAP), Acquisition of Commercial Items, and is set aside 100% for small businesses. The Solicitation Number for this acquisition is HHS-NIH-NIDA-SSSA-RFP-16-47 and is being issued as a Request for Proposal (RFP). The North American Industry Classification System (NAICS) Code for this procurement is 541611 and the Small Business Size Standard is $15.0 million dollars. BACKGROUND The National Institute of Neurological Disorders and Stroke (NINDS) DIR seeks an independent contractor to provide day-to-day, on-site liaison services of an architectural and engineering nature to satisfy the overall operational objectives of the National Institute of Neurological Disorders and Stroke. It is anticipated that the number of spaces requiring Architectural and Engineering support and therefore requiring attention from the liaison will increase during the duration of this agreement. STATEMENT OF OBJECTIVES The objective is to acquire a liaison to provide architectural and engineering administrative and managerial support services to facilitate renovation projects for NINDS. STATEMENT OF WORK The individual shall work as a liaison between NINDS leadership, operations staff, Principal Investigators (PIs), construction personnel, the scientific community and other relevant stakeholders to serve as an intermediary between the aforementioned parties as they analyze project requirements, discuss plans, formulate alternate solutions and implement the finalized plan to provide services and deliverables through to successful project completion. The liaison shall: 1. Serve as a liaison between the Scientific Director, EO offices, NINDS investigators, and NIH facility management regarding multi-function collaboration to accomplish Investigative Spaces from concept to fruition for approximately 15-20 projects simultaneously.2. Collaborate and coordinate among leadership, construction, scientific and budget/finance communities to ensure efficient use of funding and to adhere to schedule for new and renovation projects, to inform SD and EO or equivalent offices of possible deviations from schedule and budget, and to collaborate with staff to find solutions that may arise thereby keeping projects on schedule and within budget. 3. Possess experience assisting in successfully relocating individuals and groups of 1 - 500 people and their technical environments, labs, utilities, furniture, etc. 4. Possess an understanding of planning swing spaces. 5. Possess an Occupational Safety Health Administration (OSHA) Certificate KEY PERSONNEL Resumes are required for all personnel proposed. The contractor shall propose at least one key person that meets all the requirements of this Statement of Work. Please list Key Personnel below in order of importance, their duty location, primary phone number, alternate phone number, email and an alternate Lead POC and their data in case of emergencies. 1. Name and Title, Lead POC:Duty address:Primary phone:Alt. Phone:Email:Alternate Lead POC: 2. Name and Title, Alternate Lead POC:Duty address:Primary phone:Alt. Phone:Email:Alternate Lead POC: 3. Name and Title Duty address: On-Site Primary phone: Alt. Phone: Email: Sole proprietors should find a suitable replacement in case the lead POC is unable to continue services. Teaming agreements or other agreements with the replacement should be included with the proposal. The replacement's credentials should meet the requirements detailed in this Statement of Work. OFFERORS SHOULD ASSURE THAT ALL PERSONNEL PROPOSED SHALL NOT BE COMMITTED ON FEDERAL GRANTS AND CONTRACTS FOR MORE THAN A TOTAL OF 100% OF THEIR TIME. IF THE SITUATION ARISES WHERE IT IS DETERMINED THAT A PROPOSED KEY PERSONNEL IS COMMITTED FOR MORE THAN 100% OF HIS OR HER TIME, THE GOVERNMENT WILL REQUIRE ACTION ON THE PART OF THE OFFEROR TO CORRECT THE TIME COMMITMENT. The key personnel specified in this contract are considered to be essential to work performance. At least 30 days prior to diverting any of the specified individuals to other programs or contracts (or as soon as possible, if an individual must be replaced, for example, as a result of leaving the employ of the Contractor), the Contractor shall notify the Contracting Officer and shall submit comprehensive justification for the diversion or replacement request (including proposed substitutions for key personnel) to permit evaluation by the Government of the impact on performance under this contract. The Contractor shall not divert or otherwise replace any key personnel without the written consent of the Contracting Officer. The Government may modify the contract to add or delete key personnel at the request of the Contractor or Government. NIH TRAINING Additional NIH mandated training, such as JCAHO training, will be necessary and if not already completed must be after award. If the individual has completed the NIH JCAHO training the name, date of attendance, and any other evidence of training completion should be provided. DELIVERABLES All reports required herein shall be submitted in electronic format. All paper/hardcopy documents/reports submitted under this contract shall be printed or copied, double-sided, on at least 30 percent post consumer fiber paper, whenever practicable, in accordance with FAR 4.302(b). Technical Progress Reports 1. In addition to the required reports set forth elsewhere in this Schedule, the preparation and submission of regularly recurring Technical Progress Reports will be required in any contract resulting from this solicitation. These reports will require descriptive information about the activities undertaken during the reporting period and will require information about planned activities for future reporting periods. The frequency and specific content of these reports will be determined prior to contract award. [ ] Monthly[ ] Quarterly[ ] Semi-Annually[X] Annually[ ] Annually (with a requirement for a Draft Annual Report)[X] Final - Upon final completion of the contract[ ] Final - Upon final completion of the contract (with a requirement for a Draft Final Report) 2. Summary of Salient Results The Contractor will be required to prepare and submit, with the final report, a summary (not to exceed 200 words) of salient results achieved during the performance of the contract. This report will be required on or before the expiration date of the contract. Other Reports/Deliverables Monthly (unless otherwise stated), the contractor shall provide documentation evidence of any and/or all work products, including, but not limited to, the following tasks: • Weekly meetings with Assistant Director for Science Administration, NINDS to provide status updates on all ongoing projects, plans, collaborations, renovations, proposed equipment purchases, space allocations, movement of NINDS staff, etc.• Bi-weekly meeting with the Scientific Director, NINDS to provide updates on the areas as listed in the first deliverable.• Basic deliverables as are typical in an office environment (including but not limited to work products, spreadsheets, database logs, and other documents related to plans, projects, evaluations, meeting presentations)• Computer generated work, including spreadsheet and database logs, to ensure all areas of construction, renovation, movement of staff and equipment, and other duties are processed in a timely manner. • Records maintained on budget for renovations to ensure funding availability. As requested, provide raw data to support status of dashboard funding reports. The raw data will be the property of NINDS.• Other reports as called out in this document or as required during the course of performance including but not limited to emergency status reports which will be delivered on an as-needed or immediate basis.• Semiannual performance reports. PLACE OF PERFORMANCE National Institute of Neurological Disorders and StrokeDivision of Intramural Research Programs9000 Rockville Pike35 Convent DriveBuilding 35, Room GF352Bethesda, MD 20892 This work may also be performed via Telework when the Government closes offices as announced by the Office of Personnel Management (OPM). PERIOD OF PERFORMANCE Base Year: July 1, 2016 - June 30, 2017Option Year 1: July 1, 2017 - June 30, 2018Option Year 2: July 1, 2018 - June 30, 2019Option Year 3: July 1, 2019 - June 30, 2020Option Year 4: July 1, 2020 - June 30, 2021 OPERATIONAL HOURS Work will be performed 40 hours per week during normal business hours 8:00 am until 5:00 pm, Monday-Friday, excluding ten (10) Federal holidays. However, there might be instances in which more than 40 hours a week are required and/or work outside of normal business hours may need to be performed. LEVEL OF EFFORT The Government's requirement for the work set forth in the Statement of Work of this solicitation is 1,920 direct labor hours. It is estimated that the labor hours are constituted as specified below and will be expended approximately as follows:Labor HoursYear 1 Year 2 Year 3 Year 4 Year 51,920 1,920 1,920 1,920 1,920 PAGE AND FORMATTING LIMITATIONS The Technical Proposal shall not exceed 50 single-sided pages or 25 double-sided pages. This page limitation does not include the cover sheet, abstract, table of contents, personnel, facilities, equipment and resources, other considerations, schedule, other support, and cost information. Appendices shall not exceed a total of 30 single-sided pages or 15 double-sided pages. Pages in excess of the limitation will be deleted and will be neither read nor evaluated. Each page of the technical proposal must be numbered sequentially. Offerors are encouraged to limit the overall size of the technical proposal, inclusive of appendices, attachments, etc. Type density and size must be 10 to 12 points. If constant spacing is used, 15 cpi (characters per inch) or fewer shall be used, whereas proportional spacing should provide an average of no more than 15 cpi. There must be no more than six lines of text within a vertical inch. Margins must be no less than ½ inch around, exclusive of headers and footers. The proposal must be signed by an official authorized to bind your organization and must stipulate that it is predicated upon all the terms and conditions of this RFP. One original and three (3) copies of your proposal shall be submitted to: National Institutes of HealthNational Institute on Drug AbuseStation Support Simplified Acquisition BranchAndriani Buck, Contract Specialist31 Center Drive, Suite 1B59Bethesda, MD 20892-7511. Proposals will be typewritten, paginated, reproduced on letter size paper, printed/copied double-sided, on at least 30 percent post consumer fiber paper, as required by FAR 4.302(b), and will be legible in all required copies. To expedite the proposal evaluation, all documents required for responding to the RFQ should be placed in the following order: I. COVER PAGEInclude RFP title, number, name of organization, DUNS No., identification of the proposal part, and indicate whether the proposal is an original or a copy. The solicitation number HHS-NIH-NIDA-SSSA-RFP-16-47 must be referenced on the cover page. II. TECHNICAL PROPOSALIt is recommended that the technical proposal consist of a cover page, a table of contents, and the information requested in the Technical Proposal Instructions and as specified in SECTION J, List of Attachments. Offers will be valid for 120 days unless a different period is specified by the offeror. MANDATORY EVALUATION FACTORS MANDATORY QUALIFICATION CRITERIA Listed below are mandatory qualification criteria. THE OFFEROR SHALL INCLUDE ALL INFORMATION WHICH DOCUMENTS AND/OR SUPPORTS THE QUALIFICATION CRITERIA IN ONE CLEARLY MARKED SECTION OF ITS TECHNICAL PROPOSAL. The qualification criteria establish conditions that must be met at the time of receipt of Technical Proposals by the Contracting Officer in order for your proposal to be considered any further for award. The following items have been determined to be essential for this requirement and in being able to complete the tasks associated with this requirement;a. Either a Bachelor's degree in an engineering specialty or a Bachelor's degree and four (4) years' experience with HVAC, Electrical, and commercial Utilities.b. Minimum of five (5) years' experience of Federal Government construction/renovation(s).c. Minimum of five (5) years' experience of in scientific\research projects.d. Professional Engineer (PE) certification.e. Construction Manager (CM) certification TECHNICAL EVALUATION ELEMENTS The evaluation factors are used by the technical evaluation committee when reviewing the technical proposals. Offerors proposals will be evaluated on the demonstrated experience and understanding of the project in relation to the specifications outlined in the solicitation and the statement of work.The acceptability of the technical portion of each contract proposal will be evaluated by a technical review committee. The committee will evaluate each proposal in strict conformity with the evaluation factors of the RFP, utilizing point scores and written critiques. The committee may suggest that the Contracting Officer request clarifying information from an offeror. The Government reserves the right to award a contract without discussions if the Contracting Officer determines that the initial prices are fair and reasonable and that discussions are not necessary. If award will be made without conducting discussions, offerors may be given the opportunity to clarify certain aspects of their proposal (e.g., the relevance of an offeror's past performance information and adverse past performance information to which the offeror has not previously had an opportunity to respond) or to resolve minor or clerical errors. The process described in FAR 15.101-1 will be employed, which permits the Government to make tradeoffs among cost or price and non-cost factors and to consider award to other than the lowest price offeror or other than the highest technically rated offeror. The NIDA reserves the right to make a single award, multiple awards, or no award at all to the RFP. In addition, the RFP may be amended or canceled as necessary to meet the NIDA requirements. The factors and sub factors below are listed in the order of relative importance with weights assigned to the factors for evaluation purposes.Technical ExperienceDemonstrated corporate and\or key personnel experience in the following: 70 pointsa. Knowledge of shaping (designing a layout) a biomedical investigative environment that will contain lab gases (for example nitrogen (N2), carbogen (CO2O2, carbon dioxide (CO2)). Lab vacuum system(s), lab equipment (e.g. bio safety cabinets, fume hoods centrifuges, etc.) that conforms to multiple users.b. Management Liaison - Communicating construction concerns, finance\budgets and tradeoffs obtained from senior lab management and relay information to facility managers, architects, construction project managers and obtain buy in from all parties.c. Collecting data and generating detailed status reports to project team that includes senior management, construction personnel, facilities management and scientific personnel.d. Ability to work in an environment containing live research specimene. Ability to work within a Continuity of Operations (COOP)/Emergency personnel and team response: PLEASE SEE HTTP://WWW.ORS.OD.NIH.GOV/SER/DEPC/PAGES/COOP.ASPX FOR DETAILED INFORMATION ON A COOP ENVIRONMENT.f. Ability to collaborate appropriate parties in the oversight and implementation of a water system for vivarium housing of equal or greater capacity (12,000 mice and\or rat cages).g. Ability to collaborate appropriate parties in the oversight of the development and renovation of an animal quarantine area. NOTE: OFFERORS PROPOSALS MUST INCLUDE EXAMPLES OF CORPORATE AND\OR KEY PERSONNEL EXPERIENCE FOR EACH OF THE ABOVE SUB-FACTORS, FAILURE TO PROVIDE DETAILED EXAMPLES WILL RESULT IN A DETERMINATION OF NON RESPONSIVE FOR THE PARTICULAR SUB FACTOR(S).Understanding of Requirement 15 pointsOfferors must demonstrate their understanding of the technical objectives and tasks of this requirement described herein and in all the attachments. Past Performance\Corporate Experience 15 points Offerors must provide at least two (2) past contracts of equal size or complexity, the information must contain the name of the company or individual contracted with, address, phone number and email address. The Government will evaluate the Offerors on past performance based on the information provided in the proposal and the Government reserves the right to contact the parties provided as references in the Offerors proposal. In addition the Government may evaluate the Offeror based on information obtained from other sources known to the Government as to past performance of the Offeror. PAST PERFORMANCE FACTOR The Government may evaluate the offeror's past performance based on information obtained from references provided by the offeror, other relevant past performance information obtained from other sources known to the Government, and any information supplied by the offeror concerning problems encountered on the identified contracts and corrective action taken. The Government will assess the relative risks associated with each offeror. Performance risks are those associated with an offeror's likelihood of success in performing the acquisition requirements as indicated by that offeror's record of past performance. The Government will consider the currency and relevance of the information, source of the information, context of the data, and general trends in the offeror's performance. The lack of relevant a performance record may result in an unknown performance risk assessment, which will neither be used to the advantage nor disadvantage of the offeror. AWARD CRITERIAThe major evaluation factors for this solicitation include technical (which encompasses experience and past performance factors) and cost/price factors. Although technical factors are of paramount consideration in the award of the contract, cost/price is also important to the overall contract award decision. All evaluation factors other than cost or price, when combined, are significantly more important than cost/price. The Government intends to make an award(s) to that offeror whose proposal provides the best overall value to the Government. The evaluation will be based on the demonstrated capabilities of the prospective Contractors in relation to the needs of the project as set forth in the RFP. The merits of each proposal will be evaluated carefully. Each proposal must document the feasibility of successful implementation of the requirements of the RFP. Offerors must submit information sufficient to evaluate their proposals based on the detailed factors listed above. Offeror(s) cost/price proposal will be evaluated for reasonableness. For a price to be reasonable, it must represent a price to the government that a prudent person would pay when consideration is given to prices in the market. Normally, price reasonableness is established through adequate price competition, but may also be determined through cost and price analysis techniques as described in FAR 15.404. PROVISIONS AND CLAUSES It is contemplated that a level of effort fixed price type contract will be awarded. Any resultant contract shall include the clauses applicable to the selected offeror's organization and type of contract awarded as required by Public Law, Executive Order, or acquisition regulations in effect at the time of execution of the proposed contract. The following Provisions and Clauses apply: FAR 52.212-1 Instruction to Offerors-/Commercial Items (OCT 2015); FAR 52.212-2 Evaluation - Commercial Items (OCT 2014) (Additional Evaluation criteria set forth in the solicitation); FAR 212-3, Offeror Representations and Certifications - Commercial Items (NOV 2015); FAR 52.212-4 Contract Terms and Conditions Commercial Items (MAY 2015); FAR 52.217-8 Option To Extend Services (NOV 1999); FAR 52.217-9 Option to Extend the Term of the Contract, (MAR 2000); FAR 219-6 Notice of Total Small Business Set-Aside (NOV 2011); FAR 52.222-3 Convict Labor (JUN 2003); FAR 52.223-6 Drug Free Workplace (May 2001); FAR 52.227-14 Rights In Data - General (MAY 2014), FAR 52.228-5 Insurance - Working On a Government Installation (JAN 1997); and FAR 52.232-33 Payment by Electronic Funds Transfer - System for Award Management (JULY 2013). The Contractor shall comply with the following clauses, which are incorporated in this contract in full text, to implement provisions of law or Executive orders applicable to acquisitions of commercial items. 52.217-5 Evaluation of Options (JULY 1990) Except when it is determined in accordance with FAR 17.206(b) not to be in the Government's best interests, the Government will evaluate offers for award purposes by adding the total price for all options to the total price for the basic requirement. Evaluation of options will not obligate the Government to exercise the option(s).(End of clause)52.217-8 Option to Extend Services, (NOV 1999) The Government may require continued performance of any services within the limits and at the rates specified in the contract. These rates may be adjusted only as a result of revisions to prevailing labor rates provided by the Secretary of Labor. The option provision may be exercised more than once, but the total extension of performance hereunder shall not exceed 6 months. The Contracting Officer may exercise the option by written notice to the Contractor within 60 days from the expiration of the contract. (End of clause) 52.217-9 Option to Extend the Term of the Contract, (MAR 2000) (a) The Government may extend the term of this contract by written notice to the Contractor within the current period of performance; provided that the Government gives the Contractor a preliminary written notice of its intent to extend at least 30 days before the contract expires. The preliminary notice does not commit the Government to an extension. (b) If the Government exercises this option, the extended contract shall be considered to include this option clause. (c) The total duration of this contract, including the exercise of any options under this clause, shall not exceed 60 months. (End of clause) NOTICE OF SMALL BUSINESS SET-ASIDE General. Offerors are solicited only from small business concerns. The procurement is to be awarded only to one or more such concerns, organizations, or individuals. This action is based on a determination by the Contracting Officer, alone or in conjunction with a representative of the Small Business Administration, that it is in the interest of maintaining or mobilizing the Nation's full productive capacity, or in the interest of war or national defense programs, or in the interest of assuring that a fair proportion of Government procurement is placed with small business concerns. Bids or proposals received from others will be considered non-responsive. Definitions. The term "small business concern" means a concern, including its affiliates, which is independently owned and operated, is not dominant in the field of operation in which it is bidding on Government contracts, and can further qualify under the size standards in this solicitation. In addition to meeting these criteria, a small business concern submitting an offer in his own name shall furnish, in the performing the contract, only end items manufactured or produced by small business concerns in the United States or its outlying areas, provided that this additional requirement does not apply in connection with construction or service contracts. COMMITMENT OF PUBLIC FUNDS The Contracting Officer is the only individual who can legally commit the Government to the expenditure of public funds in connection with the proposed procurement. Any other commitment, either explicit or implied, is invalid. TRAVEL Travel Costs - Commercial Costs for lodging, meals, and incidental expenses incurred by Contractor personnel shall be considered to be reasonable and allowable to the extent they do not exceed on a daily basis the per diem rates set forth in the Federal Travel Regulations, General Services Administration (GSA). Therefore, if travel costs are applicable and proposed by offerors, please be advised that they shall be calculated using the per diem rate schedule as established by GSA. Reimbursement of travel costs under any contract awarded from this RFP shall be in accordance with FAR 31.205-46. Travel Policy One copy of the offeror's (and any proposed subcontractor's) written travel policy shall be included in the business proposal. If an offeror (or any proposed subcontractor) does not have a written travel policy, the offeror shall so state.ON-SITE CONTRACTOR ACCESS TO GOVERNMENT PROPERTYThe Contractor shall be held responsible for Government Property, regardless of dollar value, when: 1. The contract requires contractor personnel to be located on a Government site or installation;2. The property utilized by contractor personnel is incidental to the place of performance; and,3. The property used by the contractor remains accountable to the Government Responsibility includes physical presence, proper use and handling, normal maintenance, and reporting loss, damage or destruction. Responsibility for government property shared by two or more contractors or located in space shared by two or more contractors shall be determined and documented by the contractors involved. In cases where the parties cannot reach agreement on shared responsibility, the matter will be referred to the NIH Property Officer for resolution. POST AWARD EVALUATION OF CONTRACTOR PERFORMANCE a. Contractor Performance Evaluations Interim and Final evaluations of Contractor performance will be prepared on this contract in accordance with FAR Subpart 42.15. The Final performance evaluation will be prepared at the time of completion of work. In addition to the Final evaluation, Interim evaluation(s) will be prepared annually as follows on July 1st. Interim and Final evaluations will be provided to the Contractor as soon as practicable after completion of the evaluation. The Contractor will be permitted thirty days to review the document and to submit additional information or a rebutting statement. If agreement cannot be reached between the parties, the matter will be referred to an individual one level above the Contracting Officer, whose decision will be final. Copies of the evaluations, Contractor responses, and review comments, if any, will be retained as part of the contract file, and may be used to support future award decisions. b. Electronic Access to Contractor Performance Evaluations Contractors may access evaluations through a secure Web site for review and comment at the following address: http://www.cpars.gov CONTRACTING OFFICER REPRESENTATIVE The following Contracting Officer's Representative (COR) will represent the Government for the purpose of this contract:To be specified prior to award The COR is responsible for: (1) monitoring the Contractor's technical progress, including the surveillance and assessment of performance and recommending to the Contracting Officer changes in requirements; (2) interpreting the statement of work and any other technical performance requirements; (3) performing technical evaluation as required; (4) performing technical inspections and acceptances required by this contract; and (5) assisting in the resolution of technical problems encountered during performance. The Contracting Officer is the only person with authority to act as agent of the Government under this contract. Only the Contracting Officer has authority to: (1) direct or negotiate any changes in the statement of work; (2) modify or extend the period of performance; (3) change the delivery schedule; (4) authorize reimbursement to the Contractor for any costs incurred during the performance of this contract; (5) otherwise change any terms and conditions of this contract; or (6) sign written licensing agreements. Any signed agreement shall be incorporated by reference in Section K of the contract The Government may unilaterally change its COR designation. COMMUNICATIONS PRIOR TO CONTRACT AWARD Offerors shall direct all communications to the attention of the Contract Specialist cited herein. Communications with officials outside of the contracting office may compromise the competitiveness of this acquisition and result in cancellation of the requirement. CLOSING STATEMENT Interested Offerors may submit quotations electronically to this notice no later than 8:00 AM. (EST) May 16, 2016. Questions regarding this solicitation must be received in writing by this office no later than May 1, 2016. Offerors must submit a completed FAR 52.212-3. The quotation shall include fully-burdened hourly wage rates for the key personnel assigned to this requirement. The Government intends to make a single award based upon best value to the Government, technical and price factors considered. The anticipated award date for this requirement shall be on or before June 15, 2016. Facsimile submissions are not authorized and collect calls will not be accepted. Submit offers to Andriani Buck at the address listed herein. Please reference the solicitation number HHS-NIH-NIDA-SSSA-RFP-16-47 on your offer. Requests for information concerning this requirement are to be addressed to Andriani Buck via e-mail to andriani.buck@nih.gov prior to the date stated above.

Distributed Antenna System and Maintenance

Other Defense Agencies, Uniformed Services University of the Health Sciences | Published June 9, 2016  -  Deadline July 9, 2016
cpvs

The Uniformed Services University of the Health Sciences (USU) is the Nation's federal health sciences university and is committed to excellence in military medicine and public health during peace and war. We provide the Nation with health professionals dedicated to career service in the Department of Defense and the United States Public Health Service and with scientists who serve the common good. We serve the uniformed services and the Nation as an outstanding academic health sciences center with a worldwide perspective for education, research, service, and consultation; we are unique in relating these activities to military medicine, disaster medicine, and military medical readiness. USU is located in Bethesda, MD on the grounds of the Naval Support Activity Bethesda.USU intends to negotiate on a sole source basis with Inflexion Management Sciences LLC, located in Silver Spring, MD for Engineering Professional services to install services and maintain the installed distributed antenna system (DAS) in USUHS building D location and for Engineering Professional services to service and maintain the installed distributed antenna system (DAS) in the 10 USUHS buildings and AFRRI buildings.These equipment and services will be procured in accordance with the procedures of FAR Part 12-Commercial Items and FAR Part 13-Simplified Acquisition Procedures.Sole source determination is made in accordance with:FAR Part 13.106-1 Soliciting Competition(b) Soliciting from a single source(1) For purchases not exceeding the simplified acquisition threshold, contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available.The mission of USU is to provide the highest quality education programs in the health sciences to those selected individuals who demonstrate dedication to a health profession career in the Uniformed Services. To do so, we need to ensure full operation of the existing communications platforms. The 5Bars cellular distributed antenna system is one of these communications platforms. The DAS is a complex system consisting of interfaces to four commercial cellular carrier systems (AT&T, Sprint, T-Mobile, and Verizon Wireless), repeater equipment, fiber cabling, coax cabling, and antennas distributed throughout our buildings.Over the last 2 years, we experienced complaints from D building staff of not being able to receive cellular coverage for all cellular carriers. The personnel in our D building were unable to use cellular service for their mobile devices to communicate over voice, text or data, losing an entire communications platform. Without mobile communications, personnel are tied to desks where they can log in and access data, and use desk phones. In addition, over a period of time, we experienced outages where our AFRRI buildings lost all cellular coverage for all cellular carriers. We contacted the company that installed the system to request support to resolve the issue. While the service was down, there was intermittent or no cellular coverage throughout the AFRRI buildings. The personnel in the AFRRI buildings were unable to use cellular service for the mobile devices to communicate over voice, text or data, losing an entire communications platform. Without mobile communications, personnel are tied to desks where they can log in and access data, and use desk phones. Inflexion Management Sciences LLC is the company that installed the original system and our infrastructure. They understand the complete system architecture/infrastructure and what we need to extend services to D building. This will allow them to install, troubleshoot, maintain, isolate any problems, resolve any issues, in order to have a smooth installation without any interruptions andprovide maintenance to all of USUHS. A company unfamiliar with the existing architecture will require many hours to learn the architecture and will be unable to respond in such a timely manner. We will potentially lose valuable weeks and perhaps months while they familiarize themselves with our infrastructure.Inflexion also has a full understanding of the interfaces with the cellular carriers and the agreements that USUHS has in place with the cellular carriers for the services that each cellular carrier is to provide to USUHS.Taking the above reasons into consideration Inflexion Management Sciences LLC is the only known source that can provided the requested equipment and services. This is not a request for quotes and a solicitation package will not be issued. Sources interested in responding to this requirement must be able to provide compelling evidence that they can provide the abovementioned requirement as specified. A determination by the government not to compete this proposed contractual action based upon responses received is solely within the discretion of the government. Responses must be received via email (stephen.enokida@usuhs.edu) by 10:00 a.m. EST on July 9, 2016.

NLM Discovery and Delivery Platform

Department of Health and Human Services, National Institutes of Health | Published December 15, 2014  -  Deadline December 30, 2014
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In accordance with FAR Part 12 and FAR Part 13, Simplified Acquisition procedures, the National Institutes of Health (NIH) intends to procure the acquisition of of web-based discovery and delivery software as well as the technical, management, and support services for implementing and maintaining the platform. The North American Industry Classification System (NAICS) Code is 541511. The anticipated base year period of performance is JANUARY 9, 2015 - JANUARY 8, 2015 with four 12-month option years. NLM is issuing this Statement of Work (SOW) for purchasing web-based discovery and delivery software. The Library seeks to acquire the software hosted by a vendor with the technical expertise, resources, and experience to provide NLM with an industry-leading search platform. The scope of this procurement is the acquisition of web-based discovery and delivery software as well as the technical, management, and support services for implementing and maintaining the platform. The vendor shall host discovery and delivery software that provides a single, modern, and intuitive search platform for NLM's physical, electronic, and digital resources. It must interoperate with the library's ILS to enable users to remain in the search platform for research and traditional OPAC functionality such as requests for physical materials in the NLM collections. The software architecture should be open and extensively configurable, customizable, and expandable for incorporation of additional collection resources and for further NLM development in response to future needs. The vendor must establish security policies, procedures, and practices that meet the relevant security requirements set forth by the U.S. Federal Government. All of the mandatory requirements have to be fulfilled by the vendor's solution. For those desirable requirements that the vendor's software cannot currently meet, the vendor may opt to propose an alternative approach or method. Contract Type: This is a fixed price contract. The Statement of Work and Request for Quotations are attached. All interested parties shall submit electronic responses to Ryan Singletary at ryan.singletary@nih.gov. Responses must be received no later than 12:00 PM EST on DECEMBER 9, 2014. Questions and inquiries regarding this notice may be sent to ryan.singletary@nih.gov until Friday, DECEMBER 19, 2014. The following clauses apply: FAR Clause 52.212-1 Instructions to Offerors Commercial; As stated in FAR Clause 52.212-2 (a), FAR Clause 52.212-3, Offeror Representations and Certifications Commercial Items; FAR Clause 52.212-4, Contract Terms and Conditions Required To Implement Statues or Executive Orders Commercial Items, Contract Terms and Conditions Commercial Items; and FAR Clause 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items Deviation for Simplified Acquisitions.

NHLBI Centralized Omics REsource (CORE)

Department of Health and Human Services, National Institutes of Health | Published March 29, 2016
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  Pre-Solicitation Notice NHLBI Centralized Omics REsource (CORE)  The National Heart, Lung, and Blood Institute (NHLBI) is seeking sequencing centers for the five-year Centralized Omics REsource (CORE) program.  The purpose of this announcement is to provide a Presolicitation Notice for the release of Solicitation NHLBI-CSB-HV-2016-36-JS.  THIS IS A SYNOPSIS.  THIS IS NOT A SOLICITATION. NHLBI's Trans-Omics for Precision Medicine (TOPMed) program seeks to discover factors that influence disease risk, identify subtypes of disease, and develop more targeted and personalized treatments. In addition to providing a comprehensive view of the genetic architecture, an unprecedented rich and multilayered data resource will be available to the scientific community stimulating innovative approaches to examine novel questions and generate cutting-edge methodologies to address heart, lung, blood, and sleep (HLBS) disorders. The program couples Whole Genome Sequencing (WGS) with additional phenotype data using Trans-Omic approaches by generating and incorporating Omics technologies such as DNA methylation, RNA expression patterns, and metabolic profiling with other extant phenotype and clinical outcome data from studies focused on HLBS disorders. The resulting data will be made available to approved investigators. NHLBI's CORE contract program provides whole genome sequencing and other Omics measures including DNA methylation, RNA expression patterns and metabolic profiling for use with other phenotype and clinical outcome data from studies focused on HLBS disorders. Thus the program in conjunction with NHLBI's TOPMed Program, seeks to discover factors that influence disease risk, identify subtypes of disease, and develop more targeted and personalized treatments. In addition to providing a comprehensive view of genetic, molecular, and cellular architecture, the unprecedented rich data resource generated by CORE will be available to the scientific community stimulating innovative approaches to examine novel questions to address HLBS disorders.  The objective of this Indefinite Delivery, Indefinite Quantity (IDIQ) contract is to generate Omics data for studies selected by NHLBI for participation in TOPMed. Omics technologies include Large Scale WGS, DNA Methylation, RNA Sequencing, Metabolic Profiling, and Novel Omics Technologies. This requirement is a partial small business set-aside. All interested offerors, both small and large, may submit a proposal. The associated NAICS code for this requirement is 541380, with a small business size standard of $15M NHLBI plans to establish a multiple award IDIQ as a result of the anticipated solicitation and will issue task orders to the established IDIQ holders. The majority of task orders are anticipated to be Cost Reimbursement.  The IDIQ will be for a five (5) year period of performance and a four and a half (4.5) year ordering period.  Source selection will be based on a best value trade-off evaluation. This is not a Request for Proposal (RFP) and the Government is not committed to award a contract pursuant to this announcement.  This advertisement does not commit the Government to award a contract.  The RFP will be available on the FedBizOpps Web page at http://www.fedbizopps.gov. Prospective offerors are responsible for downloading the RFP and all attachments. The offeror is responsible for monitoring the FedBizOpps Web page for the release of the solicitation and any amendments. The RFP will be available from the FedBizOpps on or about April 15, 2016.

Purchase of Analysis Engines for integration and concurrent processing of whole-slides digital image analyses

Department of Health and Human Services, National Institutes of Health | Published August 21, 2015  -  Deadline September 3, 2015
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General Information Short Title: Purchase of Analysis Engines® for integration and concurrent processing of whole-slides digital image analyses Document Type: Presolicitation Notice Solicitation Number: N02RC54102-43 Proposed Posted Date: August 21, 2015 Proposed Response Date: September 3, 2015 Classification Code: 7030 AOP Software NAICS Code: 541511 Computer Programming Services Business Size Standard: $27.5 Million Contracting Office Address Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E156, Bethesda, MD 20892, UNITED STATES Description The National Cancer Institute (NCI), Cancer Center Research (CCR), Laboratory of Cancer Biology and Genetics (LCBG), Molecular Pathology Unit, plans to procure on a sole source basis the brand name Analysis Engines® from Indica Labs, Inc., 2469 Corrales Road, Bldg. A-3, Corrales, NM 87048. This acquisition will be processed under FAR Part 12 - Acquisition for Commercial Items and will be made pursuant to the authority in FAR 13.106-1(b)(1) and 13.501-(a)(1) using simplified acquisition procedures for commercial acquisitions. The North American Industry Classification System code is 541511 and the business size standard is $27 Million. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. It has been determined there are no opportunities to acquire green products or services for this procurement. Delivery Date: 30 days from date of award. The Molecular Pathology Unit (MPU) conducts research and development in computer-assisted diagnosis. Digital imaging and computational analysis enables more reproducible quantitative and accurate cancer tissue specimen analysis. Project technology benefits cancer research and improves disease diagnosis through generation of data aimed at revealing disease mechanisms. The Molecular Pathology Unit (MPU) will upgrade its current computer assisted image analyses system by adding a server powered by tandem software Analysis Engines® compatible with existing configuration. This will allow for efficient use and increased application of Indica Lab's HALO® whole-slide image analysis resources and will also aid the ability to share data and algorithms created. The Analysis Engines® must integrate HALO® analysis software and storage components with the 10 current software licenses supplied MPU from Indica Labs previously. This acquisition will allow for the upgrading to image processing for computational biological analysis of NCI cancer specimens, while maintaining compatibilities with existing database and operating architecture. Indica Labs, Inc. will provide proprietary Analysis Engines® to seamlessly integrate with existing instrument system architecture and software to improve existing performance and extend technical capabilities. The following salient characteristics apply to the Analysis Engines® software: • Stream and analyze svs file images stored on eSlide database, previously captured with Aperio AT2 digital slide scanner. • Integrate seamlessly with HALO® viewer and modules. • Run batch analyses using image analysis algorithms created in HALO® from any of MPU's 10 computers with Indica Labs software licenses. • Run 8 whole-slide image analyses concurrently, relying on existing software compatibilities. • Store image analysis data in HALO® format and recall the data in that format within the HALO® viewer module. • Allow HALO® data sharing between all 10 HALO® software licensed computers. • Allow Classifier algorithms created by an individual user, as well as the data output, to be shared among the group. Indica Labs directly handles all HALO® configurations, including the Analysis Engines®. Indica Labs is able to provide the Analysis Engines® which are compatible and fully capable of being licensed with MPU's existing system architecture from Indica Labs. Indica Labs indicated that although they do have marketers of HALO® analysis software tools, those other entities have no knowledge of the HALO® analysis configurations or the Analysis Engine set-up and proprietary software. Indica Labs is able to provide the requisite Analysis Engines® with the capability to integrate parallel processing with the HALO analysis software, due to the proprietary nature of the software and its' integration. This notice is not a request for competitive quotation. However, if any interested party, especially small businesses, believes it can meet the above requirement, it may submit a capability statement, proposal, or quotation, which shall be considered by the agency. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Responses must be received in the contracting office by 11:00am EST, on September 3, 2015. All responses and questions must be in writing and faxed 240-276-5401 or emailed to Terry Galloway, Contracting Officer via electronic mail at gallowaytl@mail.nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. In order to receive an award, contractors must be registered and have valid certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA) through sam.gov. Reference: N02RC54102-43 on all correspondence.

Articulate Software

Other Defense Agencies, Uniformed Services University of the Health Sciences | Published July 6, 2016  -  Deadline July 18, 2016
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The Uniformed Services University of the Health Sciences (USU) is the Nation's federal health sciences university and is committed to excellence in military medicine and public health during peace and war. We provide the Nation with health professionals dedicated to career service in the Department of Defense and the United States Public Health Service and with scientists who serve the common good. We serve the uniformed services and the Nation as an outstanding academic health sciences center with a worldwide perspective for education, research, service, and consultation; we are unique in relating these activities to military medicine, disaster medicine, and military medical readiness. USU is located in Bethesda, MD on the grounds of the Naval Support Activity Bethesda.USU intends to negotiate on a sole source basis with Articulate Global Inc., located in New York, New York for software development of academic distribute learning content. This equipment will be procured in accordance with the procedures of FAR Part 12-Commercial Items and FAR Part 13-Simplified Acquisition Procedures.Sole source determination is made in accordance with:FAR Part 13.106-1 Soliciting Competition(b) Soliciting from a single source(1) For purchases not exceeding the simplified acquisition threshold, contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available.The mission of USU is to provide the highest quality education programs in the health sciences to those selected individuals who demonstrate dedication to a health profession career in the Uniformed Services. As such, it is essential USU provide the necessary training and equipment required for our students to become successful doctors and nurses and to be able to provide the best care possible for our soldiers and to support our research efforts. The USU is part of an International effort to implement the open source Learning RecordStores to assemble information on student activity to provide meaningful analytics to faculty and students, predict success and early signs of academic jeopardy and monitor student interaction with content. USU under contract with Unicon is helping to fund the development of the Open LRS and Open Dashboard architecture which stores/displays student data for analysis. This system is coming on line summer 2016. USU faculty are developing content that is hosted in Sakai but does not use the Sakai database to record student interactions (e.g. what a student worked on, how a knowledge check was answered, movement through content). To enable this to be tracked in OpenLRS USU also tasked Unicon to develop the appropriate data exchange methods between Articulate (which is used now in the curriculum) and the OpenLRS. Articulate StoryLine is the only content development product on the market today from which we can gather data for recording in OpenLRS and display in OpenDashboard. Articulate Global Inc. is the sole provider of access to their proprietary software Articulate Online. Articulate Global Inc. is the only know source that can provided the requested equipment. This is not a request for quotes and a solicitation package will not be issued. Sources interested in responding to this requirement must be able to provide compelling evidence that they can provide the abovementioned requirement as specified. A determination by the government not to compete this proposed contractual action based upon responses received is solely within the discretion of the government. Responses must be received via email (stephen.enokida@usuhs.edu) by 11:00 a.m. EST on July 18, 2016.

Upgrade and Implementation to Cisco Unified Communications System - Version 10.5

Other Defense Agencies, Uniformed Services University of the Health Sciences | Published March 8, 2016  -  Deadline March 21, 2016
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SOLE SOURCE NOTICE The Uniformed Services University of the Health Sciences (USU) is the Nation's federal health sciences university and is committed to excellence in military medicine and public health during peace and war. We provide the Nation with health professionals dedicated to career service in the Department of Defense and the United States Public Health Service and with scientists who serve the common good. We serve the uniformed services and the Nation as an outstanding academic health sciences center with a worldwide perspective for education, research, service, and consultation; we are unique in relating these activities to military medicine, disaster medicine, and military medical readiness. USU is located in Bethesda, MD on the grounds of the Naval Support Activity Bethesda.The Uniformed Services University of the Health Sciences (USU), located in Bethesda, MD, intends to negotiate on a sole source basis with World Wide Technologies (WWT), located in Lanham, MD, for an upgrade to Cisco Unified Communications System - Version 10.5 which includes design, implementation, testing, documentation, and training. This equipment will be procured in accordance with the procedures of FAR Part 12 Acquisition of Commercial Items and FAR Part 13 Simplified Acquisition Procedures. Sole source determination is made in accordance with: FAR 13.106-1 Soliciting competition. (b) Soliciting from a single source.(1) For purchases not exceeding the simplified acquisition threshold.(i) Contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available. The USU is the only Federal health sciences university and we are committed to excellence in military medicine and public health during peace and war. We provide the Nation with health professionals dedicated to career service in the Department of Defense (DoD) and the United States Public Health Service (PHS) and with scientists who serve the common good. We serve the uniformed services and the Nation as an outstanding academic health sciences center with a worldwide perspective for education, research, service, and consultation; we are unique in relating these activities to military medicine, disaster medicine, and military medical readiness. USU is located in Bethesda, MD on the grounds of the Naval Support Activity Bethesda. Cisco upgrade is a delicate process that must be done by a Cisco Gold partner which WWT is. The WWT team installed the VOIP system for USUHS and are the only ones who know the system and configuration in detail; understanding how to fix the current issues, given their understanding of the complete system architecture and infrastructure. World Wide Technology, Inc. is the only know source that can provided the requested upgrade and implementation. This is not a request for quotes and a solicitation package will not be issued. Sources interested in responding to this requirement must be able to provide compelling evidence that they can provide the abovementioned requirement as specified. A determination by the government not to compete this proposed contractual action based upon responses received is solely within the discretion of the government. Responses must be submitted via email to jason.motala@usushs.edu by 10:00 PM EST on March 21st, 2016.

Leasing of 34 Parking Spaces at 7700 Wisconsin Ave

Department of Health and Human Services, Program Support Center | Published January 26, 2016  -  Deadline January 29, 2016
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Pursuant to the authority of FAR 13.106-1(b)(1)(i), the Contracting Officer may solicit from one source if the Contracting Officer determines that the circumstances of the contract action deem only one source is reasonably available. The Department of Health and Human Services (DHHS), Program Support Center (PSC), Acquisition Management Services (AMS), on behalf of the Administrative Operations Portfolio (PSC/AOP) intends to sole source to: SP Plus Corporation1225 Eye Street, NWSuite C100Washington, DC 20005 In accordance with FAR 5.207(c), PSC/AOP's requirement is described as follows: (1) National Stock Number (NSN): N/A (2) Specification: Leasing of 34 Parking Spaces at 7700 Wisconsin Ave., Bethesda, MD (3) Manufacturer: N/A (4) Functional Description: Leasing of 34 Parking Spaces at 7700 Wisconsin Ave., Bethesda, MD (5) Predominant material of manufacture: N/A (6) Quantity: N/A (7) Unit of issue: N/A (8) Destination information: DHHS/PSC/DAM/AOP/OD7700 Wisconsin Ave., Bethesda, MD (9) Delivery Schedule: (10) Duration of the contract period: February 1, 2016 through January 31, 2017 (11) Sustainable acquisition requirements: N/A (12) Description of Procedure: This is a presolicitation notice of intent to sole source. This is not a solicitation for competitive proposal. No solicitation document is available. The anticipated award date is no later than January 30, 2016. (13) Architect-Engineer Project: N/A (14) Trade Agreement Clauses: N/A (15) Sole Source Justification: The Department of Health and Human Services (DHHS), Program Support Center (PSC), Acquisition Management Services (AMS), on behalf of the Administrative Operations Portfolio (PSC/AOP) intends to sole source to: SP Plus Corporation1225 Eye Street, NWSuite C100Washington, DC 20005 PSC/AOP has a need to lease 34 Parking Spaces located in Bethesda, MD. PSC/AOP intends to award a firm fixed price purchase order on a sole source basis to SP Plus Corporation. (16) This is not a solicitation for competitive proposal. No solicitation document is available. All responsible sources that have determined that they can provide the same services may submit product information and a capabilities statement. The email subject line must reference PSC169053 - 34 Parking Spaces. All responses are due by Friday, January 29, 2016 at 1:00PM Eastern Time and can be sent to Epe Pacantara at Epe.Pacantara@psc.hhs.gov. A determination by the Government not to compete this proposed contract base upon responses to this notice is solely within the discretion of the government.  

Leasing of 65 Parking Spaces at 7700 Wisconsin Ave

Department of Health and Human Services, Program Support Center | Published March 17, 2016  -  Deadline March 22, 2016
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Pursuant to the authority of FAR 13.106-1(b)(1)(i), the Contracting Officer may solicit from one source if the Contracting Officer determines that the circumstances of the contract action deem only one source is reasonably available. The Department of Health and Human Services (DHHS), Program Support Center (PSC), Acquisition Management Services (AMS), on behalf of the Financial Management & Procurement Portfolio (PSC/FMP) intends to sole source to: SP Plus Corporation1225 Eye Street, NWSuite C100Washington, DC 20005 In accordance with FAR 5.207(c), PSC/FMP's requirement is described as follows: (1) National Stock Number (NSN): N/A (2) Specification: Leasing of 65 Parking Spaces at 7700 Wisconsin Ave., Bethesda, MD (3) Manufacturer: N/A (4) Functional Description: Leasing of 65 Parking Spaces at 7700 Wisconsin Ave., Bethesda, MD (5) Predominant material of manufacture: N/A (6) Quantity: N/A (7) Unit of issue: N/A (8) Destination information: DHHS/PSC/DAM/FMP/OD7700 Wisconsin Ave., Bethesda, MD (9) Delivery Schedule: (10) Duration of the contract period: February 1, 2016 through January 31, 2017 (11) Sustainable acquisition requirements: N/A (12) Description of Procedure: This is a presolicitation notice of intent to sole source. This is not a solicitation for competitive proposal. No solicitation document is available. The anticipated award date is no later than March 26, 2016. (13) Architect-Engineer Project: N/A (14) Trade Agreement Clauses: N/A (15) Sole Source Justification: The Department of Health and Human Services (DHHS), Program Support Center (PSC), Acquisition Management Services (AMS), on behalf of the Financial Management & Procurement Portfolio (PSC/FMP) intends to sole source to: SP Plus Corporation1225 Eye Street, NWSuite C 100Washington, DC 20005 PSC/FMP has a need to lease 65 Parking Spaces located in Bethesda, MD. PSC/FMP intends to award a firm fixed price purchase order on a sole source basis to SP Plus Corporation. (16) This is not a solicitation for competitive proposal. No solicitation document is available. All responsible sources that have determined that they can provide the same services may submit product information and a capabilities statement. The email subject line must reference PSC170006- 65 Parking Spaces. All responses are due by Tuesday, March 22, 2016 at 1:00PM Eastern Time and can be sent to Keisha Palmer at Keisha.Palmer@psc.hhs.gov. A determination by the Government not to compete this proposed contract base upon responses to this notice is solely within the discretion of the government.

3D Bio-Printer for NCATS Tissue Engineering

Department of Health and Human Services, National Institutes of Health | Published July 25, 2016  -  Deadline August 10, 2016
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3D Bio-Printer for NCATS Tissue Engineering Competitive Combined Synopsis/Solicitation  HHS-NIH-NIDA-SSSA-CSS-16-458 INTRODUCTIONThis is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. This acquisition is being conducted in accordance with the procedures of FAR Part 13--Simplified Acquisition Procedures, FAR Subpart 13.5--Test Program for Certain Commercial Items, and FAR Part 12--Acquisition of Commercial Items.The solicitation number is HHS-NIH-NIDA-SSSA-CSS-16-458 and the solicitation is issued as a request for quotation (RFQ). NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODEThe intended procurement is classified under NAICS code 334516 with a Size Standard of 1,000 Employees. SET-ASIDE STATUSThis acquisition is unrestricted. Businesses of any size classification may respond.ACQUISITION AUTHORITY This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, FAR Subpart 13.5--Test Program for Certain Commercial Items, and FAR Part 12-Acquisition of Commercial Items, and IS expected to exceed the simplified acquisition threshold.  The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-89, dated July 14, 2016. The resultant contract will include all applicable provisions and clauses in effect through this date. DESCRIPTION OF REQUIREMENT BackgroundThe National Center for Advancing Translational Sciences (NCATS) applies the tools of small molecule screening and discovery to the development of chemical probe research tools for use in the study of protein and cell functions, and biological processes relevant to physiology and disease. NCATS uses bio-printing tissue engineering techniques to optimize biochemical, cellular and model organism-based assays submitted by the biomedical research community.PurposeThe purpose of this acquisition is to purchase one (1) 3D bio-printer to increase capability and throughput for bio-printing live tissues. Project RequirementsThe NCATS requires (1) 3D Bio-printer to bio-print tissues with the following capabilities: A. The system shall be able to extrude cell embedded matrix in a 3 dimensional design. B. The system shall include at least 4 print heads to accommodate tissue construction of multiple cell types in a specific geometry for a single print. C. The system shall be able to print with a wide range of needle diameter from ~60um-800um to allow creation of large or smaller details in the tissue architecture.D. The system shall be able to calibrate the needle positions before each print using laser calibration or an equivalently precise method, to enable precision in print architecture.E. The system shall be equipped to either heat (up to ~80C) or cool (down to ~5C) all print heads, to accommodate printing matrices which must be kept at specific temperatures. F. The system shall be able to dispense using a range of syringe volumes. NCATS anticipates using the following volumes in its efforts: 3mL - 10mL.G. The system is expected to accommodate print materials including hydrogel and liquid media. H. Liquid dispense capability shall be able to extrude droplets of media for precise placement of low cell density droplets. (~.005mm) I. The system shall be capable of extruding small volumeJ. The system shall enable contact dispensing for hydrogels as well as contactless (jetting) dispensing processes for liquids to enable high dispense frequency, and accuracy.K. The system shall include a thermobase platform heater (up to ~80C) and cooler (down to ~5C)L. The system shall include UV curing capability for photo-polymerization.M. The system shall be able to secure the position of multiwell plates with SBS footprint, and shall have a reliable method to secure odd shaped receptacles to keep the position snug. N. The system shall include 3D drawing software to create tissue architecture, as well as converter software to generate the script protocol for the printer. O. The system shall include a Biosafety Cabinet class 2 to provide sterility and operator safety to contain it which is strong enough to withhold the weight of the printer and fitted to hold the size. TrainingThe Contractor shall provide end-user training to teach NCATS employees to operate the system hardware and software. Training shall be provided by an Original Equipment Manufacturer technician. WarrantyThe Contractor shall provide a one (1) year warranty on all equipment, parts and repairs except where damage is deliberate, instrument is dropped or misuse beyond instructions provided. All products shall be warranted to be free from material defects in workmanship or material under normal use and service for the warranty period. Delivery Requirements/Period of PerformanceThe anticipated contract period of performance is sixteen (16) weeks from date of award. The contractor shall deliver and install the required equipment within sixteen (16) weeks after receipt of order. Delivery must be FOB Destination and must include inside installation. The equipment shall be delivered and installed between the hours of 8:00am and 5:00pm, Rockville, MD local prevailing time, Monday through Friday. The contractor shall provide a company certified service technician to perform installation. Place of PerformanceThe required equipment shall be delivered and installed inside at NIH/NCATS; Building B; 9800 Medical Center Drive; Rockville, MD 20850 Contract TypeThe Government intends to issue a firm fixed price commercial items contract for this requirement. Question and Answer PeriodInterested contractors may submit questions relating to this requirement. Questions shall be submitted to the contract specialist, Lauren Phelps, via email at lauren.phelps@nih.gov by or before 07/29/2016 at 12:00 PM Noon EST. Late questions shall not be accepted. Questions will be anonymized and answered and the answers will be provided as soon as possible after the question deadline via solicitation amendment. Should no questions be received, no amendment shall be posted. RESPONSE FORMAT Responses to this solicitation must include clear and convincing evidence of the offeror's capability of fulfilling the requirement as it relates to the technical evaluation criteria. The offeror must submit 1) a technical response and 2) a separate price quotation. The technical response should address each of the evaluation criteria four separately. The contractor price quotation must cover all of the requirements listed in this solicitation and include the itemized associated pricing. Contractors must provide their Company Name, Dun & Bradstreet Number (DUNS), Taxpayer Identification Number (TIN), Business Size, Physical Address, and Point of Contact Information in their responses. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov."IMPORTANT NOTE TO OFFERORS: PROPOSALS MUST INCLUDE BOTH A TECHNICAL RESPONSE AND A SEPARATE PRICE QUOTE. CONTRACTORS NOT SUBMITTING BOTH A TECHINICAL RESPONSE ADDRESSING THE EVALUATION CRITERIA AND A SEPARATE PRICE QUOTE SHALL NOT BE CONSIDERED.EVALUATION CRITERIA FAR clause 52.212-2, Evaluation - Commercial Items applies to this acquisition and the specific evaluation criteria to be included in paragraph (a) of that provision are as follows: The Government will award a purchase order resulting from this solicitation on the basis of best value in consideration of both technical factors and price. Technical factors are as follows, in order of importance:1. Equipment Capability and Warranty (60 Points):The contractor shall detail in a technical proposal how its proposed equipment meets each of the project requirements. This shall include detailed specifications of the offered equipment and its capabilities as well as warranty information. The technical proposal shall be evaluated for the ways in which the proposed equipment meets the functional equipment specification requirements. The Government shall particularly evaluate for the system's capability and accuracy in printing with small volumes, the broadness of range of included needle diameters and syringe volumes, and for the methods of dispensing hydrogel and liquid media efficiently and accurately. The warranty shall be evaluated for the ways it meets or exceeds the requirements detailed in this statement of work. Exceeding requirements shall be considered favorably 2. Training (20 Points):The contractor shall detail in a technical proposal the end user training is shall provide including subjects covered, technicians/instructors, and training duration. The Government shall evaluate the training approach for its comprehensiveness and appropriateness to teach at least four NCATS employees to appropriately use the equipment independently. 3. Delivery and Installation (10 Points):The contractor shall detail in a technical proposal how it shall meet the delivery and installation requirements. The Government shall evaluate for ability to meet or exceed the requirements detailed in this statement of need (delivery and installation within 16 weeks). Proposals must include a delivery lead-time and detailed explanation of who shall perform installation. 4. Past Performance (10 Points):The Contractor shall provide a list of two (2) contracts or purchase orders completed during the past five (5) years, similar in size and scope to the equipment provision, delivery, and installation requirements outlined in this Statement of Work. Experience shall include the following information for each contract or purchase order listed: a. Name of Contracting Organizationb. Total Contract Valuec. Description of Requirement d. Contract Period of Performance Past Performance shall be evaluated for relevance to the current requirement. Proposals shall be evaluated using an adjectival ranking system based on evaluation points as follows:Excellent (90-100)Very Good (80-89)Fair (70-79)Poor (60-69)Unacceptable (0-59)Only adjectival ratings shall be used in final summary technical evaluation documentation.APPLICABLE CLAUSES AND PROVISIONSThe following FAR clauses and provisions shall apply to this solicitation:1. All Offerors MUST be actively registered in the System for Award Management (SAM) www.sam.gov. 2. The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items (April 2014), applies to this acquisition. 3. FAR clause 52.212-2, Evaluation - Commercial Items (October 2014) applies to this acquisition. 4. A completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items (March 2015), is required with any offer submitted. This requirement may be met by completion of the provision in the System for Award Management. 5. FAR clauses 52.212-4, Contract Terms and Conditions - Commercial Items (May 2015) and 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items (June 2016) apply to this acquisition. 6. FAR Clause 52.237-2 -- Protection of Government Buildings, Equipment, and Vegetation applies to this acquisition. 7. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. In addition, the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." CONTRACTOR PERFORMANCE EVALUATIONFinal Evaluation of Contractor performance will be prepared for the resulting contract in accordance with FAR Subpart 42.15. The final performance evaluation will be prepared at the time of completion of work. Final evaluation will be provided to the Contractor as soon as practicable after completion of the evaluation. The Contractor will be permitted thirty days to review the document and to submit additional information or a rebutting statement. If agreement cannot be reached between the parties, the matter will be referred to an individual one level above the Contracting Officer, whose decision will be final. Copies of the evaluation, Contractor responses, and review comments, if any, will be retained as part of the contract file, and may be used to support future award decisions. Contractors may access evaluations through a secure Web site for review and comment at the following address: http://www.cpars.gov CONTRACTING OFFICER'S REPRESENTATIVEA Contracting Officer's Representative (COR) shall be assigned to the awarded contract. The COR is responsible for: (1) monitoring the Contractor's technical progress, including the surveillance and assessment of performance and recommending to the Contracting Officer changes in requirements; (2) interpreting the statement of work and any other technical performance requirements; (3) performing technical evaluation as required; (4) performing technical inspections and acceptances required by this contract; and (5) assisting in the resolution of technical problems encountered during performance.The Contracting Officer is the only person with authority to act as agent of the Government under this contract. Only the Contracting Officer has authority to: (1) direct or negotiate any changes in the statement of work; (2) modify or extend the period of performance; (3) change the delivery schedule; (4) authorize reimbursement to the Contractor for any costs incurred during the performance of this contract; (5) otherwise change any terms and conditions of this contract; or (6) sign written licensing agreements. Any signed agreement shall be incorporated by reference in Section K of the contractThe Government may unilaterally change the COR designation for this contract. CLOSING INFORMATIONResponses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. All responses must be received by the closing date of this announcement and must reference solicitation number HHS-NIH-NIDA-SSSA-CSS-16-458. Responses shall be submitted electronically via email to Lauren Phelps, Contract Specialist, at lauren.phelps@nih.gov.  

Optimization of FT-EPR imaging methods

Department of Health and Human Services, National Institutes of Health | Published June 1, 2016  -  Deadline June 10, 2016
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Contracting Office Address Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Bethesda, MD 20892, UNITED STATES. Description The National Cancer Institute (NCI), Biophysical Spectroscopy Section of the Radiation Biology Branch (RBB), CCR, plans to procure on a sole source basis consulting services and assistance to obtain analytical tools on general architecture of algorithms from GenEpria Consulting Inc, 10015 Old Columbia Rd, Suite B-215 Columbia, MD 21046. This acquisition will be processed under FAR Part 12 - Acquisition for Commercial Items and will be made pursuant to the authority in FAR 13.106-1 (b)(2) and 13.501-(a)(1) using simplified acquisition procedures for commercial acquisitions. The North American Industry Classification System code is 541690 and the business size standard is $14.0 Million. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. The period of performance is twelve (12) months from date of award. It has been determined there are no opportunities to acquire green products or services for this procurement. The NCI and the RBB is conducting two major projects requiring both intensive statistical and programming applications. The first project involves studies on the effect of the antioxidant nitroxide, Tempol, on the gut microflora of mice continuously feed tempol containing mouse chow over many months. The second is a continuation project on radiation metabolomics to determine the metabolites predictive of cancer types. The RBB is preparing to set up another long term mouse urine metabolite study to see if short term metabolic profiles are predictive of cancer induction post IR (ionizing radiation) exposure.Contractor Requirements are: 1. Integrated EPR Oximetry suite for EPRI at 400 MHz frequency. The data acquisition and image reconstruction software for the EPRI system operating at 400 MHz providing an efficient work flow. The acquisition and display software is to be upgraded to the operating system of the computer running 400 MHz scanner. 2. Implementation of novel pulse programs for EPRI using waveform generator. Develop software to program the waveform generator for multi sequence pulse programs such as Hadamard, Frank and other pulse sequences that would reduce the specific absorption rate (SAR). Develop algorithm to pipeline the multi sequence acquisition data through the image reconstruction modules for EPRI at 400 MHz. 3. Real time visualization of FT-EPR imaging at 400 MHz. Develop algorithms for image visualization during acquisition. Devise faster image processing algorithms to allow the display of the image real time during acquisition. 4. Algorithms for Co-registration of images scanned by 400 MHz EPRI with other modalities. The purpose of this algorithm is to relate the quantities determined by MRI to the quantities determined by EPRI at 400 MHz such as pO2 in order to examine their relationships. 5. Oximetry by T2* mapping using single SPI-EPRI acquisition at 400 MHz. This requirement is to implement a new algorithm developed by RBB and University of Wisconsin to increase the speed of oxygen mapping by about 3 times in single point imaging (SPI) mode at 400 MHz. Oximetry by T2* conventionally requires three SPI-EPRI scans at three different maximum gradients. The new algorithm uses gridding and k-space extrapolation of data from single SPI-EPRI acquisition offering a three-fold scan speed and better image quality. 6. Statistical analysis of gut microbiota 16S sequencing data of mice on Tempol feed. Analyze the effect of the antioxidant nitroxide, Tempol, on the gut microflora of mice continuously feed tempol containing mouse chow over many months. Identify the specific signatures relevant to the tempol effect GenEpria has successfully completed previous assignments with RBB on similar approaches in this field. GenEpria previously developed custom made algorithms for co-registration among MRI, EPRI and other modalities for the use with oximetry from EPRI and anatomic and functional images obtained from MRI at 7T. Bringing another vendor at this point will force the Government to invest additional time and money to allow the new vendor to familiarized with existing algorithms. GenEpria is the only vendor known to perform the proposed Statement of Work by RBB. This notice is not a request for competitive quotation. However, if any interested party, especially small business believes it can meet the above requirement, it may submit a proposal or quote for the Government to consider. The response and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Responses must be received in the contracting office by 4 PM EST, on June 10, 2016. All responses and questions must be in writing and faxed to 240-276-5399 or emailed to Reyes Rodriguez, Contracting Officer via electronic mail at reyes.rodriguez@nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. In order to receive an award, contractors must be registered and have valid certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA) through sam.gov. Reference: N02RC62594-57 on all correspondence.

Web Programming and Database Maintenance on the Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS) Study

Department of Health and Human Services, National Institutes of Health | Published January 27, 2016  -  Deadline February 5, 2016
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PRE-SOLICITATION NOTICE OF INTENT INTRODUCTION:THIS IS A PRE-SOLICITATION NOTICE OF A PROPOSED CONTRACT TO ACTION. The National Institute on Drug Abuse (NIDA), Station Support Contracts and Simplified Acquisitions Branch (SS/SA) on behalf of the National Institute of Aging intends to negotiate and award a contract for the "Web Programming and Database Maintenance on the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) Study". EXTENT OF COMPETITION:This acquisition is full and open with a total small business set-aside restriction. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE:The intended procurement is classified under NAICS code 541511 with a Size Standard of $27.5 Million. REGULATORY AUTHORITY:The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2005-85-1 dated January 4, 2016. This acquisition is conducted under the procedures as prescribed in FAR subpart 12-Acquisition of Commercial Items at an amount not exceeding the simplified acquisition threshold ($150,000). DESCRIPTION OF REQUIREMENT:Background:The National Institute on Aging Intramural Research Program has embarked on a longitudinal study of the effects of race and socioeconomic status on healthy aging in a representative sample of community-dwelling residents from the Baltimore metropolitan region. This study, Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS), requires expertise in database management, web design, the connection between web interfaces and data as well as the application of life-time development techniques. Purpose and Objectives:The Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study requires a Perl-CGI programmer, which is a high-level, general-purpose, interpreted and dynamic programming language for programming Common Gateway Interface (CGI) web applications, to write dynamic web-based applications for collecting, summarizing and reporting medical, physiological and psychological data. The services provided will be writing novel applications as well as upgrading and management of existing applications facilitating electronic collection, review, and distribution of clinical data for the HANDLS study. Additional services include design, testing, and implementation of applications to enhance functionality of existing applications described in the scope of work section below; expertise with existing technologies should combine with knowledge of emerging state-of-the-art practices, languages, databases, and management procedures. Applications include a dynamic web user interface with logic for consistency checking connected with existing databases and tables as required. Web-based applications include but are not limited to a structured medical history with options for updating existing information, physical performance battery, participant contact and status information, physical examination, participant scheduling, participant and participant's primary care physician letters and results reports (packets), field tracking and tracing notes and contacts, phone contacts tracking, home visit versions of these applications, scheduling for examinations on the mobile research vehicles, and scheduling and eligibility for HANDLS scan, nutritional interview, experience with diabetes study, home visits, and other ancillary studies as they arise. Maintenance, support, and extension of all deliverables are expected. Period of Performance:Base Year: March 1, 2016 to February 28, 2017 Optional Renewal Years:Option Year 1: March 1, 2017 to February 28, 2018 Option Year 2: March 1, 2018 to February 28, 2019 Option Year 3: March 1, 2019 to February 28, 2020Option Year 4: March 1, 2020 to February 28, 2021 Project Description:An individual web user-interface and database programmer is required and shall be responsible for providing database management services, web-design, establishing the connection between web interfaces and data, as well as the application of life-time development techniques without resorting to formal business practice models. Specific techniques required are Perl/CGI and other web interface languages as required to supply specific study requirements as they arise. Consistency with existing approaches is paramount for ease and simplicity of management and maintenance. All changes in approach require approval of the Contracting Officer's Representative (COR).1. Web Application:At present, the web application is written in HTML, Perl/CGI, Perl/CGI-templates, Python, and Ruby on Rails, with some existing PHP code and PDFlib that is under conversion to Perl/CGI as time permits; database servers running Linux and deploying MySQL are currently used. Additional facilities required by these applications include ImageMagick, and Perl with template toolkit, Moose, CGI application toolkit, and Git server deployment, management, and use. Web application programmer shall have expertise in installing, managing, and maintaining Apache web server and MySQL server on production server and in a development environment. HANDLS plans to study the advisability of migrating to Maria or PostgreSQL; the current webserver is Apache on Linux. In addition, the web user interface database programmer shall be responsible for modifying existing web applications. Expertise is required to complete the development of web-based data collection tools to support the clinical research conducted by the HANDLS study. The web programs provide the facility to collect the clinical data in the mobile research vehicles and synchronize data with servers located in the Biomedical Research Center (BRC). In addition, study management modules for scheduling participants, tracing and tracking participants, recording notes about participant contacts, preparing results packets after participants are examined, and sending various mailings to participants are required at the Biomedical Research Center. 2. Database Management:The integrated web­ based system requires ongoing maintenance and enhancements, as well as tools for monitoring performance, particularly disconnections. Moreover, these applications must account for security and confidentiality of the information and data collected, clinical informatics and database design that can be supported with open-source tools, and web applications that meet current design standards and accessibility requirements, including Section 508 for accessibility by individuals with disabilities. The website also requires continued architecture of a system to replace the current authentication systems on the HANDLS servers to meet NIH standard. Existing web user interface and database follow general LAMP principles using the Linux operating systems, Apache webserver, MySQL database, and Perl/CGI as the dynamic web programming language. Modifications or adjustments to these principles require evidence of particular strengths and advantages to different technology plus estimates of costs and benefits. Any changes in LAMP principles shall require the approval of the COR. Specifically, the database programmer shall provide database management, web design, the connection between web interfaces and data, and application life-time development techniques and shall provide, but is not limited to, the following services below: a. Re-usable application design such that programs written for the present wave of data collection can be modified easily for data collection in subsequent waves. Contractor will support existing web applications and add functionality as required by study requirements, security considerations, or by changes and upgrades to the Linux operating system. Contractor must have a complete view of how all the parts of web site work together, including database synchronization and the function of the server at the field site. b. The design of the program must accommodate several goals, including comprehensive data collection, ease of navigation, and the capacity for direct transfer to other tools for statistical analyses. A variety of statistical programming tools are used to analyze these data (e.g., SAS, Stata, SPSS, R). However, there are no specific data formats required by these tools so long as all data are stored in well-designed SQL tables with data types that are interpretable by these programs. c. Development of web-based data collection tools to support the clinical research conducted by the HANDLS study. The web-tool provides the ability to collect the clinical data in the mobile research vehicles (MRV) and subsequently to upload the data to servers located in the Biomedical Research Center (BRC). The web application has multiple facets all of which work together. The data format for uploading, when necessary, depends on the device or instrument that produces the data. The format is determined by the device manufacturer. Often the format is CSV, but not always. As equipment is upgraded or revised, data requirements may change necessitated revisions to the upload procedures. The MRVs have a separate database and webserver so they can function independently and completely when there's a lapse in internet services. Therefore, special consideration is made in programming the website to insure that it works independently at both sites. In addition, the databases maintain a synchronization feature to insure (a) a backup of information is maintained throughout the day and (b) there's no confusion introduced between the field site (MRVs) and headquarters. Thus data entered at either site is replicated to the other site. This process requires careful monitoring and careful consideration during programming so as not to disrupt either site. Devices used on the MRVs are laptops and iPads to access the MRV website. d. The integrated web-based system requires ongoing maintenance and enhancements, as well as tools for monitoring performance, particularly disconnections. Intimate familiarity with clinical data is required to perform this task, as is knowledge of the interconnections among various procedures and tracking databases. e. These applications must account for security and confidentiality of the information and data collected clinical informatics and database design that can be supported with open­ source tools, and web applications that meet current design standards and accessibility requirements, including Section 508 for accessibility by individuals with disabilities. HANDLS data and webserver are built on Linux, Apache, MySQL and PHP (LAMP) principles with the Linux operating system using Apache webserver and MySQL database with Perl/CGI as the primary language for dynamic web pages. NIH deploys other open source facilities by drawing from the Comprehensive Perl Archive Network (CPAN); by deploying Python and Ruby on Rails where those languages provide uniquely advantageous features; by deploying various tools such as jQuery to standardize the AJAX environment. NIH's underlying policy is to avoid proprietary tools and languages in favor of tools and languages for which there a broad community of public users. f. The website requires continued architecture of a system to replace the current authentication systems on the HANDLS servers to meet NIH standards. Other Important Considerations:Level of Effort:A Perl-CGI Web Programmer is required for a total of 500 hours and must have a Bachelor's degree or equivalent in engineering, science, or any liberal arts.Deliverables:1. Description of Tasks and Associated Deliverables: Timely submission of deliverables is essential to successful completing this requirement. Tasks performed under this contract and their schedules are determined by the COR based on study requirements. 2. Reporting Requirements: The contractor shall provide in-progress demonstrations of work performed, beta-versions for testing, and all programming code and program libraries required to operationalize requirements specified by COR. The contractor shall enumerate the program files and processes on which work was performed, strategies for changing the code, implementing it, and training staff in its use. Weekly meetings are required in person to discuss coordinating work on the web site; to display progress on work; to insure consistency in approaches, particularly for the user interface; to insure identical versions of open-source software are used; and to work through policies and procedures for maintaining the web service and databases. Occasional demonstrations of work in progress are required as interim reports to insure that work is proceeding in the correct direction.Key Personnel:The following positions are considered "Key Personnel" in support of this contract initiative: o Perl-CGI web user interface designer programmer and database programmer 1. Minimum Bachelor's degree or equivalent in engineering, science, or any liberal arts.2. Minimum ten years experience in programming and at least five years experience webprogramming and managing data from clinical field studies using open-source languages in conjunction with Perl/CGI, Perl/Templates, MySQL database management and synchronization. Experience with clinical data are crucial because the HANDLS clinical management system is a real-time data entry and medical record database. Changes to one part of the system may have far­reaching consequences in other parts of the system and on the accuracy of the data.   CLOSING STATEMENT The solicitation will be issued on or about February 8, 2016, and bids or proposals will be tentatively due about 10 days after the solicitation release date. Potential offerors may request a copy of the solicitation from Samantha Kelly, Contract Specialist, electronically at Samantha.Kelly2@nih.gov. Please reference the solicitation number HHS-NIH-NIDA-SSSA-2016-118 on your electronic and fax request.

National Library of Medicine High Speed Internet Connectivity

Department of Health and Human Services, National Institutes of Health | Published August 5, 2016  -  Deadline August 23, 2016
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This is a combined synopsis/solicitation for a commercial service prepared in accordance with the format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a separate written solicitation will not be issued. This solicitation number is NIHLM2016864 and is issued as a Request for Proposal (RFP). The solicitation /contract will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2005-83. The North American Industrial Classification (NAICS) code 517110 with a size standard 1,500 employees. This acquisition is being conducted using Simplified Acquisition Procedures in accordance with FAR Part Subpart 13.5. The purpose of this contract is to provide high speed Internet connectivity to the National Library of Medicine's network which is located in Bethesda, Maryland. This will provide commodity Internet access to the public as well as the research and medical communities around the world. This connectivity needs to be provided via a Global Tier 1 Internet Service Provider (ISP). It must also include protected circuit connections from the ISP Point of Presence (POP) to the National Library of Medicine (NLM). This connectivity must provide 3 Gbps bandwidth. The provider must have the capability to upgrade the connections up to 10 Gbps bandwidth. Please see the attached Statement of Work dated May 03, 2016 for the complete scope of work. QUESTIONS: If you have any questions regarding this requirement, please submit your inquiries to April Merriwether, Contracting Officer, at merriwetheran@mail.nih.gov no later than August 11, 2016 at 11:00AM Eastern Standard Time. Questions with the Government's responses will be posted to FedBizOpps. Please be advised that the Government reserves the right to transmit those questions and answers of a common interest to all prospective Offerors. SUBMISSION REQUIREMENTS AND PROPOSAL DUE DATE:In order to receive an award, contractor must be registered and have a valid certification in the System For Award Management (SAM) http://www.sam.gov. Interested vendors capable of providing the Government with the services specified in this combined synopsis/solicitation shall submit electronic responses to merriwetheran@mail.nih.gov. Please reference solicitation number NIHLM2016864 on all correspondence to this notice. Proposals must be submitted electronically no later than August 23, 2016 at 11:00 AM EST. The proposal submitted shall be prepared in two volumes and clearly identified as: Volume 1: Technical Proposal and Volume 2: Business Proposal. Proposals shall be in sufficient detail to permit proper evaluation, negotiation, and/or acceptance thereof. The technical proposal must not contain reference to price; however, resource information (such as data concerning labor hours and categories, materials, subcontracts, etc.) must be contained in the technical proposal so that the offeror's understanding of the Statement of Work may be evaluated. The price proposal shall be submitted as a Fixed Price proposal with pricing for each element of the Statement of Work. In addition, our SOW states we are looking for a starting b/w speed of 3 Gbps with equipment capabilities in place to increase that b/w up to 10 Gbps. As a result, please include a pricing structure that will not only price the initial startup of 3Gbps, but also include the rate increases per increase in Gbps up to 10. Page Limit: 25 pages, excluding appendices. Formatting: Page size 8.5 by 11 inches with 1 inch margins. Paragraphs single spaced. Minimum font size/style 10 point Times New Roman font for Text, 9 point font in the Arial family for Tables, and 8 point font in the Arial family for Graphics. Tables and graphics may be landscape; all other text must be portrait. If the offeror uses a different format (font size, margin, etc.), the government reserves the right to adjust the proposal to fit the parameters of the format as stated in the RFP, and if this results in the proposal exceeding the page limitations in any one area, the government will not consider those excess pages. Period of Performance: The period of performance shall be for a base period of one year, with 4 one-year option periods. Base Period: 9/16/2016 - 9/15/2017; Option Pd. 1: 9/16/2017 - 9/15/2018; Option Pd. 2: 9/16/2018 - 9/15/2019; Option Pd. 3: 9/16/2019 - 9/15/2020; Option Pd. 4: 9/16/2020 - 9/15/2021 EVALUATION FACTORS FOR AWARD 1. GENERALSelection of an offeror for award will be based on the evaluation of proposals against three factors. The factors in order of importance are: technical, price, and past performance. Although technical factors are of paramount consideration in the award of the task order, price, and past performance are also important to the overall award decision. All evaluation factors other than cost price, when combined, are significantly more important than price. The Government intends to make an award to that offeror whose proposal provides the best overall value to the Government. The evaluation will be based on the demonstrated capabilities of the prospective contractors in relation to the needs of the project as set forth in the RFP. The merits of each proposal will be evaluated carefully. Each proposal must document the feasibility of successful implementation of the requirements of the RFP. Offerors must submit information sufficient to evaluate their proposals on the detailed factors listed below. 2. MANDATORY QUALIFICATION CRITIERIAThe offeror shall include all information which documents and/or supports the mandatory qualification criteria in one clearly marked section of its proposal. In addition, provide an index within the technical proposal which directs reviewers to the specific areas of the proposal that address each mandatory criterion. The mandatory qualification criteria establishes conditions that must be met at the time of receipt of Technical Proposals by the Contracting Officer in order for your proposal to be considered any further for award. The contractor must be considered a Global Tier 1 ISP. The National Library of Medicine defines a Global Tier 1 ISP as one that has the following attributes: • provides connections to the Internet via settlement-free interconnections. This means that there are not overt charges for the amount, direction, or type of traffic sent between networks;• has access to the entire Internet routing table through their peering relationships; • are interconnected at Internet Exchange (IX) points; • are not dependent on other ISPs to manage private peering;• peer on more than one continent; and• own or lease transoceanic fiber optic transport. 3. TECHNICAL EVALUATION FACTORSThe evaluation factors are used by the technical evaluation committee when reviewing the technical proposals. The factors below are listed in the order of importance with weights assigned for evaluation purposes.The criteria for evaluating the proposals are listed below: a. Network Architecture 30__pts NLM will evaluate the Offeror's network in terms of speed, latency, capacity, number and types of connections to other networks, traffic congestion points, and number of hops to other networks and key access points. In order to provide for adequate capacity and speed to meet future demands, the Offeror shall demonstrate a commitment to continuous review and enhancing the network architecture. The Offeror will describe its current and future plans for the implementation of IPv6. NLM will evaluate and determine if it meets the needs of our service requirements. It is anticipated that network technology will advance and improve significantly during the period of performance of the task order. NLM wishes to take advantage of any new capabilities, which will result either in reduced overall costs or result in new capabilities, which can satisfy NLM's requirements for services. The Offeror shall explain how it can and will incorporate new technologies into its network architecture, and how NLM can take advantage of these new capabilities. b. Network Reliability and Availability 30___ptsThe Government relies heavily on the Internet to provide network service and access to research and biomedical information for an international community. Disruption of this capability would impede the accomplishment of the mission of the Government. Therefore, the proposal will be evaluated in terms of factors, which affect the availability of the network services. The contractor shall provide service level agreements (SLA) that include the following:• Average monthly packet delivery• Average monthly latency in the contiguous U.S. and globally• Time to Repair (TTR) from trouble ticket creation to restoral The reliability of hardware and software components within a network are primary factors affecting network reliability. All components shall be of the highest quality and well maintained. The Offeror shall describe the historical availability and reliability of the network. Relevant statistics such as average error rates and packet loss as well as network up time can be used to show reliability. In the event of an outage somewhere in the provider's network, the ability to continue to provide connection and services via alternate routing paths within the provider's network and over connections to the Government is critical and shall be provided with explanation. The Offeror shall explain how it proposes to provide for reliable paths between the Government and the provider's POP (Point of Preference). c. Network Security 20___ptsThe Government has a requirement to protect its information resources from vulnerabilities, which are introduced by being connected to the Internet. The Offeror shall describe any programs, that it may have, which reduce the risk of various threats from malicious activity over the network. This description shall include, but is not limited to, what precautions the Offeror will take to detect and prevent "sniffing" of information over its network and Government connections, prevention of unauthorized access to the Offeror's NOC (Network Operations Center) and network nodes, detection of various types of network attacks, etc. Assistance with security matters, which would be available to the Government, shall be described. The method of providing DDoS (Distributed Denial-of-Service) attack mitigation will be evaluated. This service shall be able to detect DDoS attacks against NLM IT resources, and enable the mitigation of such attacks to enable NLM information services which are not under attack to continue to be accesses during such attacks. d. Corporate Related Experience 20__pts The Government will evaluate the past experience of the Offeror, with respect to providing similar ISP and DDoS services as specified in the Statement of Work (SOW). The Offeror shall describe past performance of comparable and related work, within the past three (3) years, similar in kind to that required under the task, including summaries of scopes of work, resource requirements, dollar values and points of contact for each body of work on past or current contracts (or under other arrangements). The Offeror shall provide contact information for these references.4. COST/PRICEOfferor(s) cost/price proposal will be evaluated for reasonableness. For a price to be reasonable, it must represent a price to the Government that a prudent person would pay when consideration is given to prices in the market. Normally, price reasonableness is established through adequate price competition, but may also be determined through cost and price analysis techniques as described in FAR 15.404.Although price is of less importance than the technical factors, taken as a whole, it is an important factor and should not be ignored. The degree of its importance will increase with the degree of equality of the proposals in relation to the other factors on which selection is to be based.The evaluation method used will allow the Government to make an award to an Offeror who may not be lowest in price, but who ostensibly offers the greatest value. The Government is more concerned with obtaining superior technical or management features than with making an award at the lowest overall price to the Government. However, the Government will not make an award at a significantly higher overall price to achieve slightly superior technical or management features. 5. EVALUATION OF OPTIONSIt is anticipated that any order awarded under this Request for Quotation will contain option provision(s) and period(s). In accordance with FAR Clause 52.217-5, Evaluation of Options (July 1990), the Government will evaluate offers for award purposes by adding the total price for all options to the total price for the basic requirement, except when it is determined in accordance with FAR 17.206(b) not to be in the Government's best interests. Evaluation of options will not obligate the Government to exercise the option(s). 6. PAST PERFORMANCEOfferor's past performance information will be evaluated subsequent to the technical evaluation. However, this evaluation will not be conducted on any offeror whose proposal is determined to be technically unacceptable.The evaluation will be based on information supplied by the offeror by way of past performance questionnaires. Questionnaires are to be completed on contracts or orders within the last 3 years that are similar in size and relevance. Please only provide questionnaires on three (3) past performance references. The questionnaires are to be sent directly to April Merriwether at merriwetheran@mail.nih.gov , no later than 12:00 noon EST on August 25, 2016. The Questionnaire Template is attached to the solicitation.The Government will assess the relative risks associated with each offeror. Performance risks are those associated with a vendor's likelihood of success in performing the acquisition requirements as indicated by that offeror's record of past performance. The assessment of performance risk is not intended to be a product of a mechanical or mathematical analysis of an offeror's performance on a list of contracts/orders, but rather the product of subjective judgment by the Government after it considers relevant information.When assessing performance risks, the Government will focus on the past performance of the offeror as it relates to all acquisition requirements, such as the vendor's record of performing according to specifications, including: standards of good workmanship; the offeror's record of controlling and forecasting costs; the offeror's adherence to contract schedules, including the administrative aspects of performance; the offeror's reputation for reasonable and cooperative behavior and commitment to customer satisfaction; and generally, the offeror's business-like concern for the interest of the customer.The Government will consider the currency and relevance of the information, source of the information, context of the data, and general trends in the offeror's performance. The lack of a relevant performance record may result in an unknown performance risk assessment, which will neither be used to the advantage nor disadvantage of the offeror. ATTACHMENTS: Attachment 1: Statement of Work, dated May 03, 2016Attachment 2: Past Performance Questionnaire FEDERAL ACQUISITION REQULATION (FAR) CLAUSESThe following provisions and clauses apply to this acquisition and are incorporated by reference. Full text may be found at https://www.acquisition.gov FAR 52.212-1 Instructions to Offerors-Commercial ItemsFAR 52.212-2 Evaluation-Commercial ItemsFAR 52.212-3 Offeror Representations and Certifications-Commercial ItemsFAR 52.212-4 Contract Terms and Conditions-Commercial ItemsFAR 52.212-5 Contract Terms and Conditions Required to Implement Statutes and Executive orders The offeror must include a completed copy of the following provisions with your proposal submission: FAR Clause 52.212-3, Offeror Representations and Certifications - Commercial Items and FAR Clause 52-212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items - Deviation for Simplified Acquisitions.    

National Institutes of Health (NIH) Office of Strategic Coordination(OSC) Common Fund Budget Management

Department of Health and Human Services, National Institutes of Health | Published August 14, 2015  -  Deadline September 14, 2015
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Statement of Work 1. Common Fund Budget Management US Department of Health and Human Services, National Institutes of Health (NIH), Office of the Director, Division of Program Coordination, Planning and Strategic Initiatives (DPCPSI), Office of Strategic Coordination (OSC) 2. Background OSC oversees the NIH Common Fund - an over 540 billion dollar annual appropriation that supports research in areas of emerging scientific opportunities, rising public health challenges, and knowledge gaps that deserve special emphasis that would benefit from strategic coordination and planning across the NIH Institutes and Centers (ICs). Common Fund programs are administered by Working Groups (WGs) composed of staff located throughout the 27 ICs. There are nearly 30 unique Working Groups - one for each Common Fund program. Careful budget management across these programs and across the ICs is critical to the success of the Common Fund. This requirement demands budget management capabilities equivalent to a GS-15 budget officer, and it requires the IT capabilities of a junior-level relational database programmer. This requirement is currently (period of performance: 9/30/10 - 9/30/15) being performed by Laurel Consulting Group (LCG) through subcontract to George Bramhall. 3. Objectives The NIH Office of the Director/Office of Strategic Coordination (OD/OSC) has a critical need for a contractor with the skills to manage the federal budget processes of formulation, presentation, and execution for the NIH Common Fund. OSC also has a critical need for a contractor with expertise in the administration of databases used for budget tracking, budget reporting, budget planning, and cost accounting for federal grant programs. Finally, the OSC seeks a contractor to develop, coordinate, monitor, and communicate the budget details to other budget officers and high level government officials. 4. Contract Type Fixed Price. 5. Services to be performed 5.1 Specific Tasks 5.1.1 Task 1 - Provide daily management of the NIH Common Fund budget. Formulation • Use OMB, HHS, and NIH guidance to develop the projected commitment base for different budget mechanisms for future fiscal years. • Develop mechanism tables and initiative tables that convey current and future funding. • Work closely with programmatic staff to predict and explain increases and decreases in program budgets. Presentation • Work with OSC and NIH staff to prepare the annual OMB Justification and Congressional Justification submissions for the Common Fund. Execution • Help coordinate responses to members of Congress on budgets questions regarding the Common Fund. • Coordinate the process of setting annual operating budgets for each of the approximately 30 Common Fund programs • Assist ICs in identifying RMS and IRP needs to run each Common Fund program. Coordinate the transfer of these funds to ICs via dozens of interagency agreements. • Advise OSC and IC staff on the availability of funds in each program and provide guidance on how to adjust program budgets to shift funds between projects. • Evaluate each request to pay new awards to ensure the awards are within budget. Identify opportunities to reclaim or shifts funds when needed. • Ensure the entire Common Fund budget has been spent by carefully tracking each obligation and working with IC staff to identify last minute options to spend funds. • Monitor expenditures; prepare and present budget reports. • Gather budget information from NIH Institutes and Centers. • Respond to budget data calls from various internal and external audiences. • Report from other NIH-wide grant, budget, and accounting systems. • Guide and train members of the OSC staff to assist in the tracking and management of Common Fund programs. 5.1.2 Task 2 - Administer online budget tracking tools. • Serve as Administrator of the SID database and other budget resources. Ensure all data is up-to-date and accurate. • On a daily basis, load new data from NIH systems in our budget databases. Check for and resolve any discrepancies that occur across these databases. • Enter data that is not managed by other NIH systems. • Ensure that awards and other data are coded correctly in the various NIH systems. • Resolve issues, especially end-of-year issues, associated with loading grants and awards into the database. • Make recommendations on how to improve or redesign the data architecture of the SID database in order to take advantage of new NIH resources or changes in OSCs tracking needs. • Assist with SID table modifications when new programs and activity codes are established. • Design and serve as programmer on other budget tracking tools and databases. Design table structures and relationships, queries, forms, and reports. • Create new reports as needed to assist OSC staff in tracking the budget of the Common Fund. • Instruct NIH staff on the use of these databases o Tracking number of submitted applications, accepted applications, number of applications in various stages. o Provide summary data, e.g. Totals and Summaries. 5.1.3 Task 3 - Coordinate and Communicate across IC leadership. • Coordinate budget communications with NIH Institutes and Centers. Interact regularly with IC budget officers, budget staff, and program leadership to explain the Common Fund budget processes and assist with resolving budgetary issues. • Provide regular reports to IC colleagues on the status of their program budgets, expenses, and funds available. • Participate in NIH Budget Officer Meetings to provide insight as to how IC systems and processes may intersect with Common Fund systems and processes. • Coordinate with the Office of the Director (OD) budget office on issues involving the entire OD budget (including the Common Fund). • Remain apprised of changes regarding NIH budget management by participating in trainings, conferences, and workshops. • Represent the perspective of the OD/OSC in budget working groups, committees, and meetings. 5.2 Period of Performance: The base period of performance is one year (12 months) from the date of contract award. There are four option periods of one year (12 months) each. Option periods are subject to availability of funds and may be unilaterally exercised by the Government. (Dates subject to changes based on award) Base Period: September 30, 2015 through September 29, 2016 Option Period 1: September 30, 2016 through September 29, 2017 Option Period 2: September 30, 2017 through September 29, 2018 Option Period 3: September 30, 2018 through September 29, 2019 Option Period 4: September 30, 2019 through September 29, 2020 5.3 Deliverables: Deliverable Required Measures of Success Indicators Standards-Criteria for Acceptable Quality Level Method of Surveillance The contractor shall provide daily updates to budget tracking databases Daily reports from systems reflect recent budget decisions. 100% compliance with government requirements and Technical Monitor Customer review and observation. Government inspections and acceptance The contractor shall provide monthly updates to IC colleagues on the status of project budgets. Delivered by the 30th of every month. 100% compliance with government requirements and Technical Monitor Customer review and observation. Government inspections and acceptance The contractor shall develop spreadsheets and databases to help manage and communicate budget and award data. Delivered as needed by request of OSC staff. 100% compliance with government requirements and Technical Monitor Customer review and observation. Government inspections and acceptance The contractor shall provide monthly status reports Delivered by the 15th of every month 100% compliance with government requirements and Technical Monitor Customer review and observation. Government inspections and acceptance 6. Program Management and Control Requirements 6.1 Contractor Requirements All work shall be performed in a professional manner and meet or exceed the government standards for performance. Contractor agrees to use its best efforts to undertake, carry out and complete for Government, in a satisfactory and competent manner, all work and services described in the scope of work. Contractor agrees to maintain liaison with the Government to ensure a well-integrated project effort. All information and materials developed pursuant to this contract are the property of the U.S. Government and fall within the purview of the Freedom of Information Act. The contractor is enjoined against unauthorized release of the facts, findings, and written materials from this contract without the expressed, written authorization of the Project Officer. The contractor and any employees, consultants, or subcontractors will be required to sign and abide by a non-disclosure agreement before commencing work. Pursuant to FAR 7.5, the Contractor shall not perform any inherently Governmental actions under this contract. No Contractor employee shall hold him or herself out to be a Government employee, agent, or representative. No Contractor employee shall state orally or in writing at any time that he or she is acting on behalf of the Government. In all communications with third parties in connection with this contract, Contractor employees shall identify themselves as Contractor employees and specify the name of the company for which they work. In all communications with other Government contractors in connection with this contract, the Contractor employee shall state that they have no authority to in any way change the contract and that if the other contractor believes this communication to be a direction to change their contract, they should notify the Contracting Officer for that contract and not carry out the direction until a clarification has been issued by the Contracting Officer. The Contractor shall insure that all of its employees working on this contract are informed of the substance of this article. Nothing in this article shall limit the Government's rights in any way under the other provisions of the contract, including those related to the Government's right to inspect and accept the services to be performed under this contract. The substance of this article shall be included in all subcontracts at any tier. 6.2 Privacy Act The contractor shall gather, process, maintain, analyze, and report data in accordance with Privacy Act guidelines and requirements and in accordance with the Office of Management and Budget (OMB) restrictions on information collection (see Paperwork Reduction Act at 44 U.S.C. 3501 et seq.). This Statement of Work requires the Contractor to access data covered under Privacy Act System of Records to include but not limited to: 09-25-0036, Extramural Awards and Chartered Advisory Committees (IMPAC 2), Contract Information (DCIS), and Cooperative Agreement Information, HHS/NIH). 09-25-0156, Records of Participants in Programs and Respondents in Surveys Used to Evaluate Programs of the National Institutes of Health The Contractor agrees to comply with the policies and practices defined in the System of Records listings for this data and any other Privacy Act system the contractor may have access to, and to the Privacy Act clauses for FAR 52.224.1 and 52.224-2, herein incorporated by reference. All data collected and datasets created shall be provided to the U.S. Government at the conclusion of this contract or upon request. The contractor shall retain no copies of data or other information collected or created under this contract. Furthermore, the contractor shall strive to minimize the resulting burden placed on respondents when collecting data from PIs or individuals. 6.3 Security 6.3.1 Homeland Security Presidential Directive (HSPD)-12 To perform the work specified herein, Contractor personnel are expected to have routine (1) physical access to an HHS-controlled facility; (2) physical access to an HHS-controlled information system; (3) access to sensitive HHS data or information, whether in an HHS-controlled information system or in hard copy; or (4) any combination of circumstances (1) through (3). To gain routine physical access to an HHS-controlled information system, and/or access to sensitive data or information, the Contractor and its employees shall comply with Homeland Security Presidential Directive (HSPD)-12, Policy for a Common Identification Standard for Federal Employees and Contractors; Office of Management and Budget Memorandum (M-05-24); and Federal Information Processing Standards Publication (FIPS PUB) Number 201; and with the personal identity verification and investigations procedures contained in the following documents: 1. HHS Information Security Program Policy ( http://www.hhs.gov/read/irmpolicy/121504.html ) 2. HHS Office of Security and Drug Testing, Personnel Security/Suitability Handbook, dated February 1, 2005 ( http://www.hhs.gov/ohr/manual/pssh.pdf ) 3. HHS HSPD-12 Policy Document, v. 2.0 ( http://www.whitehouse.gov/sites/default/files/omb/assets/omb/memoranda/fy2005/m05-24.pdf ) The Contractor shall include language similar to this "HHS Controlled Facilities and Information Systems Security" language in all subcontracts that require subcontractor personnel to have the same frequency and duration of (1) physical access to an HHS-controlled facility; (2) logical access to an HHS-controlled information system; (3) access to sensitive HHS data/information, whether in an HHS-controlled information system or in hard copy; or (4) any combination of circumstances (1) through (3). The Contractor shall direct inquiries, including requests for forms and assistance, to the Contracting Officer. 6.3.2 Federal Information Security Management Act The Federal Information Security Management Act of 2002 (P.L. 107-347) (FISMA) requires each agency to develop, document, and implement an agency-wide information security program to safeguard information and information systems that support the operations and assets of the agency, including those provided or managed by another agency, contractor (including subcontractor), or other source. The National Institute of Standards and Technology (NIST) has issued a number of publications that provide guidance in the establishment of minimum security controls for management, operational and technical safeguards needed to protect the confidentiality, integrity and availability of a Federal information system and its information. This Statement of Work requires the Contractor to perform one, or any combination, of the following: Develop, have the ability to access or host and/or maintain a Federal information system(s). Pursuant to Federal and HHS Information Security Program Policies the following requirements apply to this Work Order: Federal Information Security Management Act of 2002 (FISMA), Title III, E-Government Act of 2002, Pub. L. No. 107-347 (Dec. 17, 2002); http://csrc.nist.gov/drivers/documents/FISMA-final.pdf 6.4 Place of Performance and Government Furnished Equipment Office space, computer equipment (desktop and laptop), and specialized software will be provided by the OSC. The contractor may also regularly work offsite. The contractor will meet with OSC and IC staff regularly, so regular trips to the NIH Main Campus and off-campus offices are expected. 7. Post-Award Administration Past Performance Evaluations will be completed at least annually and at the end of the task. 8. Key Personnel Budget expert consultant that does budget management and IT work. 8.1 Skills and Knowledge Skilled, experienced personnel are essential for accomplishing the work to be performed. Key personnel shall be identified by name and title/job classification in offeror proposals. The contractor must possess administrative management skills and the ability to coordinate complex projects in a very short time frame. The contractor must possess expert knowledge of federal grants policies, federal budget procedures, and research grant mechanisms. The contractor must have experience in designing the data architecture of federal budget databases that focus on grants management. In particular, the contractor should have experience setting up tables, relationships, queries, forms, and reports for relational databases. The contractor must have experience responding to Congressional and OMB requests. The contractor must have experience communicating budget information to high-level government officials. 8.2 Substitutions The Contractor agrees that key personnel shall not be removed from the contract effort, replaced or added to the contract without a compelling reason. The Government will not approve substitutions for the sole convenience of the contractor. If any change to the key personnel position becomes necessary (substitutions or additions), the Contractor shall immediately notify the Contracting Officer in writing, accompanied by the resume of the proposed replacement personnel who shall be of at least substantially equal ability and qualifications as the individuals currently approved for that category. No substitution or replacement of the key personnel shall be approved within the first ninety (90) days after contract award. All requests for approval of changes hereunder must be in writing, via email, and provide a detailed explanation of circumstances necessitating the proposed change. Request for changes should be made whenever the need is identified. Beside the resume, the request must also provide: • A comparison of skills and qualifications to those set forth in the accepted resume proposed for substitution; • A signed employee procurement integrity agreement; • Number of hours the contractor will provide at his/her own expense to train the proposed replacement, and • Any other information requested by the Contracting Officer to reach a decision. Common Fund Budget Management - Evaluation Criteria Technical factors (shown below) are superior to price. If two vendors are technically equal, then price will be used as the deciding factor. A. Understanding of the Requirement - 30% • Including creativity and thoroughness shown in understanding the objectives of the SOW and specific tasks, and planned execution of the project. • Evidence of specific methods and techniques for completing each discrete task, to include such items as quality assurance and customer-service. • Ability to address anticipated potential problem areas, and creativity and feasibility of solutions to problems and future integration of new processes and technology enhancements. • Degree to which the offerors quote demonstrates an understanding of logistics, schedule, and any other miscellaneous issues in which the Government should be aware. B. Personnel Qualifications - 30% • For proposed personnel, describe the quality and depth of experience working on similar projects. Similar projects must convey similarity in topic, dollar value, workload, duration, and complexity. Evidence of the staff members' expertise, where it was applied, and length of experience must be provided. C. Technical Skills/Experience- 40% • The offeror must demonstrate and document that they have sufficient staff with the appropriate skill mix to provide the level of support required to meet the requirements of this contract. The proposed staff must have the training and experience to do the technical work required for the areas specified in the specific Tasks and subtasks. 1. Budget Personnel - 30% -- The contractor must possess expert knowledge of federal grants policies, federal budget procedures, and research grant mechanisms; and significant experience applying this knowledge in a federal budget management setting. 2. Database Personnel - 10% -- The contractor must have experience in designing the data architecture of federal budget databases that focus on grants management. In particular, the contractor should have experience setting up tables, relationships, queries, forms, and reports for relational databases. End.

Clinical and Immunological Investigation of Subtypes of Autism, Diagnosis and Treatment of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental Disorders, and other PDN neurophysiology data

Department of Health and Human Services, National Institutes of Health | Published March 24, 2016  -  Deadline April 7, 2016
cpvs

INTRODUCTIONThis is a pre-solicitation non-competitive (notice of intent) synopsis to award a contract without providing for full or open competition (including brand-name). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL. A SOLICITATION WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institute on Drug Abuse (NIDA), Consolidated Station Support and Simplified Acquisitions (CSS/SA) Branch intends to negotiate and award a purchase order to University of Vermont for clinical and immunological investigation of subtypes of autism, diagnosis and treatment of childhood-onset behavioral disorders, neuropsychiatric disorders and neurodevelopmental disorders, and other PDN neurophysiology data reimbursement without providing for full and open competition (including brand-name). NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODEThe intended procurement is classified under NAICS code 622110. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2005-87 dated March 7, 2016. This acquisition is for a commercial item or service and is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures. This acquisition is NOT expected to exceed the simplified acquisition threshold. STATUTORY AUTHORITY This acquisition is conducted under the authority of the authority of FAR Subpart 13.106-1. DESCRIPTION OF REQUIREMENT Background InformationThe Pediatrics and Developmental Neuroscience Branch (PDN) is in the process of analyzing data collected as part of a large phenomenological study of children with autism compared with children with other developmental disabilities and with typically developing children. As part of our medical and clinical evaluation, the children all had electroencephalograms and modified polysomnograms (without respiratory parameters). Our preliminary neurophysiologic data from our modified polysomnograms for the first 60 children with autism reveals that many of them have abnormal sleep architecture when compared to the other two groups. These differences in the organization of the sleeping bran likely reflect differences in underlying neural organization. Purpose and ObjectivesThe contractor shall analyze polysomnographic and EEG data collected from participants from NIMH's PDN branch in the following manner: a) Power spectral analysis awake and asleepb) Paired electrode coherencesc) The construction of network mapsd) The quantification of epileptiform activitye) Analysis of changes in connectivity pre and post sleep manipulation with donepezil.f) Analysis of recordings will occur in a blinded fashion with only the patient's age available which will afford the best possible interpretation of data. Contractor RequirementsThe contractor shall provide maps of the neural networks of the subjects involved in the above protocols. The contractor will perform hierarchical clustering on a configured data matrix to determine the intrinsic groupings of networks within the study population. To further investigate the ability of correlation networks to classify children with autism and to extract defining structural features from these networks, the contractor shall use support vector machines (SVM). The analyses will consist of between-group comparison of all electrophysiological measures (power [absolute, relative, and ratios], spectral coherence/Pearson correlations, phase lag, and amplitude asymmetry). Coherence values will be subjected to Fisher-transformation for statistical analysis. The contractor will not have access to government facilities or government websites. The contractor will not be restricted from saving or printing data from their own network; however, the contractor is not required to save data to their network resources to evaluate it. All data analysis will be submitted to NIMH. None of the results will be published unless approved by NIMH. Period of PerformanceThe period of performance shall be a 12 month period with two (2) 12 month option periods. A firm fixed price purchase order is contemplated. CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME) DETERMINATIONThe determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted. Specifically, only the University of Vermont (UVM) is capable of meeting the needs of this requirement due to the extensive clinical experience in EEG sigma analysis both in animals and humans. UVM has a laboratory for Dr. Gregory Holmes which is involved in animal models of autism and epilepsy and utilizes state-of-the-art electrophysiological methods to understand neural networks in the developing brain. Analyses performed will allow researchers at NIMH to accomplish the goals of several clinical research protocols. The intended source is: The University of Vermont Medical Center, Inc.111 Colchester Ave.Burlington, VT 05401 CLOSING STATEMENTTHIS SYNOPSIS IS NOT A REQUEST FOR COMPETITIVE PROPOSALS. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by the closing date and time of this announcement and must reference the solicitation number. Responses may be submitted electronically to Megan Ault, Contract Specialist, at megan.ault@nih.gov. US Mail and Fax responses will not be accepted.

Haskris Model OPC 10 or equivalent Chiller

Department of Health and Human Services, National Institutes of Health | Published September 17, 2015  -  Deadline September 23, 2015
cpvs

COMBINED SYNOPSIS / SOLICITATION This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The solicitation number is HHS-NIH-NIDA-(SSSA)-15-887 and the solicitation is issued as a request for quote (RFQ). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures and FAR Part 12-Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold. The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2005-84 effective September 3, 2015. This acquisition is unrestricted. The associated NAICS code 334516 and the small business size standard 500. STATEMENT OF OBJECTIVES The purpose of this requirement is acquisition of a Haskris Model OPC 10 or equivalent Chiller. Title: Haskris Model OPC 10 or equivalent Chiller The National Institute of Neurological Disorders and Stroke (NINDS) is a part of the National Institutes of Health (NIH), conducting research into the causes, treatment, and prevention of neurological disorders and stroke. The NINDS mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. The NIH Mouse Imaging Facility (MIF) is dedicated to providing state-of-the-art anatomical, functional and molecular medical imaging capabilities for animal models of human disease. Scope of Work The Contractor shall provide a Haskris Model OPC 10 or equivalent Chiller meeting the following requirements: 1. Due to space concerns the chiller dimensions must be no larger than 49x36x76 inches to allow the chiller to be situation on a concrete area that is 5.6 feet and still allow the necessary clearance for service to occur. 2. Weather resistant architecture tested for specification before delivery. a. The chiller should be individually rain tested in down pour conditions for a minimum of three hours with no negative effects. b. The chiller should be tested under a full load for a minimum in high ambient temperatures ranging from 100-120 degrees for a minimum of 24 hours. 3. Heat load to handle at least 25 kilo Watts. 4. Pump capacity of at least 16 Gallons per minute with a remote control panel designed to interlock with the chiller. The remote control to set and operate temperature and display fault status. 5. Chiller must display Process temperatures and fault status to be displayed. 6. Maintain a stock of replacement parts for next day shipment. 7. Customer tech support is free of charge. 8. Must be compatible with a Bruker cryo coil. Contract Type: A firm fixed price purchase order is anticipated. Period of Performance/Delivery Requirements: Delivery date must be flexible due to site renovations. Eight (8) weeks notice will be given before the necessary delivery date. Place of Performance: The required equipment shall be delivered and installed at the NIH Main Campus, Building 10, 9000 Rockville Pike, Building 10, Room B1D69, Bethesda, MD 20892, Bethesda, MD 20892 for delivery and set-up. FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. Offerors must include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items, with its offer. FAR clause 52.212.-2, Evaluation - Commercial Items, is applicable to this requirement. (a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate offers: The Government will award a delivery order resulting from this solicitation on the basis of best value, technical factors and price considered. Technical factors together shall be considered more important than price. The technical evaluation factors are as follows, in order of importance: 1. Factor 1: Technical Approach The Offeror shall detail in its technical proposal how it shall meet each of the project requirements. This shall include the specifications of the offered equipment, specifically if and how it is an equal-to-brand-name quotation. 2. Factor 2: Delivery The Offer shall detail in its technical proposal how it shall meet the delivery requirements. The Government shall particularly evaluate ability to meet delivery and installation schedule requirements. Quotations must include a delivery lead time. Technical evaluation factors and past performance, when combined, are significantly more important, when compared to price. (c) A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer's specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award. (End of Provision) FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All responses must be received by September 23, 2015, 8:00 am EST and must reference number HHS-NIH-NIDA-(SSSA)-15-887. Responses may be submitted electronically to andriani.buck@nih.gov or by U.S. mail to the National Institute of Drug Abuse (NIDA), Station Support / Simplified Acquisition Branch (SS/SA), 31 Center Drive, Building 31, Room 1B59, Bethesda, Maryland 20892-2080, Attention: Andriani Buck. Fax responses will not be accepted.